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Saman Nazarian, MD, PHD

Saman Nazarian, MD, PHD Physician

Associate Professor of Medicine at the Hospital of the University of Pennsylvania

Languages spoken:

  • Persian

Dr. Nazarian is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2006
  • Clinical Cardiac Electrophysiology, 2008

Clinical Expertise:

  • Ablation of Idiopathic Ventricular Tachycardia
  • Ablation of Ventricular Tachycardia
  • Advanced Cardiac EP Imaging
  • Arrhythmia
  • Atrial Fibrillation (Afib)
  • Atrial Fibrillation Ablation
  • Biventricular Device Implantation
  • Biventricular Device Optimization
  • Bradycardia
  • Cardiac Catheter Ablation
  • Cardiac Electrophysiology Study (EPS)
  • Cardiac Resynchronization Therapy (CRT)
  • Complex Arrhythmia
  • Electrocardiography (ECG or EKG)
  • Electrophysiology (EP) Testing
  • Epicardial Ablation
  • Heart Block
  • Heart Palpitations
  • Heart Rhythms - Slow/Fast
  • Implantable Cardiac Devices
  • Implantable Cardioverter Defibrillator
  • Inherited Arrhythmia Diseases
  • Pacemaker
  • Radiofrequency Ablation (RFA)
  • Risk Stratification
  • Sick Sinus Syndrome
  • Sinus Node Dysfunction (SND)
  • Supraventricular Tachycardia (SVT)
  • Ventricular Tachycardia
  • Ventricular Tachycardia Procedures
  • Wolff-Parkinson-White Syndrome

Description of Clinical Expertise

Dr. Nazarian is an Associate Professor in the Cardiac Electrophysiology section of the Department of Medicine at the University of Pennsylvania Perelman School of Medicine. Dr. Nazarian earned his M.D. degree from the Stanford University School of Medicine. He completed his internship and residency training in Internal Medicine at the Brigham and Women’s Hospital of Harvard Medical School. He then completed serial fellowships in Cardiovascular Medicine and Clinical Cardiac Electrophysiology at the Johns Hopkins University School of Medicine. Following completion of his training he joined the Electrophysiology Faculty at the Johns Hopkins Hospital. At Johns Hopkins he developed a busy clinical practice as well as an active portfolio of National Institutes of Health funded research. He was promoted to Associate Professor of Medicine and Director of the Ventricular Arrhythmia Ablation service by 2014. In 2016, Dr. Nazarian joined the Electrophysiology Faculty at the Hospital of the University of Pennsylvania where he will continue to focus on his clinical interests including:

• Atrial and ventricular arrhythmia substrate identification and ablation
• Optimal catheter ablation strategies for longstanding persistent atrial fibrillation
• Prevention of sudden cardiac death
• Implantation and management of permanent pacemakers, defibrillators, and cardiac resynchronization systems
• Arrhythmia risk management in patients with neurologic disease
• Management of arrhythmias in cardiac sarcoidosis
• Management of arrhythmias in hypertrophic cardiomyopathy

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Stanford University School of Medicine
Residency: Brigham and Women's Hospital
Fellowship: Johns Hopkins Hospital


American College of Cardiology, National American College of Cardiology, National American College of Radiology, National American Heart Association , National American Heart Association , National American Medical Association , National Heart Rhythm Society, National Heart Rhythm Society, National Stanford Medical Alumni Association, Local

Hospital Affiliation

Dr. Nazarian is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Nazarian is an active investigator in the field of cardiac electrophysiology and is particularly interested in integration of advanced imaging modalities for optimization of procedural success for ablation of complex ventricular arrhythmia in structural heart disease. In addition to his medical expertise, Dr. Nazarian has a Ph.D. degree in Clinical Epidemiology from the Johns Hopkins Bloomberg School of Public Health. He has published extensively on the anatomy of the ventricular arrhythmia substrate. In his arrhythmia imaging laboratory, he oversees a team of individuals dedicated to facilitating atrial and ventricular arrhythmia research and clinical care within an academic medical center environment. In 2013, he was awarded a $1 million grant from the National Institutes of Health to characterize the substrate for malignant arrhythmia.

