Description of Research Expertise:
Breast cancer genetics
Breast cancer prevention and screening
Breast cancer immunotherapy clinical trials
Selected Publications:
Max Wattenberg, Daniella Asch, Shun Yu, Peter O’Dwyer, Susan Domchek, Katherine Nathanson, Mark Rosen, Gregory L Beatty, Evan Siegelman, and Kim Reiss: Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation
British Journal of Cancer : 2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR.: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med. 7 (9): e898,2019.
Jada G. Hamilton, PhD, MPH; Jessica M. Long, MS, LCG; Amanda C. Brandt, MS, LC; Jamie Brower, MS; Heather Symecko, MPH; Erin E. Salo-Mullen, MS, MPH, CGC; Stephanie N. Christian, MPH; Tricia Harstad, MA; Fergus J. Couch, PhD; Judy E. Garber, MD, MPH; Kenneth Offit, MD, MPH; Mark E. Robson, MD; and Susan M. Domchek, MD: Patients’ Medical and Psychosocial Experiences After Detection of a CDH1 Variant With Multigene Panel Testing JCO Precision Oncology : 2019.
Domchek SM, Robson ME.: Update on Genetic Testing in Gynecologic Cancer J Clin Oncology : 2019.
Domchek SM, Robson M.: Broadening Criteria for BRCA1/2 evaluation: Placing the USPSTF Recommendation in Context JAMA : 2019.
Robson M, Ruddy KJ, Im SA, Senkus E, Xu B, Domchek SM, Masuda N, Li W, Tung N, Armstrong A, Delaloge S, Bannister W, Goessl C, Degboe A, Hettle R, Conte P.: Patient-reported outcomes in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer receiving olaparib versus chemotherapy in the OlympiAD trial. Eur J Cancer : 20-30,2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR.: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med : 2019.
Shun Yu, MD1, 2; Parul Agarwal, MD1; Ronac Mamtani, MD1, 2; Heather Symecko, MPH2; Kelsey Spielman, MS2; Mark O’Hara, MD1, 2; Peter J. O’Dwyer, MD1, 2; Charles Schneider, MD1, 2; Ursina Teitelbaum, MD1, 2; Katherine L. Nathanson, MD1, 2; Susan M. Domchek, MD1, 2; and Kim A. Reiss, MD1, 2: Retrospective Survival Analysis of Patients With Resected Pancreatic Ductal Adenocarcinoma and a Germline BRCA or PALB2 Mutation JCO Precision Oncology : 2019.
Clark DF, Maxwell KN, Powers J, Lieberman DB, Ebrahimzadeh J, Long JM, McKenna D, Shah P, Bradbury A, Morrissette JJD, Nathanson KL, Domchek SM.: Identification and Confirmation of Potentially Actionable Germline Mutations in Tumor-Only Genomic Sequencing JCO Precision Oncology : 2019.
Qian F, Rookus MA, Leslie G, Risch HA, Greene MH, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Domchek SM, Tung N, van Asperen CJ, van Engelen K, van Rensburg EJ, Venat-Bouvet L, Vierstraete J, Wagner G, Walker L, Weitzel JN, Yannoukakos D; KConFab Investigators; HEBON Investigators; GEMO Study Collaborators; EMBRACE Collaborators, Antoniou AC, Goldgar DE, Olopade OI, Chenevix-Trench G, Rebbeck TR, Huo D; CIMBA.: Mendelian randomization study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. . Br J Cancer : 2019.