Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Not accepting new patients
Recognized by America's Top Doctors for 2017
Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019
Advanced Heart Failure and Transplant Cardiology, 2010
Cardiovascular Disease, 2002
Perelman Center for Advanced Medicine
East Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.
Thomas Cappola is Herbert C. Rorer Professor in Medical Sciences and Chief, Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine. His research aims to uncover heart failure mechanisms in human subjects and to use these insights to improve treatment. This has involved diverse approaches, including applied genomics, population science, laboratory studies, and clinical trials. He has established and leads a multicenter cohort study of advanced heart failure (Penn Heart Failure Study, PHFS); co-loads a multicenter consortium for human myocardial transcriptomics and systems genetics (Myocardial Applied Genomics Network, MAGNet); serves as a Principal Investigator on the NHLBI Heart Failure Clinical Research Network; and is a contributing member of numerous international genomics consortia. Within the Cardiovascular Division, he has established collaborative leadership to create programs integrating science and clinical care, and has used these as a platform for research and training. In his clinical role, he treats patients with advanced heart failure on the inpatient and outpatient heart failure/transplant service.
Patel N, Russell GK, Musunuru K, Gutierrez OM, Halade G, Kain V, Prabhu SD, Margulies KB, Cappola TP, Arora G, Wang TJ, Arora P: Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial Circulation Research : [Epub ahead of print],2019.
Lyle MA, Iyer SR, Redfield MM, Reddy YNV, Felker GM, Cappola TP, Hernandez AF, Scott CG, Burnett JC Jr, Pereira NL: Circulating Neprilysin in Patients with Heart Failure with Preserved Ejection Fraction JACC Heart Fail
19 : [Epub ahead of print],2019.
Celik S, Karbalaei Sadegh M, Morley M, Roselli C, Ellinor PT, Cappola T, Smith JG, Gidlof O: Antisense regulation of atrial natriuretic peptide expression
JCI Insight : 130978,2019.
Haggerty CM, Damrauer SM, Levin MG, Birtwell D, Carey DJ, Golden AM, Hartzel DN, Hu Y, Judy R, Kelly MA, Kember RL, Lester Kirchner H, Leader JB, Liang L, McDermott-Roe C, Babu A, Morley M, Nealy Z, Person TN, Pulenthiran A, Small A, Smelser DT, Stahl RC, Sturm AC, Williams H, Baras A, Margulies KB, Cappola TP, Dewey FE, Verma A, Zhang X, Correa A, Hall ME, Wilson JG, Ritchie MD, Rader DJ, Murray MF, Fornwalt BK, Arany Z.: Genomics-first evaluation of heart disease associated with titin-truncating variants. Circulation 140 (1): 42-50,2019.
Cordero P, Parikh V, Chin E, Erbilgin A, Gloudemans M, Ching S, Chang ACH, Huang Y, Smith K, Dewey F, Zaleta-Rivera K, Morley M, Brandimarto J, Glazer N, Waggott D, Pavlovic A, Moravec C, Zhao M, Tang WHW, Skreen J, Malloy C, Hannenhalli S, Li H, Ritter S, Li M, Bernstein D, Connolly A, Hakonarson H, Lusis A, Marguiles KB, Depaoli-Roach A, Montgomery S, Wheeler M, Cappola TP, Ashley: Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure-overload heart failure Nat Commun 10 (1): 2760,2019.
Michael MP, Wang X, Hu R; Brandimarto J, Tucker, NR, Felix JF, Smith NL, van der Harst P, Ellinor PT, Margulies KB, Musunuru K, Cappola TP: Cardioprotective effects of MTSS1 enhancer variants Circulation 139 (17): 2073–2076,2019.
Kannan L, Shaw PA, Morley MP, Brandimarto J, Fang JC, Sweitzer NK, Cappola TP, Cappola AR: Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes Circ Heart Fail. 2018 Dec;11(12) 11 (12): e005266,2018.
Levin MG, Kember RL, Judy R, Birtwell D, Williams H, Arany Z, Giri J, Guerraty M, Cappola T; Regeneron Genetics Center, Chen J, Rader DJ, Damrauer SM: Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization Circ Genom Precis Med 11 (11): e002352,2018.
Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP…Lubitz SA, Lunetta KL, Ellinor PT.: Multi-ethnic genome-wide association study for atrial fibrillation Nat Genet 50 (9): 1225-1233,2018.
Macri V, Brody JA, Arking DE, Hucker WJ, Yin X, Lin H, Mills RW, Sinner MF, Lubitz SA, Liu CT, Morrison AC, Alonso A, Li N, Fedorov VV, Janssen PM, Bis JC, Heckbert SR, Dolmatova EV, Lumley T, Sitlani CM, Cupples LA, Pulit SL, Newton-Cheh C, Barnard J, Smith JD, Van Wagoner DR, Chung MK, Vlahakes GJ, O'Donnell CJ, Rotter JI, Margulies KB, Morley MP, Cappola TP, Benjamin EJ, Muzny D, Gibbs RA, Jackson RD, Magnani JW, Herndon CN, Rich SS, Psaty BM, Milan DJ, Boerwinkle E, Mohler PJ, Sotoodehnia N, Ellinor PT: Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction Circ Genom Precis Med 11 (5): e001663,2018.
Perelman Center for Advanced MedicineDivision of Cardiovascular Medicine11-113 South Pavilion3400 Civic Center Boulevard
Phone: (215) 662-3140
Patient appointments: 800-789-7366