Selected Publications
Narayan, V.; Barber-Rotenberg, J.S.; Jung, I-Y.; Lacey, SF.; Rech, AJ.; Davis, MM.; Hwang, W-T.; Lal, P.; Carpenter, EL.; Maude, SL.; Plesa, G.; Vapiwala, N.; Chew, A.; Moniak, M.; Sebro, RA.; Farwell, MD.; Marshall, A.; Gilmore, J.; Lledo, L.; Dengel, K.; Church, SE.; Hether, TD.; Xu, J.; Gohil, M.; Buckingham, TH.; Yee, SS.; Gonzalez, VE.; Kulikovskaya, I.; Chen, F.; Tian, L.; Tien, K.; Gladney, W.; Nobles, CL.; Raymond, H.; Prostate Cancer Cellular Therapy Program Investigators, Hexner, EO.; Siegel, DL.; Bushman, FD.; June, CH.; Fraietta, JA.; Haas, NB.: PSMA-targeting TGFβ-insensitive Armored CAR T-cells in Metastatic Castration Resistant Prostate Cancer: a Phase 1 Trial Nat Med 28 (4): 724-734,2022.
Jonasch, E.; Donskov, F.; Iliopoulos, O.; Rathmell, WK.; Narayan, V.; Maughan, BL.; Oudard, S.; Else, T.; Maranchie, JK.; Welsh, SJ.; Thamake, S.; Park, EK.; Perini, RF.; Linehan, WM.; Srinivasan, R.: Belzutifan for Von Hippel-Lindau Disease–Associated Renal Cell Carcinoma New Engl J Medicine
385 (22): 2036-2046,2021.
Dorff, TB.;* Narayan, V.;* Forman, SJ.; Zang, PD.; Fraietta, JA.; June, CH.; Haas, NB.; Priceman, SJ.: Novel Redirected T Cell Immunotherapies for Advanced Prostate Cancer Clin Cancer Res 28 (4): 576-584,2021.
Pal, SK.; Tangen, C.; Thompson, IM.; Haas, NB.; George, DJ.; Heng, D.; Shuch, B.; Stein, M.; Tretiakova, M.; Humphrey, P.; Adeniran, A.; Narayan, V.; Bjarnason, G.; Vaishampayan, U.; Alva, A.; Zhang, T.; Cole, S.; Plets, M.; Wright, J.; Lara, P.: A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial Lancet 397 (10275): 695-703,2021.
Sharma, P.; Pachynski, RK.; Narayan, V.; Fléchon, A.; Gravis, G.; Galsky, M.; Mahammedi, H.; Patnaik, A.; Subudhi, SK.; Ciprotti, M.; Simsek, B.; Saci, A.; Hu, Y.; Han, GC.; Fizazi, K.: Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial Cancer Cell 38 (4): 489-499,2020.
Narayan, V.; Harrison, M.; Cheng, H.; Kenfield, S.; Aggarwal, R.; Kwon, D.; McKay, R.; Hauger, R.; Hart, N.; Conzen, S.; Borno, H.; Jim, H.; Dicker, A.; Dorff, T.; Moslehi, J.; Mucci, L.; Parsons, JK.; Saad, F.; Soule, H.; Morgans, A.; Ryan, CJ.: Improving Research for Prostate Cancer Survivorship: A Statement from the SuRECaP (Survivorship Research in Prostate Cancer) Working Group Urologic Oncology: Seminars and Original Investigations 38 (3): 83-93,2020.
Narayan, V.; Puligandla, M.; Haas, NB.; Subramanian, P.; DiPaola, RS.; Uzzo, R.: Patterns of Relapse and Implications for Post-Nephrectomy Surveillance for Patients with High-Risk Non-Clear Cell Renal Cell Carcinoma: Subgroup Analysis of the Phase 3 ECOG-ACRIN E2805 Trial J Urol 201 (1): 62-68,2019.
