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Susan M. Domchek, MD

Susan M. Domchek, MD Physician

Director, MacDonald Women’s Cancer Risk Evaluation Center
Executive Director, Basser Center for BRCA
Basser Professor in Oncology

Dr. Domchek is a Penn Medicine employed physician.

About Dr. Susan M. Domchek

Recognized by America's Top Doctors, 2012-14

Recognized by Best Doctors in America 2009-2010, 2011-2012

Recognized in Philadelphia Magazine's Top Docs issues from 2011 to 2013

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties

Specialty:

  • Medical Oncology

Programs & Centers:

Board Certification:

  • Medical Oncology, 2001

Clinical Expertise:

  • Breast Cancer
  • Breast Cancer Genetics

Description of Clinical Expertise

Breast cancer prevention, screening and treatment
Breast cancer genetics

Practice Locations and Appointments

  • Rena Rowan Breast Center

    Abramson Cancer Center Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Harvard Medical School
Residency: Massachusetts General Hospital
Fellowship: Dana-Farber Cancer Institute

Memberships

American Association for Cancer Research (AACR), International American Society of Clinical Oncology, International Eastern Cooperative Oncology Group (PrECOG), National Facing our risk of cancer empowered (FORCE), National Living Beyond Breast Cancer, National National Cancer Institute, National Susan G. Komen for the Cure®, International Triple Negative Breast Cancer Foundation, National

Hospital Affiliation

Dr. Domchek is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Breast cancer genetics
Breast cancer prevention and screening
Breast cancer immunotherapy clinical trials

Selected Publications:

Narayan HK, French B, Khan AM, Plappert T, Hyman D, Bajulaiye A, Domchek S, DeMichele A, Clark A, Matro J, Bradbury A, Fox K, Carver JR, Ky B.: Noninvasive Measures of Ventricular-Arterial Coupling and Circumferential Strain Predict Cancer Therapeutics-Related Cardiac Dysfunction. JACC Cardiovascular Imaging 9 (10): 1131-1141,2016.

Bradbury AR, Patrick-Miller L, Schwartz LA, Egleston BL, Henry-Moss D, Domchek SM, Daly MB, Tuchman L, Moore C, Rauch PK, Shorter R, Karpink K, Sands CB.: Psychosocial Adjustment and Perceived Risk Among Adolescent Girls From Families With BRCA1/2 or Breast Cancer History. Journal of Clinical Oncology 34 (28): 3409-16,2016.

Horick NK, Manful A, Lowery J, Domchek S, Moorman P, Griffin C, Visvanathan K, Isaacs C, Kinney AY, Finkelstein DM.: Physical and psychological health in rare cancer survivors. Journal of Cancer Survivorship : 2016.

Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M, Bjorge L, Blomqvist C, Blot W, Bogdanova N, Bojesen A, Bojesen SE, Bolla MK, Bonanni B, Børresen-Dale AL, Brauch H, Brennan P, Brenner H, Bruinsma F, Brunet J, Buhari SA, Burwinkel B, Butzow R, Buys SS, Cai Q, Caldes T, Campbel: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nature Communications 7 : 12675,2016.

Tung N, Domchek SM, Stadler Z, Nathanson KL, Couch F, Garber JE, Offit K, Robson ME. 2016 Sep;13(9):581-8. doi: 10.1038/nrclinonc.2016.90. Review.: Counselling framework for moderate-penetrance cancer-susceptibility mutations. Nature Reviews Clinical Oncology 13 (9): 581-8,2016.

Domchek S, Kaunitz AM.: Use of systemic hormone therapy in BRCA mutation carriers. Menopause 23 (9): 1026-7,2016.

Balmaña J, Digiovanni L, Gaddam P, Walsh MF, Joseph V, Stadler ZK, Nathanson KL, Garber JE, Couch FJ, Offit K, Robson ME, Domchek SM.: Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing. Journal of Clinical Oncology : 2016.

Maxwell KN, Domchek SM, Nathanson KL, Robson ME.: Population Frequency of Germline BRCA1/2 Mutations. Journal of Clinical Oncology : 2016.

Beer LA, Kossenkov AV, Liu Q, Luning Prak E, Domchek S, Speicher DW, Ky B.: Baseline Immunoglobulin E Levels as a Marker of Doxorubicin and Trastuzumab-Associated Cardiac Dysfunction. Circulation Research : 2016.

Academic Contact Info

Division of Hematology Oncology
10th Floor, South Pavilion
Office #10-107
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 615-3360
Fax: (215) 615-3349
Patient appointments: 800-789-PENN (7366)

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