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Tessa S. Cook, MD, PhD

Tessa S. Cook, MD, PhD Physician

Director, 3-D and Advanced Imaging Laboratory Director, Center for Translational Informatics Assistant Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Cook is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2012

Description of Clinical Expertise

- cardiac CT
- cardiac MRI
- vascular CT
- vascular MRI
- radiography
- thoracoabdominal CT
- ultrasound

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Pennsylvania Hospital
Residency: Hospital of the University of Pennsylvania


American Board of Imaging Informatics, National American Board of Radiology, International American College of Radiology, National American Roentgen Ray Society (ARRS), National Association of University Radiologists (AUR), National Certification Examination Program in Cardiovascular Magnetic Resonance under the Alliance for Physician Certification & Advancement (APCA), International Diagnostic Imaging, International Pennsylvania Radiological Society, Local Philadelphia Roentgen Ray Society, Local Society for Imaging Informatics in Medicine (SIIM), International SPIE, International United Kingdom National Institute for Health Research, International

Hospital Affiliation

Dr. Cook is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

- imaging informatics
- radiation dose monitoring
- radiation dose reduction
- follow-up tracking
- mobile apps for radiology education

Selected Publications:

TS Cook: #RADxx blog #RADxx blog : 2018.

Cook TS: Large datasets, logistics, sharing, and workflow in screening British Journal of Radiology in press : 2018.

AM Wnorowski, TS Cook, D Lalevic, JE Langer, HM Zafar: Outcome of liver lesions indeterminate for malignancy on ultrasound: the role of patient age, risk status, and lesion echogenicity Abdominal Radiology in press online : 1-10,2018.

Lauren F Comisar, Hanna M Zafar MD MHS, Darco Lalevic BS, Charles E Kahn Jr. MD MS, Mitchell Schnall MD PhD, Tessa S Cook MD PhD: Frequency of Imaging Findings Indeterminate or Suspicious for Malignancy at Three Hospital Types within an Academic Health System AUR 2018 : 2018.

McDonald JS, McDonald RJ, Davenport MS, Jaffe TA, Cook TS, Kallmes DF, Kotsenas AL: Gender and Radiology Publication Productivity: An Examination of Academic Faculty From Four Health Systems in the United States J Am Coll Rad 14 (8): 1100-18,2018.

J Chen, D Lalevic, X Zhang, J Wildenberg, SO Trerotola, TS Cook: Development of an automated system for quality assurance of image-guided biopsies Journal of Vascular and Interventional Radiology 29 (4): S67,2018.

GJ Liao, JM Liao, D Lalevic, TS Cook, HM Zafar: Time to Talk: Can Radiologists Improve Follow-Up of Abdominal Imaging Findings Indeterminate for Malignancy by Initiating Verbal Communication? J Am Coll Rad in press : 2018.

GJ Liao, JM Liao, TS Cook: Geographic Patterns of Radiology Referrals in the United States: A Descriptive Network Analysis J Am Coll Rad online : 2018.

Jeffrey Duda, Emmanuel Botzolakis, Po-Hao Chen, Suyash Mohan, Ilya Nasrallah, Andreas Rauschecker, Jeffrey Rudie, R Nick Bryan, James Gee, Tessa Cook: Bayesian network interface for assisting radiology interpretation and education Proc. SPIE Medical Imaging 2018: Imaging Informatics for Healthcare, Research, and Applications 10579 : 105790S,2018.

Chen P, Roth H, Galperin-Aizenberg M, Ruutiainen AT, Gefter W, Cook TS: Improving Abnormality Detection on Chest Radiography Using Game-Like Reinforcement Mechanics Academic Radiology 24 (11): 1428-1435,2017.

Academic Contact Info

Hospital of University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-3431
Patient appointments: 800-789-7366 (PENN)