Narayan, V.; Keefe, S.; Haas, NB.; Wang, L.; Puzanov, I.; Putt, M.; Catino, A.; Fang, J.; Agarwal, N.; Hyman, D.; Smith, AM.; Finkelman, B.; Narayan, HK.; Ewer, S.; ElAmm, C.; Lenihan, D.; Ky, B.: Prospective Evaluation of Sunitinib-Induced Cardiotoxicity in Patients with Metastatic Renal Cell Carcinoma Clin Cancer Res 23 (14): 3601-3609,2017.
Schram, AM.; Colombo, N.; Arrowsmith, E.; Narayan, V.; Yonemori, K.; Scambia, G.; Zelnak, A.; Bauer, TM.; Jin, N.; Ulahannan, SV.; Colleoni, M.; Aftimos, P.; Donoghue, M.; Rosen, E.; Rudneva, V.; Telli, ML.; Domchek, SM.; Galsky, M.; Hoyle, M.; Chappey, C.; Stewart, R.; Blake-Haskins, JA.; Yap, TA.: Avelumab Plus Talazoparib in BRCA1/2- or ATM-Altered Advanced Solid Tumors (JAVELIN BRCA/ATM): Results From an Open-Label, Multicenter, Phase 2b, Tumor-Agnostic Trial JAMA Oncology 17 : e225218,2022.
Jung, IY.; Narayan, V.; McDonald, S.; Rech, AJ.; Bartoszek, R.; Hong, G.; Davis, MM.; Xu, J.; Boesteanu, AC.; Barber-Rotenberg, JS.; Plesa, G.; Lacey, SF.; Jadlowsky, JK.; Siegel, DL.; Hammill, DM.; Cho-Park, PF.; Berger, SL.; Haas, NB.; Fraietta, JA.: BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion Sci Transl Med 14 (670): doi: 10.1126/scitranslmed.abn7336.,2022.
Narayan, V.; Ross, AE.; Parikh, RB.; Nohria, A.; Morgans, AK.: How to Treat Prostate Cancer With Androgen Deprivation and Minimize Cardiovascular Risk: A Therapeutic Tightrope J Am Coll Cardiol CardioOnc 3 (5): 737-741,2021.
Narayan, V.: Comparing Cardiovascular Outcomes with Degarelix or Leuprolide as Prostate Cancer Therapy -- Applying Real-World Data to Clinical Trial Emulation JAMA Netw Open
4 (10): e2131429.,2021.
Sun, L.; Parikh, RB.; Hubbard, R.; Cashy, J.; Takvorian, SU.; Vaughn, DJ.; Robinson, KW.; Narayan, V.*; Ky, B*.: Assessment and Management of Cardiovascular Risk Factors Among US Veterans With Prostate Cancer JAMA Netw Open 4 (2): e210070,2021.
Ravi, P.; Mantia, C.; Su, C.; Sorenson, K.; Elhag, D.; Rathi, N.; Bakouny, Z.; Agarwal, N.; Zakharia, Y.; Costello, BA.; McKay, RR.; Narayan, V.; Alva, A.; McGregor, BA.; Gao, X.; McDermott, DF.; Choueiri, TK.: Evaluation of the Safety and Efficacy of Immunotherapy Rechallenge in Patients With Renal Cell Carcinoma JAMA Oncology 6 (10): 1606-1610,2020.
Narayan, V.; Thompson, EW.; Demissei, B.; Ho, JE.; Januzzi, JL.; Ky, B.: Mechanistic Biomarkers Informative of Both Cancer and Cardiovascular Disease J Am Coll Cardiology 75 (21): 2726-2737,2020.
Chanzá, NM.; Xie, W.; Bilen, MA.; Dzimitrowicz, H.; Burkart, J.; Geynisman, DM.; Balakrishnan, A.; Bowman, IA.; Jain, R.; Stadler, W.; Zakharia, Y.; Narayan, V.; Beuselinck, B.; McKay, R.; Tripathi, A.; Pachynski, R.; Hahn, AW.; Hsu, J.; Shah, SA.; Lam, ET.; Rose, TL.; Mega, AE.; Vogelzang, N.; Harrison, MR.; Mortazavi, A.; Plimack, ER.; Vaishampayan, U.; Hammers, H.; George, S.; Haas, N.; Agarwal, N.; Pal, SK.; Srinivas, S.; Carneiro, BA.; Heng, D.; Bosse, D.; Choueiri, T.; Harshman, LC.: Cabozantinib in advanced non-clear cell renal carcinoma: a multicenter retrospective cohort analysis Lancet Oncol 20 (4): 581-590,2019.
