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Saman Nazarian, MD, PHD

Saman Nazarian, MD, PHD Physician

Associate Professor of Medicine at the Hospital of the University of Pennsylvania

Languages spoken:

  • Persian

Dr. Nazarian is employed by Penn Medicine.

About Dr. Saman Nazarian

Recognized by America's Top Doctors for 2017

Recognized in Philadelphia magazine's May 2018 Top Docs issue

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2006
  • Clinical Cardiac Electrophysiology, 2008

Clinical Expertise:

  • Ablation of Idiopathic Ventricular Tachycardia
  • Advanced Cardiac EP Imaging
  • Arrhythmia
  • Atrial Fibrillation (Afib)
  • Atrial Fibrillation Ablation
  • Biventricular Device Implantation
  • Biventricular Device Optimization
  • Bradycardia
  • Cardiac Catheter Ablation
  • Cardiac Electrophysiology Study (EPS)
  • Cardiac Resynchronization Therapy (CRT)
  • Complex Arrhythmia
  • Electrocardiography (ECG or EKG)
  • Electrophysiology (EP) Testing
  • Epicardial Ablation
  • Heart Block
  • Heart Palpitations
  • Heart Rhythms - Slow/Fast
  • Implantable Cardiac Devices
  • Implantable Cardioverter Defibrillator
  • Inherited Arrhythmia Diseases
  • Pacemaker
  • Radiofrequency Ablation (RFA)
  • Risk Stratification
  • Sick Sinus Syndrome
  • Sinus Node Dysfunction (SND)
  • Supraventricular Tachycardia (SVT)
  • Ventricular Tachycardia
  • Ventricular Tachycardia Ablation
  • Ventricular Tachycardia Procedures
  • Wolff-Parkinson-White Syndrome

Description of Clinical Expertise

Dr. Nazarian is an Associate Professor in the Cardiac Electrophysiology section of the Department of Medicine at the University of Pennsylvania Perelman School of Medicine. Dr. Nazarian earned his M.D. degree from the Stanford University School of Medicine. He completed his internship and residency training in Internal Medicine at the Brigham and Women’s Hospital of Harvard Medical School. He then completed serial fellowships in Cardiovascular Medicine and Clinical Cardiac Electrophysiology at the Johns Hopkins University School of Medicine. Following completion of his training he joined the Electrophysiology Faculty at the Johns Hopkins Hospital. At Johns Hopkins he developed a busy clinical practice as well as an active portfolio of National Institutes of Health funded research. He was promoted to Associate Professor of Medicine and Director of the Ventricular Arrhythmia Ablation service by 2014. In 2016, Dr. Nazarian joined the Electrophysiology Faculty at the Hospital of the University of Pennsylvania where he will continue to focus on his clinical interests including:

• Atrial and ventricular arrhythmia substrate identification and ablation
• Optimal catheter ablation strategies for longstanding persistent atrial fibrillation
• Prevention of sudden cardiac death
• Implantation and management of permanent pacemakers, defibrillators, and cardiac resynchronization systems
• Arrhythmia risk management in patients with neurologic disease
• Management of arrhythmias in cardiac sarcoidosis
• Management of arrhythmias in hypertrophic cardiomyopathy

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Stanford University School of Medicine
Residency: Brigham and Women's Hospital
Fellowship: Johns Hopkins Hospital


American College of Cardiology, National American College of Cardiology, National American College of Radiology, National American Heart Association, National American Heart Association, National American Medical Association, National Heart Rhythm Society, National Heart Rhythm Society, National Stanford Medical Alumni Association, Local

Hospital Affiliation

Dr. Nazarian is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Nazarian is an active investigator in the field of cardiac electrophysiology and is particularly interested in integration of advanced imaging modalities for optimization of procedural success for ablation of complex ventricular arrhythmia in structural heart disease. In addition to his medical expertise, Dr. Nazarian has a Ph.D. degree in Clinical Epidemiology from the Johns Hopkins Bloomberg School of Public Health. He has published extensively on the anatomy of the ventricular arrhythmia substrate. In his arrhythmia imaging laboratory, he oversees a team of individuals dedicated to facilitating atrial and ventricular arrhythmia research and clinical care within an academic medical center environment. In 2013, he was awarded a $1 million grant from the National Institutes of Health to characterize the substrate for malignant arrhythmia.

