Penn Medicine Provider
Cardiology
Sharlene M. Day, MD
5.0
(218)
Accepting new patients
Sees patients age 16 and up
Penn Heart and Vascular Center

About me

  • Director, Translational Research, Division of Cardiovascular Medicine and Cardiovascular Institute
  • Presidential Associate Professor

Education and training

  • Medical School: New York University School of Medicine
  • Residency: University of Michigan Medical Center
  • Fellowship: University of Michigan Medical Center

What my patients think about me

Average Rating
5.0

218 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

June 2025
5.0
5.0
knowledgeable
May 2025
5.0
5.0
easy to understand.
May 2025
5.0
5.0
dr. day had and revieqed.my previous records. she listened and was responsive to my questions.
May 2025
4.0
4.0
she is always friendly and helpful

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Day is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Walsh R, Mazzarotto F, Whiffin N, Buchan R, Midwinter W, Wilk A, Li N, Felkin L, Ingold N, Govind R, Ahm, ad M, Mazaika E, Allouba M, Zhang X, de Marvao A, Day SM, Ashley E, Colan SD, Michels M, Pereira AC, Jacoby D, Ho CY, Thomson KL, Watkins H, Barton PJR, Olivotto, I, Cook SA, Ware JS. Quantitative Approaches to Variant Classification Increase the Yield and Precision of Genetic Testing for Mendelian Diseases: The Case for Hypertrophic Cardiomyopathy. , Genome Medicine, 11(1): 2019,5


Garratt M, Leander D, Pifer K, Herrera J, Day SM, Fiehn O, Brooks S, Miller RA. 17-alpha Estradiol Ameliorates Age-Associated Sarcopenia and Improves Late Life Physical Function in Male Mice But Not in Females or Castrated Males , Aging Cell, 18(2): 2019,e12920


Day SM Nonobstructive Hypertrophic Cardiomyopathy: The High Hanging Fruit. , JAMA Cardiol, 4(3): 2019 ,235-236


Vigneault DM, Yang E, Jensen PJ, Tee MW, Farhad H, Chu L, Noble JA, Day SM, Colan SD, Russell MW, Towbin J, Sherrid MV, Canter CE, Shi L, Ho CY, Bluemke DA Left Ventricular Strain Is Abnormal in Preclinical and Overt Hypertrophic Cardiomyopathy: Cardiac MR Feature Tracking. , Radiology, 290(3): 2019,640-48


Smith ED, Tome J, Mcgrath R, Kumar S, Concannon M, Day SM, Saberi S, Helms AS Exercise hemodynamics in hypertrophic cardiomyopathy identify risk of incident heart failure but not ventricular arrhythmias or sudden cardiac death. , Int J Cardiol, 274: 2019,226-231


O'Leary TS, Snyder J, Sadayappan S, Day SM, Previs MJ MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy. , J Mol Cell Cardiol, 127: 2019,165-173


Glazier AA, Thompson A, Day SM Allelic imbalance and haploinsufficiency in MYBPC3-linked hypertrophic cardiomyopathy. , Pflugers Arch, 471(5): 2019,781-793


Ho CY, Day, SM, Ashley EA, Michels M, Pereira A, Jacoby D, Fox J, Caleshu C, Cirino AL, Ware J, Helms AS, Colan SD, Signorovich J, Green E, Olivotto I Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe). , Circulation, 138(14): 2018,1387-98


Ahmad F, McNally EM, Ackerman MJ, Baty LC, Day SM, Kullo IJ, Madueme PC, Maron MS, Martinez MW, Salberg L, Taylor MR, Wilcox JE. Establishment of Specialized Clinical Cardiovascular Genetics Programs: Recognizing the Need and Meeting the Standards , Circ Genom Precis Med, 12(6): 2019,e000054


Ko C, Arscott P, Saberi S, Concannon M, Day SM, Yashar BM, Helms AS Genetic Testing Impacts the Utility of Prospective Familial Screening in Hypertrophic Cardiomyopathy Through Identification of a Non-Familial Subgroup , Genetics in Medicine, 20(1): 2018,69-75


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