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Ronald L. Wolf, MD, PhD

Ronald L. Wolf, MD, PhD Physician

Chief, MRI Modality
Associate Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Wolf is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Radiology

Programs & Centers:

Board Certification:

  • Neuroradiology, 2000
  • Radiology, 1998

Description of Clinical Expertise

As an academic neuroradiologist, my clinical skills are applied primarily to noninvasive imaging studies of brain, head and neck, and spine. While I do perform interventional studies such as conventional angiography, myelography/cisternography, and image-guided lumbar or cervical punctures, my participation is almost always in the role of diagnostician. Areas of particular clinical interest parallel research interests; specifically, I am interested in neuroimaging of cerebrovascular disease and CNS neoplasia. In this light, I have expertise in many standard neuroimaging modalities (e.g., CT and MRI) as well as advanced imaging techniques, including noninvasive angiography, perfusion imaging, diffusion imaging, fMRI, and spectroscopy.

Practice Locations and Appointments

  • Penn Radiology

    Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

  • Penn Radiology

    Penn Medicine Bucks County 777 Township Line Road Yardley, PA 19067 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

  • Penn Radiology

    Penn Presbyterian Medical Center Cupp Pavilion 51 N. 39th Street Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of Penn Presbyterian Medical Center

  • Penn Radiology

    Pennsylvania Hospital 800 Spruce Street Philadelphia, PA 19107 800-789-PENN (7366)

    A facility of Pennsylvania Hospital

  • Penn Radiology

    Perelman Center for Advanced Medicine Atrium, Ground Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

  • Penn Radiology

    Penn Medicine Radnor 250 King of Prussia Road Radnor, PA 19087 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

  • Penn Radiology

    Penn Medicine University City 7th Floor 3737 Market Street Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of Penn Presbyterian Medical Center

  • Penn Radiology

    Penn Medicine Valley Forge 1001 Chesterbrook Boulevard Berwyn, PA 19312 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Mayo Medical School
Residency: Johns Hopkins Hospital
Fellowship: Hospital of the University of Pennsylvania

Memberships

American Society of Functional Neuroradiology (ASFNR), National American Society of Neuroradiology (ASNR), National International Society of Magnetic Resonance in Medicine (ISMRM), International Radiological Society of North America (RSNA), International

Hospital Affiliation

Dr. Wolf is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

I am primarily interested in the imaging of acute and chronic cerebrovascular disease. The immediate goal of current projects is to gain a better understanding of carotid atherosclerosis and its relationship to stroke using structural MR and CT techniques. The long-term goal is to integrate structural imaging of the brain and extracranial and intracranial blood vessels with functional imaging methods of the brain, including perfusion-weighted imaging (PWI), diffusion-weighted and diffusion tensor imaging (DWI and DTI), functional MRI (fMRI), and/or spectroscopy in order to generate a comprehensive exam for the evaluation of cerebrovascular disease. I have a particular interest in perfusion imaging of the brain using a variety of techniques, including bolus contrast CT and MR perfusion, stable xenon CT perfusion, and arterial spin labeled (ASL) perfusion imaging. This interest targets not only cerebrovascular disease but also nonischemic pathology, especially CNS neoplasms and associated treatment effects.

Selected Publications:

Wolf RL (Guest Editor): Essentials of Neuroradiology Radiol Clin North Am 44 (1): 2006.

Jones CE, Wolf RL, Detre JA, Das B, Saha PK, Wang J, Zhang Y, Song HK, Wright AC, Mohler, EM, III, Fairman RM, Zager EL, Velazquez OC, Golden MA, Carpenter JP, Wehrli FW: Characterization of hemispheric cerebral blood flow before and after carotid endarterectomy using unilateral arterial spin labeling. NMR Biomed 19 : 198-208,2006.

Wang S, Wolf RL, Woo JH, Wang J, O’Rourke DM, Roy S, Melhem ER, Poptani H: Actinomycotic Brain Infection: Registered Diffusion, Perfusion MR Imaging and MR Spectroscopy Neuroradiology 48 (5): 346-350,2006.

Wolf RL, Wang J, Wang S, Melhem ER, O’Rourke DM, Judy KD, Detre JA.: Grading of CNS Neoplasms Using Continuous Arterial Spin Labeled Perfusion MR Imaging at 3 Tesla J Magn Reson Imaging 22 : 475-482,2005.

Wolf RL, Wehrli SL, Popescu AM, Woo JH, Song HK, Wright AC, Mohler EM, III, Harding JD, Zager EL, Fairman RM, Golden MA, Velazquez OC, Carpenter JP, Wehrli FW.: Mineral volume and morphology in carotid plaque specimens using high resolution magnetic resonance imaging and computed tomography Arterioscler Thromb Vasc Biol 25 : 1729-1735,2005.

Wang J, Zhang Y, Wolf RL, Roc AC, Alsop DC, Detre JA.: Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study Radiology 235 : 218-228,2005.

Kasner SE, Sheth KN, Wu GF, Messe SR, Wolf RL: Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients Neurology 65 : 337-338,2005.

Wolf RL: Invited commentary for Nunez DB, Jr, Torres-Leon MT, Munera F. Vascular injuries of the neck and thoracic inlet: helical CT-angiographic correlation. Radiographics 2004;24:1087-1100 Radiographics 24 (4): 1099-1100,2004.

Sheth KN, Wu G, Messe SR, Wolf RL, Kasner SE: Dialysis disequilibrium: another reversible posterior leukoencephalopathy syndrome? Clinical Neurology and Neurosurgery 105 : 249-252,2003.

Academic Contact Info

University of Pennsylvania Medical Center
Department of Radiology
Section of Neuroradiology, 219 Dulles
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 349-5184
Fax: (215) 662-3283
Patient appointments: 800-789-PENN (7366)

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