Narayan, V.; Ky, B.: Common Cardiovascular Complications of Cancer Therapy: Epidemiology, Risk Prediction, and Prevention Annu Rev Med 69 (1): 97-111,2018.
Finkelman, BS., Putt, M., Wang, T., Wang, L., Narayan, H., Domchek, S., DeMichele, A., Fox, K., Matro, J., Shah, P., Clark, A., Bradbury, A., Narayan, V., Carver, J., Tang, WH., Ky, B.: Arginine-Nitric Oxide Metabolites and Cardiac Dysfunction in Patients with Breast Cancer J Am Coll Cardiology 70 (2): 152-162,2017.
Narayan, V.; Vapiwala, N.; Mick, R.; Subramanian, P.; Christodouleas, J.; Bekelman, J.; Deville, C.; Rajendran, R.; Haas, NB.: Phase I Trial of Everolimus and Radiation Therapy for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy Int J Radiat Oncol Biol Phys 97 (2): 355-361,2017.
Demissei, B.; Finkelman, B.; Hubbard, RA.; Zhang, L.; Smith, AM.; Sheline, K.; McDonald, C.; Narayan, HK.; Narayan, V.; Waxman, AJ.; Domchek, S.; DeMichele, A.; Shah, P.; Clark, A.; Bradbury, A.; Carver, J.; Upshaw, J.; Armenian, SH.; Liu, P.; Ky, B.: Detailed Phenotyping Reveals Distinct Trajectories of Cardiovascular Function and Symptoms with Exposure to Modern Breast Cancer Therapy Cancer
125 (16): 2762-2771,2019.
Mohiuddin, J.; Narayan, V.; Venigalla, S.; Vapiwala, N.: Variations in patterns of concurrent androgen deprivation therapy use based on dose escalation with external beam radiotherapy vs. brachytherapy boost for prostate cancer Brachytherapy
18 (3): 322-331,2019.
Narayan, V.; Gunnarsson, O.; Hwang, WT.; Nathanson, KL.; Stadtmauer, EA.; Vaughn, DJ.: Risk-Stratified Initial Salvage Therapy for Relapsed or Refractory Metastatic Germ Cell Tumor Clin Genitourin Cancer 14 (6): 524-529,2016.
Narayan, V., Haas, N.: Axitinib in the treatment of renal cell carcinoma: patient selection and perspectives Int J Nephrol 9 : 65-72,2016.
Debanjan Pain, Samuel U. Takvorian, Vivek Narayan: Disparities in Clinical Care and Research in Renal Cell Carcinoma Kidney Cancer 6 (3): 147-157,2022.
Barrett, M.; Wilcox, NS.; Huang, A.; Levy, R.; Demissei, B.; Narayan, V.; Ky, B.: Bearing Allostatic Load: Insights into a More Equitable Future Within Cardio-Oncology Trends Mol Medic 28 (12): 1040-1049,2022.
Lee, DJ.; Hausler, R.; Le, AN.; Kelly, G.; Powers, J.; Ding, J.; Feld, E.; Desai, H.; Morrison, C.; Doucette, A.; Gabriel, P.; Regeneron Genetics Center; Judy, RL.; Weaver, J.; Kember, R.; Damrauer, SM.; Rader, DJ.; Domchek, SM.; Narayan, V.; Schwartz, LE.; Maxwell, KN.: Association of inherited mutations in DNA repair genes with localized prostate cancer
Eur Urol
81 (6): 559-567,2022.
Hamilton, JG.; Symecko, H.; Spielman, K.; Breen, K.; Mueller, R.; Catchings, A.; Trottier, M.; Salo-Mullen, EE.; Shah, I.; Arutyunova, A.; Batson, M.; Gebert, R.; Pundock, S.; Schofield, E.; Offit, K.; Stadler, ZK.; Cadoo, K.; Carlo, MI.; Narayan, V.; Reiss, KA.; Robson, ME.; Domchek, SM.: Uptake and acceptability of a mainstreaming model of hereditary cancer multigene panel testing among patients with ovarian, pancreatic, and prostate cancer Genet Med
23 (11): 2105-2113,2021.
