Description of Research Expertise:
Breast cancer genetics
Breast cancer prevention and screening
Breast cancer immunotherapy clinical trials
Selected Publications:
Kristeleit RS, Oaknin A, Ray-Coquard I, Leary A, Balmaña J, Drew Y, Oza AM, Shapira-Frommer R, Domchek SM, Cameron T, Maloney L, Goble S, Lorusso D, Ledermann JA, McNeish IA.: Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety. Int J Gynecol Cancer. 29 (9): 1396-1404,2019.
Robson M, Domchek S.: Broad Application of Multigene Panel Testing for Breast Cancer Susceptibility-Pandora's Box Is Opening Wider. JAMA Oncol : 2019.
Powers J, Spielman K, Mueller R, Batson M, Pundock S, Arutyunova A, Symecko H, Domchek S.: Genetic counseling and oncology: proposed approaches for collaborative care delivery. Can J Urol 26 (552): 57-59,2019.
Page EC, Bancroft EK, Brook MN, Assel M, Hassan Al Battat M, Thomas S, Taylor N, Chamberlain A, Pope J, Raghallaigh HN, ...Domchek S, ...Moynihan C, Rennert G, Suri M, Wilson P, Dudderidge T; IMPACT Study Collaborators, Offman J, Kote-Jarai Z, Vickers A, Lilja H, Eeles RA.: Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers. Eur Urol : 2019.
Upshaw JN, Finkelman B, Hubbard RA, Smith AM, Narayan HK, Arndt L, Domchek S, DeMichele A, Fox K, Shah P, Clark A, Bradbury A, Matro J, Adusumalli S, Carver JR, Ky B.: Comprehensive Assessment of Changes in Left Ventricular Diastolic Function With Contemporary Breast Cancer Therapy. JACC Cardiovasc Imaging : 2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR.: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med. 7 (9): e898,2019.
Max Wattenberg, Daniella Asch, Shun Yu, Peter O’Dwyer, Susan Domchek, Katherine Nathanson, Mark Rosen, Gregory L Beatty, Evan Siegelman, and Kim Reiss: Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation
British Journal of Cancer : 2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR.: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med : 2019.
Clark DF, Maxwell KN, Powers J, Lieberman DB, Ebrahimzadeh J, Long JM, McKenna D, Shah P, Bradbury A, Morrissette JJD, Nathanson KL, Domchek SM.: Identification and Confirmation of Potentially Actionable Germline Mutations in Tumor-Only Genomic Sequencing JCO Precision Oncology : 2019.
Jada G. Hamilton, PhD, MPH; Jessica M. Long, MS, LCG; Amanda C. Brandt, MS, LC; Jamie Brower, MS; Heather Symecko, MPH; Erin E. Salo-Mullen, MS, MPH, CGC; Stephanie N. Christian, MPH; Tricia Harstad, MA; Fergus J. Couch, PhD; Judy E. Garber, MD, MPH; Kenneth Offit, MD, MPH; Mark E. Robson, MD; and Susan M. Domchek, MD: Patients’ Medical and Psychosocial Experiences After Detection of a CDH1 Variant With Multigene Panel Testing JCO Precision Oncology : 2019.