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Stephen J. Hunt, MD, PhD, DABR

Stephen J. Hunt, MD, PhD, DABR Physician

Co-Director, Penn Image-Guided Interventions (PIGI) Laboratory Assistant Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Hunt is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2013

Clinical Expertise:

  • Chemoembolization
  • Radioembolization
  • Radiofrequency Ablation (RFA)
  • Targeted Molecular Therapy
  • Transjugular Intrahepatic Portosystemic Shunts (TIPS)
  • Uterine Artery Embolization (UAE)
  • Uterine Fibroid Embolization (UFE)
  • Varicocele Embolization
  • Vertebroplasty

Description of Clinical Expertise

lung cancer, liver cancer, kidney cancer, metastatic disease, interventional oncology, oncology, cancer, ablation, cryoablation, microwave ablation, radiofrequency ablation, immunotherapy, radioembolization, chemoembolization

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Stanford University School of Medicine
Residency: Kaiser Foundation Hospital
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Association for Cancer Research, National American Medical Association, National Association of Health Care Journalists, National Cancer Research Institute, National Focused Ultrasound Foundation, National Pennsylvania Medical Society, Local Philadelphia Angio Club, Local Radiological Society of North America, National Society of Interventional Oncology, International Society of Interventional Radiology, National Society of Nuclear Medicine and Molecular Imaging, International University of Pennsylvania Institutional Review Board (IRB) 2, Local

Hospital Affiliation

Dr. Hunt is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

immuno-oncology, interventional oncology, cancer, cancer biology, immunotherapy, cell biology, cell physiology, animal models, translational research, vascular disease, health policy, health economics, GIS, artificial intelligence, ultrasound, AVUS, embolization, ablation, abscopal effect

Selected Publications:

Tischfield DJ, Ackerman D, Noji M, Chen JX, Perkons NR, Nadolski GJ, Hunt SJ, Soulen MC, Furth EE, Gade TP: Establishment of hepatocellular carcinoma patient-derived xenografts from minimally invasive image-guided percutaneous biopsies International Journal of Cancer : 2018.

Perkons NR, Stein EJ, Nwaezeapu C, Wildenberg JC, Saleh K, Itkin-Ofer R, Ackerman D, Soulen MC, Hunt SJ, Nadolski GJ, Gade TP: Electrolytic ablation enables cancer cell targeting through pH modulation Nature Communications Biology 1 (1): 2018.

Huang Y, Shen Q, Bai HX, Wu J, Ma C, Shang Q, Hunt SJ, Karakousis G, Zhang PJ, Zhang Z.: Comparison of Radiofrequency Ablation and Hepatic Resection for the Treatment of Hepatocellular Carcinoma 2 cm or Less. Journal of vascular and interventional radiology : JVIR : 2018.

Nadolski GJ, Hunt SJ, Weber CN, Mohammed M, Pulido S, Noji M, Chisholm A, Gade TPF: Near-Infrared Fluorescence Imaging of Matrix Metalloproteinase 2 Activity as a Biomarker of Vascular Remodeling in Hemodialysis Access Journal of vascular and interventional radiology : JVIR : 1-8,2018.

Cressman Erik N K, Newton Isabel, Larson Andrew C, Woodrum David A, Srimathveeravalli Govind, Borrelli Michael J, Hunt Stephen, Johnson Thor, Kim Charles Y, White Sarah, Pereira Philippe L, Katsanos Konstantinos, Gaba Ron C: State of the Research Enterprise in IR and Recommendations for the Future: Proceedings from the Society of Interventional Radiology Foundation Investigator Development Task Force. Journal of vascular and interventional radiology : JVIR 29 (6): 751-757,2018.

B.M. Currie, J. Chen, D. Ackerman, S. Hunt, G. Nadolski, T. Gade: Point-of-Care Immunoassay for Rapid Analysis of Tumor Biopsies: Proof-of-Principle WCIO 2018 Abstracts : e11,2018.

SJ Hunt: TAEVax: Immunobiologic treatment effects of embolization WCIO 2018 Abstracts : 2018.

E. Alexander, G. Nadolski, M.C. Soulen, W. Stavropoulos, S. Hunt, T. Gade, M. Itkin, S. Shamimi-Noori: Iatrogenic Celiac Axis and Hepatic Artery Dissections During Intra-Arterial Regional Tumor Therapies: A 16-Year Retrospective Review WCIO 2018 Abstracts : e32,2018.

S. McLaughlin, S. Hunt, G. Nadolski, T. Gade: Injectable thermo-sensitive hydrogels as chemoembolic drug delivery agents for interventional applications JVIR 29 (4S): 2018.

P. Habibollahi, S Pourhassan Shamchi, S. Hunt, T. Gade, S. Stavropoulos, M. Soulen, G. Nadolski: Association of radiological complete response following locoregional therapy prior to liver transplantation with long-term outcomes of hepatocellular carcinoma patients JVIR 29 (4S): 2018.

Academic Contact Info

Penn Image-Guided Interventions Laboratory
3400 Spruce Street/1 Silverstein
HUP Department of Radiology

Philadelphia, PA 19104
Phone: (800) 789-7366
Patient appointments: 800-789-7366 (PENN)