Description of Research Expertise:
Tumor Immunology
Chimeric Antigen Receptor T cells
Mouse Models of Human Leukemia
Murine Xenografts
Adoptive Cellular Therapy
Genetic Engineering of T cells
Flow Cytometry
Selected Publications:
Saar Gill: How close are we to CAR T-cell therapy for AML? Best Pract Res Clin Haematol : 2019.
Duell Johannes, Lammers Philip E, Djuretic Ivana, Chunyk Allison G, Alekar Shilpa, Jacobs Ira, Gill Saar: Bispecific Antibodies in the Treatment of Hematologic Malignancies. Clinical pharmacology and therapeutics 106 (4): 781-791,2019.
Cummins Katherine D, Gill Saar: Chimeric antigen receptor T-cell therapy for acute myeloid leukemia: how close to reality? Haematologica 104 (7): 1302-1308,2019.
Kansagra Ankit J, Frey Noelle V, Bar Merav, Laetsch Theodore W, Carpenter Paul A, Savani Bipin N, Heslop Helen E, Bollard Catherine M, Komanduri Krishna V, Gastineau Dennis A, Chabannon Christian, Perales Miguel A, Hudecek Michael, Aljurf Mahmoud, Andritsos Leslie, Barrett John A, Bachanova Veronika, Bonini Chiara, Ghobadi Armin, Gill Saar I, Hill Joshua A, Kenderian Saad, Kebriaei Partow, Nagler Arnon, Maloney David, Liu Hien D, Shah Nirali N, Kharfan-Dabaja Mohamed A, Shpall Elizabeth J, Mufti Ghulam J, Johnston Laura, Jacoby Elad, Bazarbachi Ali, DiPersio John F, Pavletic Steven Z, Porter David L, Grupp Stephan A, Sadelain Michel, Litzow Mark R, Mohty Mohamad, Hashmi Shahrukh K: Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT). Bone marrow transplantation : 2019.
Ganetsky Alex, Han Jennifer H, Hughes Mitchell E, Babushok Daria V, Frey Noelle V, Gill Saar I, Hexner Elizabeth O, Loren Alison W, Luger Selina M, Mangan James K, Martin Mary Ellen, Smith Jacqueline, Freyer Craig W, Gilmar Cheryl, Schuster Mindy, Stadtmauer Edward A, Porter David L: Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 68 (12): 2003-2009,2019.
Cummins Katherine D, Gill Saar: Will CAR T cell therapy have a role in AML? Promises and pitfalls. Seminars in hematology 56 (2): 155-163,2019.
Petty Nicholas E, Gill Saar I: 21 Century FOX: Toward Gene Therapy for the Regulatory T Cell Deficiency Syndrome IPEX. Cell stem cell 24 (2): 208-209,2019.
Kansagra Ankit J, Frey Noelle V, Bar Merav, Laetsch Theodore W, Carpenter Paul A, Savani Bipin N, Heslop Helen E, Bollard Catherine M, Komanduri Krishna V, Gastineau Dennis A, Chabannon Christian, Perales Miguel A, Hudecek Michael, Aljurf Mahmoud, Andritsos Leslie, Barrett John A, Bachanova Veronika, Bonini Chiara, Ghobadi Armin, Gill Saar I, Hill Joshua, Kenderian Saad, Kebriaei Partow, Nagler Arnon, Maloney David, Liu Hien D, Shah Nirali N, Kharfan-Dabaja Mohamed A, Shpall Elizabeth J, Mufti Ghulam J, Johnston Laura, Jacoby Elad, Bazarbachi Ali, DiPersio John F, Pavletic Steven Z, Porter David L, Grupp Stephan A, Sadelain Michel, Litzow Mark R, Mohty Mohamad, Hashmi Shahrukh K: Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 25 (3): e76-e85,2019.
Ruella M, Barrett DM, Shestova O, Perazzelli J, Posey AD, Hong SJ, Kozlowski M, Lacey SF, Melenhorst JJ, June CH, Gill S: A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor positive cells Blood : 2019.
Frey NV, Shaw PA, Hexner EO, Pequignot E, Gill S, Luger SM, Mangan JK, Loren AW, Perl AE, Maude SL, Grupp SA, Shah NN, Gilmore J, Lacey SF, Melenhorst JJ, Levine BL, June CH, Porter DL: Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia Journal of Clinical Oncology : 2019.