Susan J. Mandel, MD, MPH
Endocrinology
Accepting new patients
Sees patients age 18 and up
Penn Endocrinology Perelman
Make an appointmentCall 215-662-2300
Penn Medicine Provider

About me

  • Chief, Endocrinology, Diabetes and Metabolism
  • Sylvan H. Eisman Professor of Medicine II
  • Professor of Medicine in Radiology

Education and training

  • Medical School: Columbia University
  • Residency: NewYork–Presbyterian Hospital
  • Fellowship: Mass General Brigham Healthcare Center - Chestnut Hill

What my patients think about me

Average Rating

386 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

January 2026
very good communication
December 2025
provider is very knowledgeable and has a great bedside manner
December 2025
i have been seeing her for 19 years and she has been on top of my endocrine issue, assessing me every 6 months.
December 2025
dr.mandel was very thorough during my visit with her. dr.mandel spent time with me going into detail regarding my results for that reason i'm truly grateful.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Mandel is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Biller BMK, Garg N, Mandel SJ, McHan L, Theodorou A, Weber TJ. Clinical Pearls From JCEM Case Reports: ENDO 2025 , JCEM Case Rep, 3: 2025,luaf225

Haddad RI, Bischoff L, Applewhite M, Bernet V, Blomain E, Brito M, Busaidy NL, Campbell M, DeLozier O, Duh QY, Ehya H, Grady E, Guo T, Haymart M, Hunt JP, Kandeel F, Kotwal A, Lamonica DM, Lorch J, Mandel SJ, Markovina S, Mydlarz W, Nabell L, Raeburn CD, Rezaee R, Ridge JA, Ritter H, Roth MY, Salgado SA, Scheri RP, Shah JP, Sipos JA, Sippel R, Sturgeon C, Wirth LJ, Wong RJ, Worden F, Yeh MW, Darlow S, Cassara CJ, Sliker B. NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025 , J Natl Compr Canc Netw: 2025

Nachum S, Tondi Resta I, Baloch Z, Mandel SJ. Thyroid Nodules with Indeterminate Cytology and Negative Molecular Profile: Prevalence of Malignancy and Practice Paradigms for Surveillance , Thyroid: 2025

Ginzberg SP, Sharpe J, Passman JE, Amjad W, Wirtalla CJ, Soegaard Ballester, JM, Finn CB, Mandel SJ, Kelz RR, Wachtel H. Revisiting the Relationship Between Tumor Size and Risk in Well-Differentiated Thyroid Cance , Thyroid, 34(8): 2024.,980-989

Alexis M, Ginzberg SP, Soegaard Ballester JM, Mandel SJ, Langer JE, Kelz RR, Wachtel H. Assessing the Frequency of Deferrable Thyroid Nodule Biopsies to De- escalate Low-Value Care , Endocr Pract., 30(4): 2024,305-310

Grani G, Del Gatto V, Cantisani V, Mandel SJ, Durante C. A Reappraisal of Suspicious Sonographic Features of Thyroid Nodules: Shape Is Not an Independent Predictor of Malignancy , J Clin Endocrinol Metab, 108: 2023,e816-e822

Durante C, Hegedüs L, Na DG, Papini E, Sipos JA, Baek JH, Frasoldati A, Grani G, Grant E, Horvath E, Hoang JK, Mandel SJ, Middleton WD, Ngu R, Orloff LA, Shin JH, Trimboli P, Yoon JH, Tessler FN. International Expert Consensus on US Lexicon for Thyroid Nodules , Radiology: 2023

Andrianus S, Gubbiotti MA, Mandel SJ, Nikiforov YE, Baloch Z. Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens , Diagn Cytopathol: 2023

Ginzberg SP, Soegaard Ballester JM, Wirtalla CJ, Pryma DA, Mandel SJ, Kelz RR, Wachtel H. Insurance-Based Disparities in Guideline-Concordant Thyroid Cancer Care in the Era of De-escalation , J Surg Res: 2023

Chou R, Dana T, Mayson SE, Cibas ES, Durante C, Solórzano CC, Mandel SJ, Orloff LA. Ultrasound Follow-Up of Benign Thyroid Nodules: A Scoping Review , Thyroid: 2023