Description of Research Expertise

The focus of my research group is the role of the pulmonary vasculature and right ventricular function in health and disease. We lead or contribute to epidemiologic studies and clinical trials of pulmonary arterial hypertension, hepatopulmonary syndrome, and lung transplantation. Members of our group also focus on congenital heart disease and pulmonary vascular disease in children.

Selected Publications

Ventetuolo CE, Praestgaard A, Palevsky HI, Klinger JR, Halpern SD, Kawut SM: Sex and hemodynamics in pulmonary arterial hypertension Eur Respir J 43 (2): 523-30,2014.

Goncharov DA, Kudryashova TV, Ziai H, Ihida-Stansbury K, DeLisser H, Krymskaya VP, Tuder RM, Kawut SM, Goncharova EA.: mTORC2 coordinates pulmonary artery smooth muscle cell metabolism, proliferation and survival in pulmonary arterial hypertension Circulation 129 (8): 864-74,2014.

Whitman I, Patel VV, Soliman EZ, Bluemke DA, Praestgaard A, Jain A, Herrington D, Lima JAC, Kawut SM: Validity of the surface electrocardiogram criteria for right ventricular hypertrophy: The MESA - Right Ventricle Study JACC (13): 5435,2014.

Smith BM, Kawut SM, Bluemke DA, Basner RC, Gomes AS, Hoffman E, Kalhan R, Lima JAC, Liu C-Y, Michos ED, Prince MR, Rabbani L, Rabinowitz D, Shimbo D, Shea S, Barr RG: Pulmonary hyperinflation and left ventricular mass: The Multi-Ethic Study of Atherosclerosis COPD Study Circulation 127 (14): 1503-11,2013.

Grau M, Graham Barr R, Lima JA, Hoffman EA, Bluemke DA, Carr JJ, Chahal H, Enright PL, Jain A, Prince MR, Kawut SM: Percent emphysema and right ventricular structure and function: The MESA Lung and MESA-RV Studies Chest 144 (1): 136-44,2013.

Fritz J, Blair C, Oudiz R, Dufton C, Olschewski H, Despain D, Gillies H, Kawut SM: Baseline and follow-up six minute walk distance and BNP predict 2-year mortalilty in pulmonary arterial hypertension Chest 143 (2): 315-23,2013.

Kawut SM, Barr RG, Lima JA, Praestgaard A, Johnson WC, Chahal H, Ogunyankin KO, Bristow MR, Kizer JR, Tandri H, Bluemke DA.: Right ventricular structure is associated with the risk of heart failure and cardiovascular death: The MESA-Right Ventricle Study Circulation 126 (14): 1681-8,2012.

Gabler NB, French B, Strom BL, Liu Z, Palevsky HI, Taichman DB, Kawut, SM, Halpern SD: Race and sex differences in response to endothelin receptor antagonists for pulmonary arterial hypertension Chest 141 (1): 20-6,2012.

Gabler NM, French B, Strom BL, Palevsky HI, Taichman DB, Kawut SM, Halpern SD: Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials Circulation 126 (3): 349-56,2012.

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Academic Contact Information

Center for Clinical Epidemiology and Biostatistics
Perelman School of Medicine
9018 Gates Hall
3600 Spruce Street
Philadelphia, PA 19104-6021
Patient appointments: 800-789-7366