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Samuel G. Jacobson, MD, PhD

Samuel G. Jacobson, MD, PhD Physician

Director, Center for Hereditary Retinal Degenerations Director, Retinal Function Professor of Ophthalmology

Dr. Jacobson is employed by Penn Medicine.

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About Dr. Samuel G. Jacobson

Recognized by Best Doctors in America 2015 – 2018

Clinical Specialties


  • Ophthalmology

Programs & Centers:

Clinical Expertise:

  • Eye Cancer
  • Eye Floaters
  • Inherited Retinal Diseases
  • Leber Congenital Amaurosis (LCA)
  • Macular Degneration
  • Macular Hole
  • Retinal Disorders
  • Uveitis
  • Vitrectomy

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Superior Vision Benefit Mgmt, Inc (Block Vision)
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Illinois School of Medicine
Residency: Rush University Medical Center
Residency: Massachusetts Eye & Ear Infirmary
Fellowship: Moorfields Eye Hospital
Fellowship: Massachusetts Eye & Ear Infirmary


American Academy of Ophthalmology, National Association for Research in Vision and Ophthalmology, International International Society for Clinical Electrophysiology of Vision, International International Society for Eye Research, International

Hospital Affiliation

Dr. Jacobson is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Matsui Rodrigo, McGuigan Iii David B, Gruzensky Michaela L, Aleman Tomas S, Schwartz Sharon B, Sumaroka Alexander, Koenekoop Robert K, Cideciyan Artur V, Jacobson Samuel G: SPATA7: Evolving phenotype from cone-rod dystrophy to retinitis pigmentosa. Ophthalmic genetics 37 (3): 333-8,2016.

Kong Xiangrong, Strauss Rupert W, Michaelides Michel, Cideciyan Artur V, Sahel José-Alain, Muñoz Beatriz, West Sheila, Scholl Hendrik P N: Visual Acuity Loss and Associated Risk Factors in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 2). Ophthalmology : 2016.

Heon Elise, Alabduljalil Talal, Iii David B McGuigan, Cideciyan Artur V, Li Shuning, Chen Shiyi, Jacobson Samuel G: Visual Function and Central Retinal Structure in Choroideremia. Investigative ophthalmology & visual science 57 (9): OCT377-87,2016.

Sumaroka Alexander, Matsui Rodrigo, Cideciyan Artur V, McGuigan David B, Sheplock Rebecca, Schwartz Sharon B, Jacobson Samuel G: Outer Retinal Changes Including the Ellipsoid Zone Band in Usher Syndrome 1B due to MYO7A Mutations. Investigative ophthalmology & visual science 57 (9): OCT253-61,2016.

McGuigan David B, Roman Alejandro J, Cideciyan Artur V, Matsui Rodrigo, Gruzensky Michaela L, Sheplock Rebecca, Jacobson Samuel G: Automated Light- and Dark-Adapted Perimetry for Evaluating Retinitis Pigmentosa: Filling a Need to Accommodate Multicenter Clinical Trials. Investigative ophthalmology & visual science 57 (7): 3118-28,2016.

Cideciyan Artur V, Roman Alejandro J, Jacobson Samuel G, Yan Boyuan, Pascolini Michele, Charng Jason, Pajaro Simone, Nirenberg Sheila: Developing an Outcome Measure With High Luminance for Optogenetics Treatment of Severe Retinal Degenerations and for Gene Therapy of Cone Diseases. Investigative ophthalmology & visual science 57 (7): 3211-21,2016.

Vincent Ajoy, Audo Isabelle, Tavares Erika, Maynes Jason T, Tumber Anupreet, Wright Thomas, Li Shuning, Michiels Christelle, Condroyer Christel, MacDonald Heather, Verdet Robert, Sahel José-Alain, Hamel Christian P, Zeitz Christina, Héon Elise: Biallelic Mutations in GNB3 Cause a Unique Form of Autosomal-Recessive Congenital Stationary Night Blindness. American journal of human genetics 98 (5): 1011-9,2016.

Jacobson Samuel G, Matsui Rodrigo, Sumaroka Alexander, Cideciyan Artur V: Retinal Structure Measurements as Inclusion Criteria for Stem Cell-Based Therapies of Retinal Degenerations. Investigative ophthalmology & visual science 57 (5): ORSFn1-9,2016.

Jin Minghao, Li Songhua, Hu Jane, Jin Heather H, Jacobson Samuel G, Bok Dean: Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins. Advances in experimental medicine and biology 854 : 525-32,2016.

Jacobson Samuel G, Cideciyan Artur V, Huang Wei Chieh, Sumaroka Alexander, Nam Hyun Ju, Sheplock Rebecca, Schwartz Sharon B: Leber Congenital Amaurosis: Genotypes and Retinal Structure Phenotypes. Advances in experimental medicine and biology 854 : 169-75,2016.

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Academic Contact Info

Scheie Eye Institute
51 North 39th Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)

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