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Sameer Khandhar, MD

Sameer Khandhar, MD Physician

Clinical Assistant Professor of Medicine

Languages spoken:

  • Gujarati
  • Hindi

Dr. Khandhar is employed by Penn Medicine.

In New Jersey, providers are affiliated with Penn Medicine through Clinical Health Care Associates of New Jersey.

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About Dr. Sameer Khandhar

Recognized by America's Top Doctors 2015 - 2017

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2009
  • Interventional Cardiology, 2011

Clinical Expertise:

  • Aortic Stenosis
  • Aortic Valve Regurgitation
  • Atherosclerosis (Arteriosclerosis)
  • Atrial Septal Defect (ASD)
  • Cardiac Rehabilitation
  • Cardiogenic Shock
  • Cardiomyopathy
  • Catheter Angiography
  • Chest Pain (Angina)
  • Congestive Heart Failure
  • Coronary Artery Disease
  • Dilated Cardiomyopathy
  • Endocarditis
  • Familial Cardiomyopathy
  • Heart Attack (Myocardial Infarction)
  • Hypertrophic Cardiomyopathy
  • Minimally Invasive Mitral Valve Surgery
  • Mitral Stenosis
  • Mitral Valve Disorders
  • Mitral Valve Regurgitation
  • Myocarditis
  • Pulmonary Valve Stenosis (PVS)
  • Restrictive Cardiomyopathy
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Tricuspid Regurgitation
  • Ultrasound
View More

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Capital Blue Cross
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Northeastern Ohio University - College of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: UPMC Presbyterian


American Association of Physicians of Indian Origin, National American College of Cardiology, National American Heart Association, National American Society of Cardiovascular Angiography and Interventions, National Heart Failure Society of America, National International Society of Heart Lung Transplantation, International

Hospital Affiliation

Dr. Khandhar is employed by Penn Medicine.

Hospital Privileges:

  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Kudaravalli M, Althouse AD, Marroquin OC, Khandhar SJ, Sharbaugh MS, Toma C, Conrad Smith AJ, Schindler JT, Lee JS, Mulukutla SR: Assessment of P2Y12 inhibitor usage and switching in acute coronary syndrome patients undergoing percutaneous coronary revascularization. International Journal of Cardiology 223 : 854-859,2016.

Jones CR, Khandhar SJ, Ramratnam M, Mulukutla SR, Marroquin OC, Althouse AD, Rao A, Kato K, Jang IK, Toma C: Identification of Intrastent Pathology Associated With Late Stent Thrombosis Using Optical Coherence Tomography. Journal of Interventional Cardiology 28 (5): 439-48,2015.

Esper SA, Bermudez C, Dueweke EJ, Kormos R, Subramaniam K, Mulukutla S, Sappington P, Waters J, Khandhar SJ: Extracorporeal membrane oxygenation support in acute coronary syndromes complicated by cardiogenic shock. Catheterization and Cardiovascular Interventions 86 (Suppl 1): S45-50,2015.

Kudaravalli M, Mulukutla S, Delgado J, Comerci JT, Toma C, Marroquin O, Lee JS, Smith C, Sezler F, Brooks MM, Khandhar SJ: Incidence and clinical outcomes of switching P2Y12 inhibitors in ACS patients undergoing PCI. SCAI The Society for Cardiovascular Angiography and Interventions Foundation : 2014 .

Patel M, Cavalcante J, Crock F, Katz W, Schindler JT, Khanna M, Khandhar SJ: Hemodynamic assessment of low-gradient aortic stenosis with preserved ejection fraction. J Am Coll Cardiol 63 (12S): 2014.

Dueweke EJ, Esper SA, Bermudez C, Bhama JK, Puyana S, Subramaniam K, Mulutkutla SR, Waaters J, Marroquin OC, Toma C, Smith C, Khandhar SJ: The use of extracorporeal membrane oxygenation in cardiogenic shock complicated acute coronary syndromes. The Society of Thoracic Surgeons (STS) : 2014.

Patel M, Cavalcante J, Crock F, Katz W, Schindler JT, Khanna M, Khandhar SJ: Hemodynamic assessment of low-gradient aortic stenosis with preserved ejection fraction. American College of Cardiology : 2014.

Jones M, Patel S, Teferra L, Borrebach J, Bermudez C, Bhama J, Kormos R, SHigemura R, D’Cunha J, Mulukutla SR, Marroquin OC, Toma C, Khandhar SJ: The Impact of Coronary Artery Disease on Lung Transplantation Outcomes. International Society for Heart & Lung Transplantation (ISHLT) : 2014.

Khandhar SJ, Shullo MA, Zeevi A, Toma C, Teuteberg JJ: Relationship Between Anti-HLA Antibodies and Coronary Allograft Vasculopathy after Heart Transplantation. The Journal of Heart and Lung Transplantation 33 (4): S178–S179,2014.

Kudaravalli M, Khandhar S, Delgado J, Comerci JT, Toma C, Marroquin O, Lee JS, Smith C, Sezler F, Brooks MM, Mulukutla S: Prevalence and clinical outcomes of ticagrelor and prasugrel vs clopidogrel in Clinical Practice. The Society for Cardiovascular Angiography and Interventions Foundation : 2014.

Academic Contact Info

Penn Presbyterian Medical Center
51 N 39th St

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)