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Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
330 South 9th Street
Philadelphia, PA 19107
A facility of Pennsylvania Hospital
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Responses are measured on a scale of 1 to 5 with 5 being the best score.
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Tropea TF, Mak J, Guo MH, Xie SX, Suh E, Rick J, Siderowf A, Weintraub D, Grossman M, Irwin D, Wolk DA, Trojanowski JQ, Van Deerlin V, Chen-Plotkin AS.: TMEM106B Effect on Cognition in Parkinson's Disease and Frontotemporal Dementia. Annals of Neurology : 2019.
Tropea Thomas F, Xie Sharon X, Rick Jacqueline, Chahine Lana M, Dahodwala Nabila, Doshi Jimit, Davatzikos Christos, Shaw Leslie M, Van Deerlin Vivianna, Trojanowski John Q, Weintraub Daniel, Chen-Plotkin Alice S: APOE, thought disorder, and SPARE-AD predict cognitive decline in established Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 33 (2): 289-297,2018.
Tropea Thomas F, Chen-Plotkin Alice S: Unlocking the mystery of biomarkers: A brief introduction, challenges and opportunities in Parkinson Disease. Parkinsonism & related disorders 46 Suppl 1 : S15-S18,2018.
Martínez-Rivera A, Hao J, Tropea T F, Giordano T P, Kosovsky M, Rice R C, Lee A, Huganir R L, Striessnig J, Addy N A, Han S, Rajadhyaksha A M: Enhancing VTA Ca1.3 L-type Ca channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. Molecular psychiatry 22 (12): 1735-1745,2017.
Schierberl Kathryn, Hao Jin, Tropea Thomas F, Ra Stephen, Giordano Thomas P, Xu Qinghao, Garraway Sandra M, Hofmann Franz, Moosmang Sven, Striessnig Joerg, Inturrisi Charles E, Rajadhyaksha Anjali M: Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels. The Journal of neuroscience : the official journal of the Society for Neuroscience 31 (38): 13562-75,2011.
Ren Jia-Qian, Jiang Yan, Wang Zhihui, McCarthy Deirdre, Rajadhyaksha Anjali M, Tropea Thomas F, Kosofsky Barry E, Bhide Pradeep G: Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference. Neuropharmacology 60 (2-3): 295-302,2011.
Tropea Thomas F, Kabir Zeeba D, Kaur Gagandeep, Rajadhyaksha Anjali M, Kosofsky Barry E: Enhanced dopamine D1 and BDNF signaling in the adult dorsal striatum but not nucleus accumbens of prenatal cocaine treated mice. Frontiers in psychiatry 2 : 67,2011.
Giordano Thomas P, Tropea Thomas F, Satpute Shirish S, Sinnegger-Brauns Martina J, Striessnig Joerg, Kosofsky Barry E, Rajadhyaksha Anjali M: Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience 30 (50): 17051-62,2010.
Gregus Ann M, Tropea Thomas F, Wang Yanran, Hauck Stefanie C R, Costa Alberto C S, Rajadhyaksha Anjali M, Inturrisi Charles E: Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference. Neuroscience letters 468 (3): 186-9,2010.
Tropea Thomas F, Kosofsky Barry E, Rajadhyaksha Anjali M: Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of neurochemistry 106 (4): 1780-90,2008.
330 South 9th St
Patient appointments: 800-789-7366