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Ronald L. Wolf, MD, PhD

Ronald L. Wolf, MD, PhD Physician

Chief, MRI Modality Associate Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Wolf is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Neuroradiology, 2000
  • Radiology, 1998

Clinical Expertise:

  • Angiography
  • Angioplasty
  • Arterial Dissection
  • Biopsy
  • Cryoablation
  • CT Scan (Computed Tomography)
  • CT Scan Guided Biopsy
  • CTA (Computed Tomography Angiography)
  • Diagnostic Imaging
  • Diagnostic Test
  • Embolization
  • Microwave Ablation (MWA)
  • Minimally Invasive Surgery
  • MRA (Magnetic Resonance Angiography)
  • MRI (Magnetic Resonance Imaging)
  • Nuclear Imaging
  • Radiofrequency Ablation (RFA)
  • Stent Placement
  • Steroid Injection
  • Ultrasound
  • X-Ray
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program
  • Vibra Health Plan

Education and Training

Medical School: Mayo Medical School
Residency: Johns Hopkins Hospital
Fellowship: Hospital of the University of Pennsylvania


American Society of Functional Neuroradiology (ASFNR), National American Society of Neuroradiology (ASNR), National International Society of Magnetic Resonance in Medicine (ISMRM), International Radiological Society of North America (RSNA), International The Eastern Neuroradiological Society (ENRS), Local

Hospital Affiliation

Dr. Wolf is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

I am primarily interested in the imaging of acute and chronic cerebrovascular disease. The immediate goal of current projects is to gain a better understanding of carotid atherosclerosis and its relationship to stroke using structural MR and CT techniques. The long-term goal is to integrate structural imaging of the brain and extracranial and intracranial blood vessels with functional imaging methods of the brain, including perfusion-weighted imaging (PWI), diffusion-weighted and diffusion tensor imaging (DWI and DTI), functional MRI (fMRI), and/or spectroscopy in order to generate a comprehensive exam for the evaluation of cerebrovascular disease. I have a particular interest in perfusion imaging of the brain using a variety of techniques, including bolus contrast CT and MR perfusion, stable xenon CT perfusion, and arterial spin labeled (ASL) perfusion imaging. This interest targets not only cerebrovascular disease but also nonischemic pathology, especially CNS neoplasms and associated treatment effects.

Selected Publications:

Wolf RL (Guest Editor): Essentials of Neuroradiology Radiol Clin North Am 44 (1): 2006.

Jones CE, Wolf RL, Detre JA, Das B, Saha PK, Wang J, Zhang Y, Song HK, Wright AC, Mohler, EM, III, Fairman RM, Zager EL, Velazquez OC, Golden MA, Carpenter JP, Wehrli FW: Characterization of hemispheric cerebral blood flow before and after carotid endarterectomy using unilateral arterial spin labeling. NMR Biomed 19 : 198-208,2006.

Wang S, Wolf RL, Woo JH, Wang J, O’Rourke DM, Roy S, Melhem ER, Poptani H: Actinomycotic Brain Infection: Registered Diffusion, Perfusion MR Imaging and MR Spectroscopy Neuroradiology 48 (5): 346-350,2006.

Wolf RL, Wang J, Wang S, Melhem ER, O’Rourke DM, Judy KD, Detre JA.: Grading of CNS Neoplasms Using Continuous Arterial Spin Labeled Perfusion MR Imaging at 3 Tesla J Magn Reson Imaging 22 : 475-482,2005.

Wolf RL, Wehrli SL, Popescu AM, Woo JH, Song HK, Wright AC, Mohler EM, III, Harding JD, Zager EL, Fairman RM, Golden MA, Velazquez OC, Carpenter JP, Wehrli FW.: Mineral volume and morphology in carotid plaque specimens using high resolution magnetic resonance imaging and computed tomography Arterioscler Thromb Vasc Biol 25 : 1729-1735,2005.

Wang J, Zhang Y, Wolf RL, Roc AC, Alsop DC, Detre JA.: Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study Radiology 235 : 218-228,2005.

Kasner SE, Sheth KN, Wu GF, Messe SR, Wolf RL: Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients Neurology 65 : 337-338,2005.

Wolf RL: Invited commentary for Nunez DB, Jr, Torres-Leon MT, Munera F. Vascular injuries of the neck and thoracic inlet: helical CT-angiographic correlation. Radiographics 2004;24:1087-1100 Radiographics 24 (4): 1099-1100,2004.

Sheth KN, Wu G, Messe SR, Wolf RL, Kasner SE: Dialysis disequilibrium: another reversible posterior leukoencephalopathy syndrome? Clinical Neurology and Neurosurgery 105 : 249-252,2003.

Academic Contact Info

University of Pennsylvania Medical Center
Department of Radiology
Section of Neuroradiology, 219 Dulles
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 349-5184
Patient appointments: 800-789-7366 (PENN)

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