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Saar I. Gill, MD

Saar I. Gill, MD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Gill is a Penn Medicine employed physician.

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Clinical Specialties


  • Hematology
  • Medical Oncology

Programs & Centers:

Board Certification:

  • Physicians

Clinical Expertise:

  • Bone Marrow Transplant
  • Leukemia
  • Myelodysplastic Syndromes (MDS)
  • Stem Cell Transplant

Description of Clinical Expertise

Blood and Marrow Transplantation
Myelodysplastic Syndromes
Myeloproliferative Neoplasms
Lymphoproliferative Neoplasms
Bone Marrow Failure

Practice Locations and Appointments

  • Abramson Cancer Center

    Perelman Center for Advanced Medicine West Pavilion, 2nd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Melbourne
Residency: St. Vincent's Hospital Melbourne
Residency: St. Vincent Hospital
Residency: St. Vincent's Hospital
Fellowship: Peter MacCallum Cancer Centre
Fellowship: Hospital of the University of Pennsylvania


American Society of Blood and Marrow Transplantation, International American Society of Hematology, International Haematology Society of Australia and New Zealand, National

Hospital Affiliation

Dr. Gill is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Tumor Immunology
Chimeric Antigen Receptor T cells
Mouse Models of Human Leukemia
Murine Xenografts
Adoptive Cellular Therapy
Genetic Engineering of T cells
Flow Cytometry

Selected Publications:

Ruella Marco, Barrett David M, Kenderian Saad S, Shestova Olga, Hofmann Ted J, Perazzelli Jessica, Klichinsky Michael, Aikawa Vania, Nazimuddin Farzana, Kozlowski Miroslaw, Scholler John, Lacey Simon F, Melenhorst Jan J, Morrissette Jennifer J D, Christian David A, Hunter Christopher A, Kalos Michael, Porter David L, June Carl H, Grupp Stephan A, Gill Saar: Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. The Journal of clinical investigation 126 (10): 3814-3826,2016.

Kenderian Saad S, Porter David L, Gill Saar: Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation : 2016.

Gill Saar: Planes, Trains, and Automobiles: Perspectives on CAR T Cells and Other Cellular Therapies for Hematologic Malignancies. Current hematologic malignancy reports 11 (4): 318-25,2016.

Kumar Anita J, Vassilev Pavel, Loren Alison W, Luger Selina M, Reshef Ran, Gill Saar, Smith Jacqueline, Goldstein Steven C, Hexner Elizabeth, Stadtmauer Edward A, Porter David, Frey Noelle V: Time to unrelated donor leukocyte infusion is longer, but incidence of GVHD and overall survival are similar for recipients of unrelated DLI compared to matched sibling DLI. American journal of hematology 91 (4): 426-9,2016.

Ruella Marco, Kenderian Saad S, Shestova Olga, Fraietta Joseph A, Qayyum Sohail, Zhang Qian, Maus Marcela V, Liu Xiaobin, Nunez-Cruz Selene, Klichinsky Michael, Kawalekar Omkar U, Milone Michael, Lacey Simon F, Mato Anthony, Schuster Stephen J, Kalos Michael, June Carl H, Gill Saar, Wasik Mariusz A: The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research 22 (11): 2684-96,2016.

Fraietta Joseph A, Beckwith Kyle A, Patel Prachi R, Ruella Marco, Zheng Zhaohui, Barrett David M, Lacey Simon F, Melenhorst Jan Joseph, McGettigan Shannon E, Cook Danielle R, Zhang Changfeng, Xu Jun, Do Priscilla, Hulitt Jessica, Kudchodkar Sagar B, Cogdill Alexandria P, Gill Saar, Porter David L, Woyach Jennifer A, Long Meixiao, Johnson Amy J, Maddocks Kami, Muthusamy Natarajan, Levine Bruce L, June Carl H, Byrd John C, Maus Marcela V: Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia. Blood 127 (9): 1117-27,2016.

Saar Gill: Rationale, mechanism of action and clinical results of bispecific antibodies in oncology: blinatumomab and beyond. Medscape : 2016.

Sotillo Elena, Barrett David M, Black Kathryn L, Bagashev Asen, Oldridge Derek, Wu Glendon, Sussman Robyn, Lanauze Claudia, Ruella Marco, Gazzara Matthew R, Martinez Nicole M, Harrington Colleen T, Chung Elaine Y, Perazzelli Jessica, Hofmann Ted J, Maude Shannon L, Raman Pichai, Barrera Alejandro, Gill Saar, Lacey Simon F, Melenhorst Jan J, Allman David, Jacoby Elad, Fry Terry, Mackall Crystal, Barash Yoseph, Lynch Kristen W, Maris John M, Grupp Stephan A, Thomas-Tikhonenko Andrei: Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy. Cancer discovery 5 (12): 1282-95,2015.

Gill Saar, Maus Marcela V, Porter David L: Chimeric antigen receptor T cell therapy: 25years in the making. Blood reviews 30 (3): 157-67,2015.

Reshef Ran, Huffman Austin P, Gao Amy, Luskin Marlise R, Frey Noelle V, Gill Saar I, Hexner Elizabeth O, Kambayashi Taku, Loren Alison W, Luger Selina M, Mangan James K, Nasta Sunita D, Richman Lee P, Sell Mary, Stadtmauer Edward A, Vonderheide Robert H, Mick Rosemarie, Porter David L: High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33 (21): 2392-8,2015.

Academic Contact Info

Room 8-101
Smilow Translational Research Center
3400 Civic Center Blvd

Philadelphia, PA 19104
Phone: (215) 573-4015
Patient appointments: 800-789-7366 (PENN)