Morris, MJ.; Rowe, S.; Gorin, MA.; Saperstein, L.; Pouliot, F.; Josephson, DY.; Wong, JYC.; Pantel, AR.; Cho, SY.; Gage, KL.; Piert, MR.; Iagaru, A.; Pollard, JH.; Wong, V.; Jensen, J.; Lin, T.; Stambler, N.; Carroll, P.; Siegel, BA.; Wibmer, AG.; Durack, JC.; Solomon, SB.; Harb, R.; Pucar, D.; Sprenkle, P.; Beauregard, JM.; Beaulieu, A.; Buteau, FA.; Yamauchi, D.; Glaser, S.; Dorff, T.; Narayan, V.; Fillare, MA.; Schubert, E.; Cooley, G.; Morris, ZS.; Langeland, M.; Pow-Sang, JM.; Yamoah, K.; Alva, A.; Reichert, Z.; Spratt, D.; Davidzon, G.; Aparici, CM.; Moradi, F.; Tracy, C.; Behr, S.; Nguyen, HG.; Simko, JP.; Jennings, JW.; Michalski, JM.; Pachynski, RK.: Diagnostic Performance of 18 F-DCFPyL-PET/CT in Men with Biochemically Recurrent Prostate Cancer: Results from the CONDOR Phase 3, Multicenter Study Clin Cancer Res 27 (13): 3674-3682,2021.
Narayan, V.; Morgans, AK.: Duration of Androgen Deprivation Therapy and Cardiovascular Fitness: Right Patient, Right Therapy, Right Time JACC: CardioOncol 2 (4): 564-566,2020.
Demissei BG; Finkelman B; Hubbard RA; Smith AM; Narayan HK; Narayan V; Shah P; Waxman AJ; Domchek SM; Ky B.: Cardiovascular Function Phenotypes in Response to Cardiotoxic Breast Cancer Therapy J Am Coll Cardiology 73 (2): 248-249,2019.
Zhang, KW; Finkelman, BS; Gulati, G; Narayan, HK; Upshaw, J; Narayan, V; Plappert, T; Englefield, V; Smith, AM; Zhang, C; Hundley, WG; Ky B.: Abnormalities in 3-Dimensional Left Ventricular Mechanics With Anthracycline Chemotherapy Are Associated With Systolic and Diastolic Dysfunction JACC Cardiovasc Imaging
11 (8): 1059-1068,2018.
Narayan, V.; Hwang, WT.; Lal, P.; Rosen, M.; Gallagher, M.; O'Dwyer, P.; Vaughn, DJ.: Cyclin-Dependent Kinase 4/6 Inhibition for the Treatment of Mature Teratoma: Long-term Follow-up of a Phase II Study Clin Genitourin Cancer 14 (6): 504-510,2016.
Narayan, V.; Deshpande, C.; Bermudez, CA.; Golato, JM.; Lee, J.; Diamond, J.; Vaughn, DJ.: Bilateral Lung Transplantation for Bleomycin-Associated Lung Injury Oncologist 22 (5): 620-622,2017.
Narayan, V.; Mamtani, R.; Keefe, S.; Guzzo, T.; Malkowicz, SB.; Vaughn, DJ.: A Phase II Study of Cisplatin, Gemcitabine, and Lapatinib as Neoadjuvant Therapy for Muscle-Invasive Bladder Cancer Cancer Res Treat 48 (3): 1084-91,2016.
Marar, M.; Long, Q.; Mamtani, R.; Narayan, V.; Vapiwala, N.; Parikh, RB.: Outcomes Among African American and Non-Hispanic White Men With Metastatic Castration-Resistant Prostate Cancer With First-Line Abiraterone JAMA Netw Open
5 (1): e2142093,2022.
