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Timothy H. Lucas, II, MD, PhD Surgeon

Co-Director, Penn Center for Neuro-Engineering and Therapeutics
Director, Translational Neuromodulation Laboratory
Assistant Professor of Neurosurgery

Dr. Lucas is a Penn Medicine employed physician.

Clinical Specialties

Clinical Expertise:

  • Brain Cancer
  • Brain Metastasis
  • Brain Tumors
  • Cancer Clinical Trials
  • Cancer Surgery
  • Cosmetic Laser Surgery
  • Endoscopic Surgery
  • Epilepsy Clinical Trials
  • Microvascular Reconstructive Surgery
  • Minimally Invasive Surgery
  • Neuro-Oncology
  • Neurosurgery - Spine
  • Pain Relief Clinical Trials
  • Spinal Cord Cancer
  • Sports Injury
  • Stroke Clinical Trials
  • Traumatic Brain and Spinal Cord Injury Clinical Trials

Description of Clinical Expertise

Epilepsy Surgery
Temporal Lobectomy
Minimally invasive neurosurgery
Laser Neurosurgery
Endoscopic Surgery
Sports Neurosurgery
Cortisectomy / Topectomy
Corpus Callostomy / Functional Disconnection Surgery
Trigeminal neuralgia
Microvascular decompression
Stereotactic and Functional Neurosurgery
Movement Disorder Surgery (Parkinson's Disease, Essential Tremor, Dystonia)
Glioma Surgery (Low Grade, High Grade, Adult, Pediatric)
Insular Lesions
Brain Mapping (Speech, Motor, Sensory; cortical and subcortical)
Extraoperative Brain Mapping
Brain-machine interface / Brain-computer interface
Spine Disorders
Spinal Fusion
Skull base surgery
Brain Plasticity
Eloquent Cortex Lesions (motor, sensory, speech, visual cortex)
Traumatic brain and spine injury

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Florida
Residency: University of Washington Hospital and Clinics
Fellowship: University of Washington Hospital and Clinics
Fellowship: UCSF Medical Center and Hospital


Alpha Omega Alpha, National American Association for the Advancement of Science, International American Association of Neurological Surgeons, International American College of Surgeons, National Congress of Neurological Surgeons, International International Society of Electricians and Electrical Engineers (IEEE), International Migratory Functional Neurosurgery Society, National National Institutes of Health / National Institute for Neurological Disorder and Stroke, National National Science Foundation, National Pennsylvania Neurosurgical Society, Local

Hospital Affiliation

Dr. Lucas is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Spinal Cord Stimulation and Mapping

Selected Publications:

Yu, K; Lyu, H; Richardson, AG; Lucas, TH; Kuzum, D: Flexible neural electrode array based-on Porous grapheme for cortical microstimulation and sensing Scientific Reports (accepted with revision) : 2016.

Richardson, Andrew G, Weigand, Pauline K, Sritharan, Srihari Y, Lucas, Timothy H: A chronic neural interface to the macaque dorsal column nuclei Journal of neurophysiology 115 (5): 2255-2264,2016.

Liu, X; Zhang, M; Xiong, T; Richardson, AG; Lucas, TH; Chin, PS; Etienne-Cummings, R; Tran, TD, J Van der Spiegel: A fully integrated wireless compressed sensing neural signal acquisition system for chronic recording and brain machine interface IEEE Trans Biomed Circuits and Systems (in press) : 2016.

Zhang, M; Liu, X; Sacks, J; Richardson, AG; Lucas, TH; Van der Spiegel, J: A virtual trackpad: an electromyography based, wireless, real-time, low-power, embedded hand gesture recognition system using an event driven artificial neural network IEEE Trans Biomed Circuits and Systems : 2016.

Thawani, J; Vaughn, K; Lucas TH: Image guidance and robotics in neurosurgery Robotics in Surgery : 2016.

Abdullah, K; Chen, HI; Lucas, TH: Safety of topical vancomycin powder in neurosurgery Surgical Neurology International (in press) : 2016.

Khambhati, A; Bassett, DS; Oomen, BS; Chen, SH; Lucas TH; Davis, DA; Litt, B: Recurring functional architecture predicts dynamic network interactions during octal and interictal states in human neocortical epilepsy eNeuro (in press) : 2016.

Khambhati, A; Davis, KA; Lucas, TH; Litt, B; Bassett, DS: Virtual cortical resection reveals push-pull network control mechanism preceding seizure evolution Neuron (in press) : 2016.

Liu, Xilin, Zhang, Milin, Richardson, Andrew G, Lucas, Timothy H, Van der Spiegel, Jan: A 12-channel bidirectional neural interface chip with integrated channel-level feature extraction and PID controller for closed-loop operation IEEE Transactions in Biomed Circuits and Systems (in press) : 1-4,2016.

Thawani, Jayesh P, Lucas, Timothy H: Open traumatic brain injury by nail gun resulting in a persistent vegetative state Neurology 86 (14): 1358-1359,2016.

Academic Contact Info

3400 Spruce Street
3rd Floor Silverstein

Philadelphia, PA 19104
Phone: (215) 615-0578
Fax: (215) 349-5534
Patient appointments: 800-789-PENN (7366)

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