Selected Publications:

Tao Q, Ipek EG, Shahzad R, Berendsen FF, Nazarian S, van der Geest RJ: Fully automatic segmentation of left atrium and pulmonary veins in late gadolinium-enhanced MRI: Towards objective atrial scar assessment. Journal of Magnetic Resonance Imaging 44 (2): 346-54,2016.

Habibi M, Lima JA, Gucuk Ipek E, Zimmerman SL, Zipunnikov V, Spragg D, Ashikaga H, Rickard J, Marine JE, Berger RD, Calkins H, Nazarian S : The association of baseline left atrial structure and function measured with cardiac magnetic resonance and pulmonary vein isolation outcome in patients with drug-refractory atrial fibrillation. Heart Rhythm 13 (5): 1037-44,2016.

Suzuki T, Nazarian S, Jerosch-Herold M, Chugh SS.: Imaging for assessment of sudden death risk: current role and future prospects. Europace : 2016.

Zahid S, Whyte KN, Schwarz EL, Blake RC 3rd, Boyle PM, Chrispin J, Prakosa A, Ipek EG, Pashakhanloo F, Halperin HA, Calkins H, Berger RD, Nazarian S, Trayanova NA: Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter. Heart Rhythm (16): S1547-5271,2016.

Chrispin J, Ipek EG, Habibi M, Yang E, Spragg D, Marine JE, Ashikaga H, Rickard J, Berger RD, Zimmerman SL, Calkins H, Nazarian S: Clinical predictors of cardiac magnetic resonance late gadolinium enhancement in patients with atrial fibrillation. Europace : 2016.

Chrispin J, Gucuk Ipek E, Zahid S, Prakosa A, Habibi M, Spragg D, Marine JE, Ashikaga H, Rickard J, Trayanova NA, Zimmerman SL, Zipunnikov V, Berger RD, Calkins H, Nazarian S: Lack of regional association between atrial late gadolinium enhancement on cardiac magnetic resonance and atrial fibrillation rotors. Heart Rhythm 13 (3): 654-60,2016.

Fukumoto K, Habibi M, Ipek EG, Zahid S, Khurram IM, Zimmerman SL, Zipunnikov V, Spragg D, Ashikaga H, Trayanova N, Tomaselli GF1, Rickard J, Marine JE, Berger RD, Calkins H, Nazarian S: Association of Left Atrial Local Conduction Velocity With Late Gadolinium Enhancement on Cardiac Magnetic Resonance in Patients With Atrial Fibrillation. Circulation Arrhythmia and electrophysiology 9 (3): e002897,2016.

Khurram IM, Maqbool F, Berger RD, Marine JE, Spragg DD, Ashikaga H, Zipunnikov V, Kass DA, Calkins H, Nazarian S, Zimmerman SL: Association Between Left Atrial Stiffness Index and Atrial Fibrillation Recurrence in Patients Undergoing Left Atrial Ablation. Circulation Arrhythmia and Electrophysiology 9 (3): 2016.

Tanawuttiwat T, Nazarian S, Calkins H: The role of catheter ablation in the management of ventricular tachycardia. European Heart Journal 37 (7): 594-609,2016.

Gucuk Ipek E, Marine JE, Habibi M, Chrispin J, Lima J, Rickard J, Spragg D, Zimmerman SL, Zipunnikov V, Berger R, Calkins H, Nazarian S: Association of left atrial function with incident atypical atrial flutter after atrial fibrillation ablation. Heart Rhythm 13 (2): 391-8,2016.

View all publications

Academic Contact Info

Hospital of the University of Pennsylvania
Cardiac Electrophysiology, 9 Founders Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Phone: 215-615-5220
Fax: 215-615-5235
Patient appointments: 800-789-7366 (PENN)