Selected Publications:

Markman Timothy M, Ruble Kathryn, Loeb David, Chen Allen, Zhang Yiyi, Beasley Gary S, Thompson W Reid, Nazarian Saman: Electrophysiological effects of anthracyclines in adult survivors of pediatric malignancy. Pediatric blood & cancer 64 (11): 2017.

Enriquez Andres, Pathak Rajeev K, Santangeli Pasquale, Liang Jackson J, Al Rawahi Mohammed, Hayashi Tatsuya, Muser Daniele, Frankel David S, Supple Gregory, Schaller Robert, Lin David, Nazarian Saman, Zado Erica, Marchlinski Francis E, Garcia Fermin C: Inferior lead discordance in ventricular arrhythmias: A specific marker for certain arrhythmia locations. Journal of cardiovascular electrophysiology 28 (10): 1179-1186,2017.

Nazarian Saman, Zghaib Tarek: Is Atrial Fibrillation a Necessary Component of the Thrombogenic Atrium? Journal of the American College of Cardiology 70 (11): 1322-1324,2017.

O'Neal Wesley T, Nazarian Saman, Alonso Alvaro, Heckbert Susan R, Vaccarino Viola, Soliman Elsayed Z: Sex hormones and the risk of atrial fibrillation: The Multi-Ethnic Study of Atherosclerosis (MESA). Endocrine : 2017.

Indik Julia H, Gimbel J Rod, Abe Haruhiko, Alkmim-Teixeira Ricardo, Birgersdotter-Green Ulrika, Clarke Geoffrey D, Dickfeld Timm-Michael L, Froelich Jerry W, Grant Jonathan, Hayes David L, Heidbuchel Hein, Idriss Salim F, Kanal Emanuel, Lampert Rachel, Machado Christian E, Mandrola John M, Nazarian Saman, Patton Kristen K, Rozner Marc A, Russo Robert J, Shen Win-Kuang, Shinbane Jerold S, Teo Wee Siong, Uribe William, Verma Atul, Wilkoff Bruce L, Woodard Pamela K: 2017 HRS expert consensus statement on magnetic resonance imaging and radiation exposure in patients with cardiovascular implantable electronic devices. Heart rhythm 14 (7): e97-e153,2017.

Gleason Kelly T, Nazarian Saman, Dennison Himmelfarb Cheryl R: Atrial Fibrillation Symptoms and Sex, Race, and Psychological Distress: A Literature Review. The Journal of cardiovascular nursing : 2017.

Balouch Muhammad, Gucuk Ipek Esra, Chrispin Jonathan, Bajwa Rizma J, Zghaib Tarek, Berger Ronald D, Ashikaga Hiroshi, Nazarian Saman, Marine Joseph E, Calkins Hugh, Spragg David D: Impact of rotor temperospatial stability on acute and one-year atrial fibrillation ablation outcomes. Clinical cardiology 40 (6): 383-389,2017.

Markman Timothy M, Nazarian Saman: Risk Stratification for Sudden Cardiac Death: Is It Too Late to Establish a Role for Cardiac MRI? Circulation 135 (22): 2116-2118,2017.

Markman Timothy M, Nazarian Saman: Anticoagulation for atrial fibrillation in dialysis patients: What is known and what does the future hold? Heart rhythm 14 (5): 652-653,2017.

O'Neal Wesley T, Efird Jimmy T, Nazarian Saman, Alonso Alvaro, Michos Erin D, Szklo Moses, Heckbert Susan R, Soliman Elsayed Z: Mitral annular calcification progression and the risk of atrial fibrillation: results from MESA. European heart journal cardiovascular Imaging : 2017.

View all publications

Academic Contact Info

Hospital of the University of Pennsylvania
Cardiac Electrophysiology, 9 Founders Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 615-5220
Patient appointments: 800-789-7366 (PENN)