Bratslavsky, G.; Mendhiratta, N.; Daneshvar, M.; Brugarolas, J.; Ball, MW.; Metwalli, A.; Nathanson, KL.; Pierorazio, P.; Boris, RS.; Singer, EA.; Carlo, MI.; Daly, MB.; Henske, EP.; Hyatt, C.; Middleton, L.; Morris, G.; Jeong, A.; Narayan, V.; Rathmell, WK.; Vaishampayan, U.; Lee, BL.; Battle, D.; Hall, MJ.; Hafez, K.; Jewett, MAS.; Karamboulas, C.; Pal, SK.; Hakimi, AA.; Kutikov, A.; Iliopoulos, O.: Linehan, WM.; Jonasch, E.: Genetic Risk Assessment for Hereditary Renal Cell Carcinoma: Clinical Consensus Statement Cancer
127 (21): 3957-3966,2021.
Feld, E.; Harton, J.; Meropol, NJ.; Adamson, BJS.; Cohen, A.; Parikh, RB.; Galsky, MD.; Narayan, V.; Christodouleas, J.; Vaughn, DJ.; Hubbard, RA.; Mamtani, R.: Effectiveness of First-line Immune Checkpoint Blockade Versus Carboplatin-based Chemotherapy for Metastatic Urothelial Cancer Eur Urol 76 (4): 524-532,2019.
Narayan, V.; Vaughn, DJ.; Ky, B.: Cardiovascular Toxicities of Therapy for Genitourinary Malignancies Urologic Oncology: Seminars and Original Investigations 38 (3): 121-128,2020.
Narayan, V.; Gladney, W.; Plesa, G.; Vapiwala, N.; Carpenter, E.; Maude, SL.; Lal, P.; Lacey, S.; Melenhorst, J.; Sebro, R.; Farwell, M.; Hwang, WT.; Moniak, M.; Gilmore, J.; Lledo, L.; Dengel, K.; Marshall, A.; Coughlin, C.; June, CH.; Haas, NB.: A phase I clinical trial of PSMA-directed/TGFβ-insensitive CAR-T cells in metastatic castration-resistant prostate cancer American Society of Clinical Oncology Genitourinary Cancers Symposium, San Francisco, CA J Clin Oncol 37 (suppl 7S; abstr TPS347): 2019.
Narayan, V.; Vaughn, D.: Pharmacokinetic and toxicity considerations in the use of neoadjuvant chemotherapy for bladder cancer Expert Opin Drug Metab Toxicol 11 (5): 731-42,2015.
Parikh, RB.; Gallo, JJ.; Wong. Y.; Robinson, KW.; Cashy, JP.; Narayan, V.; Jayadevappa, R.; Chhatre, S.: Long-term depression incidence and associated mortality among African American and White prostate cancer survivors Cancer 127 ((18)): 3476-3485,2021.
Osterman, CK.; Babu, DS.; Geynisman, D.; Lewis, B.; Somerd, RA.; Balar, AV.; Zibelman, MR.; Guancial, EA.; Antinori, G.; Yu, S.; Narayan, V.; Guzzo, TJ.; Plimack, ER.; Vaughn, DJ.; Fung, C.; Mamtani, R.: Efficacy of Split Schedule Versus Conventional Schedule Neoadjuvant Cisplatin‐Based Chemotherapy for Muscle‐Invasive Bladder Cancer Oncologist
24 (5): 688-90,2019.
Osterman, CK.; Alanzi, J.; Lewis, JD.; Kaufman, EL.; Narayan, V.; Boursi, B.; Vajravelu, RK.; Scott, FI.; Malkowicz, SB.; Mamtani, R.: Association Between Symptomatic Versus Asymptomatic Recurrence and Survival in Bladder Cancer Clin Genitourin Cancer 16 (3): 235-239,2018.
Catino, AB; Hubbard, RA; Chirinos, JA; Townsend, R; Keefe, S; Haas, NB; Puzanov, I; Fang, JC; Agarwal, N; Hyman, D; Smith, AM; Gordon, M; Plappert, T; Englefield, V; Narayan, V; Ewer, S; ElAmm, C; Lenihan, D; Ky, B.: Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma Circ Heart Fail 11 (3): e004408,2018.
