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Samuel G. Jacobson, MD, PhD

Samuel G. Jacobson, MD, PhD Physician

Director, Center for Hereditary Retinal Degenerations
Director, Retinal Function
Professor of Ophthalmology

Dr. Jacobson is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Ophthalmology

Programs & Centers:

Clinical Expertise:

  • Retinal Degeneration
  • Retinal Gene Therapy

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Superior Vision Benefit Mgmt, Inc (Block Vision)
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Illinois School of Medicine
Residency: Rush University Medical Center
Residency: Massachusetts Eye & Ear Infirmary
Fellowship: Moorfields Eye Hospital
Fellowship: Massachusetts Eye & Ear Infirmary

Memberships

American Academy of Ophthalmology, National Association for Research in Vision and Ophthalmology, International International Society for Clinical Electrophysiology of Vision, International International Society for Eye Research, International

Hospital Affiliation

Dr. Jacobson is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Jin Minghao, Li Songhua, Hu Jane, Jin Heather H, Jacobson Samuel G, Bok Dean: Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins. Advances in experimental medicine and biology 854 : 525-32,2016.

Jacobson Samuel G, Cideciyan Artur V, Huang Wei Chieh, Sumaroka Alexander, Nam Hyun Ju, Sheplock Rebecca, Schwartz Sharon B: Leber Congenital Amaurosis: Genotypes and Retinal Structure Phenotypes. Advances in experimental medicine and biology 854 : 169-75,2016.

Beltran William A, Cideciyan Artur V, Iwabe Simone, Swider Malgorzata, Kosyk Mychajlo S, McDaid Kendra, Martynyuk Inna, Ying Gui-Shuang, Shaffer James, Deng Wen-Tao, Boye Sanford L, Lewin Alfred S, Hauswirth William W, Jacobson Samuel G, Aguirre Gustavo D: Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease. Proceedings of the National Academy of Sciences of the United States of America 112 (43): E5844-53,2015.

Matsui Rodrigo, Cideciyan Artur V, Schwartz Sharon B, Sumaroka Alexander, Roman Alejandro J, Swider Malgorzata, Huang Wei Chieh, Sheplock Rebecca, Jacobson Samuel G: Molecular Heterogeneity Within the Clinical Diagnosis of Pericentral Retinal Degeneration. Investigative ophthalmology & visual science 56 (10): 6007-18,2015.

Cideciyan Artur V, Swider Malgorzata, Schwartz Sharon B, Stone Edwin M, Jacobson Samuel G: Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front. Investigative ophthalmology & visual science 56 (10): 5946-55,2015.

Zhang Ning, Tsybovsky Yaroslav, Kolesnikov Alexander V, Rozanowska Malgorzata, Swider Malgorzata, Schwartz Sharon B, Stone Edwin M, Palczewska Grazyna, Maeda Akiko, Kefalov Vladimir J, Jacobson Samuel G, Cideciyan Artur V, Palczewski Krzysztof: Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations. Human molecular genetics 24 (11): 3220-37,2015.

Jacobson Samuel G, Cideciyan Artur V, Aguirre Gustavo D, Roman Alejandro J, Sumaroka Alexander, Hauswirth William W, Palczewski Krzysztof: Improvement in vision: a new goal for treatment of hereditary retinal degenerations. Expert opinion on orphan drugs 3 (5): 563-575,2015.

Zelinger Lina, Cideciyan Artur V, Kohl Susanne, Schwartz Sharon B, Rosenmann Ada, Eli Dalia, Sumaroka Alexander, Roman Alejandro J, Luo Xunda, Brown Cassondra, Rosin Boris, Blumenfeld Anat, Wissinger Bernd, Jacobson Samuel G, Banin Eyal, Sharon Dror: Genetics and Disease Expression in the CNGA3 Form of Achromatopsia: Steps on the Path to Gene Therapy. Ophthalmology 122 (5): 997-1007,2015.

Cideciyan Artur V, Swider Malgorzata, Jacobson Samuel G: Autofluorescence imaging with near-infrared excitation:normalization by reflectance to reduce signal from choroidal fluorophores. Investigative ophthalmology & visual science 56 (5): 3393-406,2015.

Jacobson Samuel G, Cideciyan Artur V, Roman Alejandro J, Sumaroka Alexander, Schwartz Sharon B, Heon Elise, Hauswirth William W: Improvement and decline in vision with gene therapy in childhood blindness. The New England journal of medicine 372 (20): 1920-6,2015.

View all publications

Academic Contact Info

Scheie Eye Institute
51 North 39th Street
2689

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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