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Stephen J. Schuster, MD

Stephen J. Schuster, MD Physician

Director, Lymphoma Program Director, Lymphoma Translational Research Robert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research

Dr. Schuster is employed by Penn Medicine.

About Dr. Stephen J. Schuster

Recognized by America's Top Doctors 2011 - 2018

Recognized by Best Doctors in America 2005 - 2006, 2011 - 2012, 2015 - 2018

Recognized in Philadelphia magazine's annual Top Docs issues, 2002, and 2010 - 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology

Programs & Centers:

Board Certification:

  • Hematology, 1986
  • Internal Medicine, 1984
  • Medical Oncology, 1989

Clinical Expertise:

  • Adult T-Cell Lymphoma
  • Anaplastic Large Cell Lymphoma
  • Burkitt Lymphoma
  • Chronic Lymphocytic Leukemia
  • CNS Lymphoma
  • Cutaneous B Cell Lymphoma
  • Cutaneous Lymphoma
  • Eosinophilic Granuloma
  • Erdheim-Chester Disease
  • Gray Zone Lymphoma
  • Hematologic Malignancies
  • HIV Lymphoma
  • Hodgkin Lymphoma
  • Immunotherapy
  • Intraocular Lymphoma
  • Large Granular Lymphocytic Leukemia
  • Lymphoblastic Lymphoma
  • Lymphoma Genomics
  • Lymphoma of Bone
  • Mantle Zone Lymphoma
  • Marginal Zone Lymphoma
  • Mediastinal Lymphoma
  • Mucosa-Associated Lymphoid Tissue Lymphoma
  • Non-Hodgkin Lymphoma
  • Peripheral T-Cell Lymphoma
  • Small Lymphocytic Lymphoma
  • Transformed Lymphoma
  • Waldenstrom Macroglobulinemia (WM)
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Jefferson Medical College
Residency: Pennsylvania Hospital
Fellowship: Thomas Jefferson University Hospital
Fellowship: Pennsylvania Hospital


American Association for Cancer Research, National American Society of Clinical Oncology, National American Society of Hematology, National Eastern Cooperative Oncology Group (ECOG), National Leukemia & Lymphoma Society, National

Hospital Affiliation

Dr. Schuster is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Zhang, Qian. Wang, Hong Y. Liu, Xiaobin. Roth, Michael H. Shestov, Alex A. Lee, Seung-Cheol. Jain, Kanika. Soderquist, Craig. Xiong, Qun-Bin. Ruella, Marco. Strauser, Honore. Glickson, Jerry D. Schuster, Stephen J. Ptasznik, Andrzej. Wasik, Mariusz A.: Dynamic Changes in Gene Mutational Landscape With Preservation of Core Mutations in Mantle Cell Lymphoma Cells. Frontiers in Oncology. 9 : 568,2019.

Roeker, Lindsey E. Fox, Christopher P. Eyre, Toby A. Brander, Danielle M. Allan, John N. Schuster, Stephen J. Nabhan, Chadi. Hill, Brian T. Shah, Nirav N. Lansigan, Frederick. Yazdy, Maryam. Cheson, Bruce D. Lamanna, Nicole. Singavi, Arun K. Coombs, Catherine C. Barr, Paul M. Skarbnik, Alan P. Shadman, Mazyar. Ujjani, Chaitra S. Tuncer, Hande H. Winter, Allison M. Rhodes, Joanna. Dorsey, Colleen. Morse, Hannah. Kabel, Charlene. Pagel, John M. Williams, Annalynn M. Jacobs, Ryan. Goy, Andre. Muralikrishnan, Sivraj. Pearson, Laurie. Sitlinger, Andrea. Bailey, Neil. Schuh, Anna. Kirkwood, Amy A. Mato, Anthony R.: Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patients in Routine Clinical Practice. Clinical Cancer Research. 25 (14): 4264-4270,2019.

Bishop, Michael R. Maziarz, Richard T. Waller, Edmund K. Jäger, Ulrich. Westin, Jason R. McGuirk, Joseph P. Fleury, Isabelle. Holte, Harald. Borchmann, Peter. del Corral, Christopher. Tiwari, Ranjan. Anak, Özlem. Awasthi, Rakesh. Pacaud, Lida. Romanov, Vadim V. Schuster, Stephen J.: Tisagenlecleucel in relapsed/refractory diffuse large B-cell lymphoma patients without measurable disease at infusion. Blood Advances. 3 (14): 2230-2236,2019.

