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Serena Cardillo, MD

Serena Cardillo, MD Physician

Assistant Program Director, Internal Medicine Residency Training Program
Associate Professor of Clinical Medicine

Languages spoken:

  • Italian

Dr. Cardillo is a Penn Medicine employed physician.

Clinical Specialties


  • Diabetes, Endocrinology and Metabolism

Programs & Centers:

Board Certification:

  • Endocrinology, Diabetes, & Metabolism, 2006

Clinical Expertise:

  • Cystic Fibrosis-related Diabetes (CFRD)
  • Gestational Diabetes
  • Transplant Diabetes
  • Type 1 Diabetes
  • Type 2 Diabetes

Description of Clinical Expertise

Dr. Cardillo joined the faculty in the Division of Endocrinology, Diabetes, & Metabolism as an Assistant Professor of Medicine in 2006. She completed her undergraduate studies at Johns Hopkins University where she received a B.A. in Behavioral Biology. She received her M.D. from the University of Pennsylvania and completed both a residency in Internal Medicine and a fellowship in Endocrinology at the Hospital of the University of Pennsylvania. Her clinical interests include diabetes management, transplant associated diabetes, pre-diabetes and metabolic syndrome and diabetes in bariatric surgery patients. Her clinical practice is based at the Penn Rodebaugh Diabetes Center.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Diabetes Association, National Endocrine Society, National

Hospital Affiliation

Dr. Cardillo is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Acton EK, Leonard CE, Schutta MH, Cardillo S, Troxel AB, Trotta R, Hennessy S.: Challenges in recruiting subjects to a pilot trial of patient-managed in-hospital insulin BMC Research Notes 8 (1): 523,2015.

Carbonari DM, Saine ME, Newcomb CW, Blak B, Roy JA, Haynes K, Wood J, Gallagher AM, Bhullar H, Cardillo S, Hennessy S, Strom BL, Lo Re V 3rd.: Use of demographic and pharmacy data to identify patients included within both the Clinical Practice Research Datalink (CPRD) and The Health Improvement Network (THIN) Pharmacoepidemiol Drug Safety 24 (9): 999,2015.

Saine ME, Carbonari DM, Newcomb CW, Nezamzadeh MS, Haynes K, Roy JA, Cardillo S, Hennessy S, Holick CN, Esposito DB, Gallagher AM, Bhullar H, Strom BL, Lo Re V 3rd.: Determinants of saxagliptin use among patients with type 2 diabetes mellitus treated with oral anti-diabetic drugs BMC Pharmacol Toxicol. 16 : 8,2015.

Fuerst N, Langelier N, Massaro-Giordano M, Stasi K, Burns C, Cardillo S, Bunya V: Tear osmolarity and dry eye symptoms in diabetics Clinical Ophthalmology : 2014.

Han JH, Crane HM, Bellamy SL, Frank I, Cardillo S, Bisson GP; Centers for AIDS Research Network of Integrated Clinical Systems (CNICS).: HIV infection and glycemic response to newly initiated diabetic medical therapy. AIDS 26 (16): 2087-95,2013.

Jeffrey R Jaeger MD, Carol Chou MD, David J Aizenberg MD, Serena Cardillo MD: Standardized Patients and Communication Coaching in the Evaluation and Remediation of Interns’ Interpersonal Communication Skills Poster Presentation, Department of Medicine Research Day : 2013.

Vincent Lo Re, Kevin Haynes, Eileen E Ming, Jennifer Wood Ives, Laura N Horne, Kimberly Fortier, Dena M Carbonari, Sean Hennessy, Serena Cardillo, Peter P Reese, K Rajender Reddy, David Margolis, Andrea Apter, Stephen E Kimmel, Jason Roy, Cristin P Freeman, Hanieh Razzaghi, Crystal N Holick, Daina B Esposito, Tjeerd-Pieter Van Staa, Harshvinder Bhullar, Brian L Strom: Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies Pharmacoepidemiology and Drug Safety : 2012.

Han JH, Crane HM, Bellamy SL, Frank I, Cardillo S, Bisson GP.: HIV infection and glycemic response to newly initiated diabetic medical therapy 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA : 2012.

Langelier N, Massaro-Giordano Ying GS, Huang J, Burns C, Cardillo S, Bunya V.: Tear Osmolarity and Dry Eye Symptoms in Diabetics and Non-Diabetics Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, FL : 2011.

Iqbal N, Cardillo S, Volger S, Bloeden L, Boston R, Anderson R, Szapary PO: Chromium picolinate does not improve key features of the metabolic syndrome in obese non-diabetic adults Metabolic Syndrome and Related Disorders 7 : 143-50,2009.

Academic Contact Info

University of Pennsylvania Perelman School of Medicine
Division of Endocrinology, Diabetes and Metabolism
Perelman Center for Advanced Medicine, West Pavilion, 4th Floor
3400 Civic Center Blvd.

Philadelphia, PA 19104
Phone: (215) 662-2468
Patient appointments: 800-789-PENN (7366)

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