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Saar I. Gill, MD, PhD

Saar I. Gill, MD, PhD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Gill is employed by Penn Medicine.

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Clinical Specialties

Clinical Expertise:

  • Bone Marrow Transplant
  • Leukemia
  • Myelodysplastic Syndromes (MDS)
  • Stem Cell Transplant

Description of Clinical Expertise

Blood and Marrow Transplantation
Myelodysplastic Syndromes
Myeloproliferative Neoplasms
Lymphoproliferative Neoplasms
Bone Marrow Failure

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Melbourne
Residency: St. Vincent's Hospital Melbourne
Residency: St. Vincent Hospital
Residency: St. Vincent's Hospital
Fellowship: Peter MacCallum Cancer Centre
Fellowship: Hospital of the University of Pennsylvania


American Society of Blood and Marrow Transplantation, International American Society of Gene & Cell Therapy, International American Society of Hematology, International Immunology and Host Defense Committee of the American Society of Hematology, National

Hospital Affiliation

Dr. Gill is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Tumor Immunology
Chimeric Antigen Receptor T cells
Mouse Models of Human Leukemia
Murine Xenografts
Adoptive Cellular Therapy
Genetic Engineering of T cells
Flow Cytometry

Selected Publications:

Cummins KD*, Frey N*, Nelson AM*, Schmidt A*, Luger S, Isaacs RE*, Lacey SF, Hexner E, Melenhorst JJ, June CH, Porter DL, Gill SI.: Treating Relapsed / Refractory (RR) AML with Biodegradable AntiCD123 CAR Modified T Cells American Society for Hematology Annual Meeting, Atlanta, GA : 2017.

Ruella M*, Maude SL*, Engels B*, Barrett DM*, Frey N*, Marcucci K, Shestova O, Singh N, Perazzelli J, Christian DA, Hunter CA, Haagen D, Lacey S, Melenhorst J, Brogdon J, Young R, Porter DL, June CH, Grupp S, Gill S.: Clinical efficacy of anti-CD22 chimeric antigen receptor T cells for B-cell acute lymphoblastic leukemia is correlated with the length of the scFv linker and can be predicted using xenograft models American Society for Hematology Annual Meeting, Atlanta, GA : 2017.

Ruella M, Xu J, Barrett DM*, Kulikovskaya I*, Ambrose DE*, Patel PR*, Reich T*, Scholler J*, Nazimuddin F*, Fraietta JA*, Maude SL, Gill SI, Levine BL, Nobles CL*, Bushman FD*, Orlando E*, Grupp SA, June CH, Melenhorst JJ, Lacey SF.: Iatrogenic Induction of Chimeric Antigen Receptor Therapy Resistance American Society of Hematology Annual Meeting, Atlanta, GA : 2017.

Ruella M, Klichinsky M, Kenderian SS, Shestova O, Ziober A, Kraft DO, Feldman M, Wasik MA, June CH, Gill S: Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells Cancer Discovery 7 (10): 1154-67,2017.

Gill SI*, Frey NV, Hexner EO, Lacey SF, Melenhorst JJ, Hwang W, June CH, Porter DL.: Combination of humanized CD19-targeted chimeric antigen receptor T cells with ibrutinib in adults with chronic lymphocytic leukemia American Society of Clinical Oncology Annual Meeting, Chicago, IL : 2017.

Tasian Sarah K, Kenderian Saad S, Shen Feng, Ruella Marco, Shestova Olga, Kozlowski Miroslaw, Li Yong, Schrank-Hacker April, Morrissette Jennifer J D, Carroll Martin, June Carl H, Grupp Stephan A, Gill Saar: Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia. Blood 129 (17): 2395-2407,2017.

Glisovic-Aplenc Tina, Gill Saar, Spruce Lynn A, Smith Ian R, Fazelinia Hossein, Shestova Olga, Ding Hua, Tasian Sarah K, Aplenc Richard, Seeholzer Steven H: Improved surfaceome coverage with a label-free nonaffinity-purified workflow. Proteomics 17 (7): 2017.

Gill Saar: Monkey business: Repurposing a protein from the simian immunodeficiency virus to enhance cytotoxic chemotherapy. Science translational medicine 9 (375): 2017.

Kenderian Saad S, Porter David L, Gill Saar: Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 23 (2): 235-246,2017.

Gill Saar: CAR T cells engage in anticancer martial arts. Science translational medicine 9 (373): 2017.

Academic Contact Info

Room 8-101
Smilow Translational Research Center
3400 Civic Center Blvd

Philadelphia, PA 19104
Phone: (215) 573-4015
Patient appointments: 800-789-7366 (PENN)