Find a Doctor or Practice Location

Are you a referring physician?
I am searching for a
Reset Form
Sami L. Khella, MD

Sami L. Khella, MD Physician

Chief, Department of Neurology, Penn Presbyterian Medical Center Professor of Clinical Neurology

Languages spoken:

  • Arabic
  • French

Dr. Khella is employed by Penn Medicine.

About Dr. Sami L. Khella

Recognized by Best Doctors in America 2015-2018

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Neurology

Programs & Centers:

Board Certification:

  • Clinical Neurophysiology, 1997
  • Neurology, 1990

Clinical Expertise:

  • Autoimmune Neuropathy
  • Cognitive Neurology
  • Critical Care Medicine
  • Cryoglobulinemia
  • Dementia
  • Demyelinating Disease
  • Diabetic Neuropathy
  • Dizziness
  • Electromyography (EMG)
  • Electrophysiology (EP) Testing
  • Encephalopathy
  • Epilepsy
  • Facial Nerve Disorders
  • Facial Nerve Rejuvenation
  • Facial Pain
  • Gait Abnormality
  • Guillain-Barré Syndrome (GBS)
  • Headache
  • Herniated Disc Pain
  • Memory Disorders
  • Motor Neuron Diseases (MNDs)
  • Myasthenia Gravis (MG)
  • Nerve Conduction Studies (NCS)
  • Nerve Disease
  • Nerve Injury
  • Neuritis
  • Neuromuscular Disease
  • Neurotoxicity in Cancer Patients
  • Outpatient Electroencephalogram (EEG)
  • Peripheral Nerve Disease
  • Peripheral Neuropathy
  • Post-Polio Syndrome (PPS)
  • Sensory Neuropathy
  • Vertebral Artery Dissection (VAD)

Description of Clinical Expertise

I have more than 20 years experience in diagnosing and treating patients with a variety of neurologic diseases. As a neuromuscular specialist,
I perform electromyography and interpret evoked potentials.

As a treating physician, I focus on the treatment of patients with myasthenia gravis. I am also interested in measuring quality of life in this illness and how it improves with treatment.

My other interests includes treating patients with acquired inflammatory neuropathies, such as cidp, and myopathies such as polymyositis and dermatomyositis.

Most recently, I have developed an interest in amyloid neuropathy and I am collaborating with sister institutions on clinical trials for these diseases.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Penn Presbyterian Medical Center
Fellowship: Hospital of the University of Pennsylvania


International Thymic Malignancy Interest Group, International Philadelphia Neurlogical Society, Local Scientific Advisory Board Myasthenia Gravis Foundation of America, International

Hospital Affiliation

Dr. Khella is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Khella, Sami.: Artist''s statement: Woe. Academic Medicine 85 (9): 1404,2010.

Souayah, Nizar. Khella, Sami L.: A prospective double-blind, placebo-controlled study of thalidomide sensory symptoms in an elderly population with age-related macular degeneration. Journal of Clinical Neuroscience 17 (5): 571-3,2010.

Wolraich, D. Vasile Marchis-Crisan, C. Redding, N. Khella, S L. Mirza, N.: Laryngeal tremor: co-occurrence with other movement disorders. Orl; Journal of Oto-Rhino-Laryngology & its Related Specialties 72 (5): 291-4,2010.

Khella, Sami L.: New insights into stroke in chronic kidney disease. [Review] [73 refs] Advances in Chronic Kidney Disease 15 (4): 338-46,2008.

Khella, Sami. Bleicher, Melissa B.: Stroke and its prevention in chronic kidney disease. [Review] [105 refs] Clinical Journal of The American Society of Nephrology: CJASN 2 (6): 1343-51,2007.

Khella, Sami L. Souyah, Nizar. Dalmau, Josep.: Thymoma, myasthenia gravis, encephalitis, and a novel anticytoplasmic neuronal antibody. Neurology 69 (12): 1302-3,2007.

Prasad, Sashank. El-Haddad, Ghassan. Zhuang, Hongming. Khella, Sami.: Intracranial hypotension following chiropractic spinal manipulation. Headache 46 (9): 1456-8,2006.

Souayah, N. Sander, H W. Menkes, D L. Khella, S L.: Hepatitis C virus acute quadriparetic vasculitic neuropathy responsive to cyclophosphamide. Neurology, Neurophysiology, & Neuroscience : 5,2006.

Souayah, N, Khella, S: Neurology: Examination and Board Review US : 2005.

Homma et al: Warfarin and Aspirin in Patients with Heart Failure and Sinus Rhythm. NEJM : 2012.

Khella SL.: Multiple sclerosis : 2008.

Souyah N, Khella SL: Low dose cyclosporine in myasthenia gravis Souyah N, Khella SL : 2006.

Sagin T, Khella S, Ende J, Morgenstern D: Case #446—Parkinson’s disease. Med Cases online : 2001.

Khella, SL: Electromyography in Shoulder Disorders Orthopaedic Journal : 2000.

Iannotti JP, Hennigan S, Herzog R, Khella S, Kelley M, Leggin B, Williams GR: Latissimus dorsi tendon transfer for irreparable posterosuperior rotator cuff tears. Factors affecting outcome. J Bone Joint Surg Am 88 (2): 2006.

S. Khella, MDϔ; B. Drachman, MDϔ; P. DiVitoϔ; M. Polydefkis, MDϛ; M. Maurerϧ For the TTR Amyloid Consortium, ϔ – University of Pennsylvania, Ϛ –Johns Hopkins University, ϧ – Columbia University: Neurologic Involvement in V 122 Ile Familial Amyloidosis IXth International Symposium on Familial Amyloidotic Polyneuropathy : 2013.

Khella, S. Frederic, M.: Dropped head syndrome. Neurology 43 (4): 846; author reply 846-7,1993.

Huang, J C. Gay, R. Khella, S L.: Sickling crisis, fat embolism, and coma after steroids. Lancet 344 (8927): 951-2,1994.

Khella, S L. Frost, S. Hermann, G A. Leventhal, L. Whyatt, S. Sajid, M A. Scherer, S S.: Hepatitis C infection, cryoglobulinemia, and vasculitic neuropathy. Treatment with interferon alfa: case report and literature review. [Review] [42 refs] Neurology 45 (3 Pt 1): 407-11,1995.

Khella, S L. Kozart, D.: Unmasking and exacerbation of myasthenia gravis by ophthalmic solutions: betoxolol, tobramycin, and dexamethasone. A case report. Muscle & Nerve 20 (5): 631,1997.

Khella, S L.: Neurologic differential diagnosis in podiatry. [Review] [34 refs] Clinics in Podiatric Medicine & Surgery 16 (1): 49-66, vi,1999.

Academic Contact Info

Penn Presbyterian Medical Center
Suite 305 Medical Office Building
3900 Market St

Philadelphia, PA 19104
Phone: (215) 662-8570
Patient appointments: 800-789-7366 (PENN)