Hahn, VS.; Zhang, KW.; Sun, L.; Narayan, V.; Lenihan, DJ.; Ky, B.: Heart Failure With Targeted Cancer Therapies: Mechanisms and Cardioprotection Circ Res 128 (10): 1576-1593,2021.
Li, L.; Huang, L.; Vergis, A.; Ye, H.; Bajwa, A.; Narayan, V.; Strieter, R.; Rosin, D.; Okusa, M.: IL-17 produced by neutrophils regulates interferon gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury J Clin Invest 120 (1): 331-42,2010.
Demissei, B.; Hubbard, RA.; Zhang, L.; Smith, AM.; Sheline, K.; McDonald, C.; Narayan, V.; Domchek, SM.; DeMichele, A.; Shah, P.; Clark, AS.; Fox, K.; Matro, J.; Bradbury, AR.; Knollman, H.; Getz, KD.; Armenian, SH.; Januzzi, JL.; Tang, W.; Liu, P.; Ky, B.: Changes in Cardiovascular Biomarkers With Breast Cancer Therapy and Associations With Cardiac Dysfunction J Am Heart Assoc 9 (2): e014708,2020.
Narayan, V.: Metastatic Prostate Cancer Radiation Oncology: A Question Based Review 3rd Edition : 2018.
Hwang, A.; Narayan, V.; Yang, YX.: Type 2 Diabetes Mellitus and Survival in Pancreatic Adenocarcinoma: A Retrospective Cohort Study Cancer 119 (2): 404-10,2013.
Narayan, V.; Jonasch, E.: Systemic Therapy Development in Von Hippel–Lindau Disease: An Outsized Contribution from an Orphan Disease Cancers 14 (21): 5313,2022.
Herrera, CD.; Guerra, CE.; Narayan, V.; Guzzo, TJ.; Mamtani, R.; Lee, DJ.; Tasian, GE.; Talwar, R.: Financial toxicity in prostate cancer survivors: A national cross-sectional assessment of subjective financial burden Urologic Oncology: Seminars and Original Investigations S1078-1439 (22): 00395-7,2022.
Thompson, EW.; Demissei, BG.; Smith, AM.; Brahmbhatt, P.; Wang, J.; Clark, A.; DeMichele, A.; Narayan, V.; Shah, P.; Sun, L.; Lefebvre, B.; Fradley, MG.; Carver, JR.; Tang, WHW.; Ky, B.: Paraoxonase-1 Activity in Breast Cancer Patients Treated With Doxorubicin With or Without Trastuzumab JACC Basic Transl Sci 7 (1): 1-10,2021.
Yu, S.; Le, A.; Feld, E.; Schriver, E.; Gabriel, P.; Doucette, A.; Narayan, V.; Feldman, M.; Schwartz, L.; Maxwell, K.; Mowery, D.: A Natural Language Processing-Assisted Extraction System for Gleason Scores: Development and Usability Study JMIR Cancer 7 (3): e27970,2021.
Demissei, B.; Adusumalli, S.; Hubbard, RA.; Denduluri, S.; Narayan, V.; Clark, A.; Shah, P.; Knollman, H.; Getz, KD.; Aplenc, R.; Carver, JR.; Ky, B.: Cardiology Involvement in Patients With Breast Cancer Treated With Trastuzumab JACC: CardioOncology 2 (2): 179-189,2020.
Chao, HH.; Feld, EK.; Narayan, V.; Sebro, R.; Jones, JA.: Radiation Recall Myositis Following Carboplatin/Docetaxel Chemotherapy Pract Radiat Oncol 10 (1): e50-e52.,2020.
Taku, N.; Narayan, V.; Wang, X.; Vapiwala, N.: Prevalence, predictors, and implications for appropriate use of active surveillance management among black men diagnosed with low-risk prostate cancer Am J Clin Oncol
42 (6): 507-511,2019.
Academic Contact Information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
10th Floor, South Pavilion
Office #10-111
3400 Civic Center Blvd
Philadelphia,
PA
19104
Phone: 215-360-0737
Patient appointments: 800-789-7366