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Timothy H. Lucas, II, MD, PhD Surgeon

Co-Director, Penn Center for Neuro-Engineering and Therapeutics
Director, Translational Neuromodulation Laboratory
Assistant Professor of Neurosurgery

Dr. Lucas is a Penn Medicine employed physician.

Clinical Specialties

Clinical Expertise:

  • Brain Cancer
  • Brain Metastasis
  • Brain Tumors
  • Cancer Clinical Trials
  • Cancer Surgery
  • Cosmetic Laser Surgery
  • Endoscopic Surgery
  • Epilepsy Clinical Trials
  • Microvascular Reconstruction
  • Minimally Invasive Surgery
  • Neuro-Oncology
  • Neurosurgery - Spine
  • Pain Relief Clinical Trials
  • Spinal Cord Cancer
  • Sports Injury
  • Stroke Clinical Trials
  • Traumatic Brain and Spinal Cord Injury Clinical Trials

Description of Clinical Expertise

Epilepsy Surgery
Temporal Lobectomy
Minimally invasive neurosurgery
Laser Neurosurgery
Endoscopic Surgery
Sports Neurosurgery
Cortisectomy / Topectomy
Corpus Callostomy / Functional Disconnection Surgery
Trigeminal neuralgia
Microvascular decompression
Stereotactic and Functional Neurosurgery
Movement Disorder Surgery (Parkinson's Disease, Essential Tremor, Dystonia)
Glioma Surgery (Low Grade, High Grade, Adult, Pediatric)
Insular Lesions
Brain Mapping (Speech, Motor, Sensory; cortical and subcortical)
Extraoperative Brain Mapping
Brain-machine interface / Brain-computer interface
Spine Disorders
Spinal Fusion
Skull base surgery
Brain Plasticity
Eloquent Cortex Lesions (motor, sensory, speech, visual cortex)
Traumatic brain and spine injury

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Florida
Residency: University of Washington Hospital and Clinics
Fellowship: University of Washington Hospital and Clinics
Fellowship: UCSF Medical Center and Hospital


Alpha Omega Alpha, National American Association for the Advancement of Science, International American Association of Neurological Surgeons, International Congress of Neurological Surgeons, International International Society of Electricians and Electrical Engineers (IEEE), International

Hospital Affiliation

Dr. Lucas is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Spinal Cord Stimulation and Mapping

Selected Publications:

Davis Kathryn Adamiak, Nanga Ravi Prakash Reddy, Das Sandhitsu, Chen Stephanie H, Hadar Peter N, Pollard John R, Lucas Timothy H, Shinohara Russell T, Litt Brian, Hariharan Hari, Elliott Mark A, Detre John A, Reddy Ravinder: Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy. Science translational medicine 7 (309): 309ra161,2015.

Chen H Isaac, Bohman Leif-Erik, Emery Lyndsey, Martinez-Lage Maria, Richardson Andrew G, Davis Kathryn A, Pollard John R, Litt Brian, Gausas Roberta E, Lucas Timothy H: Lateral Transorbital Endoscopic Access to the Hippocampus, Amygdala, and Entorhinal Cortex: Initial Clinical Experience. ORL; journal for oto-rhino-laryngology and its related specialties 77 (6): 321-332,2015.

Abdullah Kalil G, Attiah Mark A, Olsen Andrew S, Richardson Andrew, Lucas Timothy H: Reducing surgical site infections following craniotomy: examination of the use of topical vancomycin. Journal of neurosurgery : 1-5,2015.

Liu Xilin, Zhang Milin, Subei Basheer, Richardson Andrew G, Lucas Timothy H, Van der Spiegel Jan: The PennBMBI: Design of a General Purpose Wireless Brain-Machine-Brain Interface System. IEEE transactions on biomedical circuits and systems 9 (2): 248-58,2015.

Azarion Allan A, Wu Jue, Pearce Allison, Krish Veena T, Wagenaar Joost, Chen Weixuan, Zheng Yuanjie, Wang Hongzhi, Lucas Timothy H, Litt Brian, Gee James C, Davis Kathryn A: An open-source automated platform for three-dimensional visualization of subdural electrodes using CT-MRI coregistration. Epilepsia 55 (12): 2028-37,2014.

Wu J, A Azarion, A Pearce, VT Krish, J Waagener, W Chen, Y Zheng, WH Zhi, TH Lucas, J Gee, B Litt and K Davis: An open-source, automated platform for visualizing subdural electrodes using 3D CT-MRI co-registration Epilepsia : 2014.

Chen H Isaac, Attiah Mark, Baltuch Gordon, Smith Douglas H, Hamilton Roy H, Lucas Timothy H: Harnessing plasticity for the treatment of neurosurgical disorders: an overview. World neurosurgery 82 (5): 648-59,2014.

Kuzum D, H Takano, E Shim, JC Reed, H Juul, AG Richardson, J deVries, H Bink, MA Dichter, TH Lucas, DA Coulter, E Cubukeu and B Litt: Transparent, flexible, low-noise graphene electrodes for simultaneous electrophysiology and neuro-imaging Nature Communications 5 (5259): 2014.

Geller Aaron S, Burke John F, Sperling Michael R, Sharan Ashwini D, Litt Brian, Baltuch Gordon H, Lucas Timothy H, Kahana Michael J: Eye closure causes widespread low-frequency power increase and focal gamma attenuation in the human electrocorticogram. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 125 (9): 1764-73,2014.

Burke J, A Sharan, J Evans, K Healey, E Beck, K Davis, T Lucas and M Kahana: Theta and high-frequency mark spontaneous recall of episodic memories Journal of Neuroscience 34 (34): 11355-11365,2014.

Academic Contact Info

3400 Spruce Street
3rd Floor Silverstein

Philadelphia, PA 19104
Phone: (215) 615-0578
Fax: (215) 349-5534
Patient appointments: 800-789-PENN (7366)

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