Lee, Seung-Cheol. Shestov, Alexander A. Guo, Lili. Zhang, Qian. Roman, Jeffrey C. Liu, Xiaobin. Wang, Hong Y. Pickup, Stephen. Nath, Kavindra. Lu, Pin. Hofbauer, Samuel. Mesaros, Clementina. Wang, Y Lynn. Nelson, David S. Schuster, Stephen J. Blair, Ian A. Glickson, Jerry D. Wasik, Mariusz A.: Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells. Molecular Cancer Research. 17 (6): 1365-1377,2019.

Mato, Anthony R. Roeker, Lindsey E. Eyre, Toby A. Nabhan, Chadi. Lamanna, Nicole. Hill, Brian T. Brander, Danielle M. Barr, Paul M. Lansigan, Frederick. Cheson, Bruce D. Singavi, Arun K. Yazdy, Maryam Sarraf. Shah, Nirav N. Allan, John N. Bhavsar, Erica B. Rhodes, Joanna. Kennard, Kaitlin. Schuster, Stephen J. Williams, AnnaLynn M. Skarbnik, Alan P. Goy, Andre H. Goodfriend, Julie M. Dorsey, Colleen. Coombs, Catherine C. Tuncer, Hande. Ujjani, Chaitra S. Jacobs, Ryan. Winter, Allison M. Pagel, John M. Bailey, Neil. Schuh, Anna. Shadman, Mazyar. Sitlinger, Andrea. Weissbrot, Hanna. Muralikrishnan, Sivraj. Zelenetz, Andrew. Kirkwood, Amy A. Fox, Christopher P.: A retrospective comparison of venetoclax alone or in combination with an anti-CD20 monoclonal antibody in R/R CLL. Blood Advances. 3 (10): 1568-1573,2019.

Rhodes, Joanna M. Schuster, Stephen J. Furth, Emma E. Kennard, Kaitlin. Nasta, Sunita Dwivedy. Svoboda, Jakub. Porter, David L. Mato, Anthony R.: Management of giant cell hepatitis associated with chronic lymphocytic leukemia - a case series and review of the literature. Cancer Biology & Therapy. 20 (8): 1136-1140 ,2019.

Linaburg, Taylor. Davis, Adam R. Khawaja, Muhammad R. Landsburg, Daniel J. Schuster, Stephen J. Svoboda, Jakub. Li, Yimei. Borovskiy, Yuliya., Olson, Timothy S. Bagg, Adam. Hexner, Elizabeth O. Babushok, Daria V.: Hodgkin lymphoma patients have an increased incidence of idiopathic acquired aplastic anemia. PLoS One. 14 (4): e0215021,2019.

Farhan, Ahmed. Chong, Elise A. Schuster, Stephen J. Strelec, Lauren. Nasta, Sunita Dwivedy. Landsburg, Daniel J. Svoboda, Jakub.: Bexarotene in Patients With Peripheral T-cell Lymphomas: Results of a Retrospective Study. Clinical Lymphoma Myeloma Leukemia. 19 (2): 109-115,2019.

Thurner, Lorenz. Hartmann, Sylvia. Fadle, Natalie. Kemele, Maria. Bock, Theresa. Bewarder, Moritz. Regitz, Evi. Neumann, Frank. Nimmesgern, Anna. von Müller, Lutz. Pott, Christiane. Kim, Yoo-Jin. Bohle, Rainer Maria. Wasik, Mariusz. Schuster, Stephen J. Hansmann, Martin-Leo. Preuss, Klaus-Dieter. Pfreundschuh, Michael.: LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting. Leukemia. 33 (1): 148-158,2019.

Schuster, Stephen J. Bishop, Michael R. Tam, Constantine S. Waller, Edmund K. Borchmann, Peter. McGuirk, Joseph P. Jäger, Ulrich. Jaglowski, Samantha. Andreadis, Charalambos. Westin, Jason R. Fleury, Isabelle. Bachanova, Veronika. Foley, S Ronan. Ho, P Joy. Mielke, Stephan. Magenau, John M. Holte, Harald. Pantano, Serafino. Pacaud, Lida B. Awasthi, Rakesh. Chu, Jufen. Anak, Özlem. Salles, Gilles. Maziarz, Richard T for the JULIET Investigators.: Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma. the New England Journal of Medicine. 380 (1): 45-56,2019.

Academic Contact Info

Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-178
3400 Civic Center Blvd

Philadelphia, PA 19104
Phone: (215) 614-1846
Patient appointments: 800-789-7366 (PENN)

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