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Ron C. Anafi, MD, PhD

Ron C. Anafi, MD, PhD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Anafi is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Sleep Medicine

Programs & Centers:

Board Certification:

  • Sleep Medicine (ABIM), 2009
  • Sleep Medicine (ABSM), 2009

Clinical Expertise:

  • Circadian Rhythm Disorders
  • Delayed Sleep Phase Syndrome (DSPD)
  • Excessive Daytime Sleepiness
  • Idiopathic Hypersomnolence
  • Insomnia
  • Narcolepsy
  • Restless Leg Syndrome (RLS)
  • Sleep Apnea
  • Sleep Disorders
  • Sleep Disorders in the Elderly
  • Sleep Study

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Minnesota Medical School
Residency: University of Vermont Medical Center
Fellowship: Hospital of the University of Pennsylvania

Memberships

Member, American Academy of Sleep Medicine, National Member, Society for Research on Biological Rhythms, National

Hospital Affiliation

Dr. Anafi is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Anafi RC, Francey LJ, Hogenesch JB, Kim J: CYCLOPS reveals human transcriptional rhythms in health and disease Proceedings of the National Academy of Sciences of the United States of America 114 (20): 5312-5317,2017.

Ruben Marc D, Wu Gang, Smith David F, Schmidt Robert E, Francey Lauren J, Lee Yin Yeng, Anafi Ron C, Hogenesch John B: A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine. Science translational medicine 10 (458): 2018.

Ben-Zvi Danny, Meoli Luca, Abidi Wasif M, Nestoridi Eirini, Panciotti Courtney, Castillo Erick, Pizarro Palmenia, Shirley Eleanor, Gourash William F, Thompson Christopher C, Munoz Rodrigo, Clish Clary B, Anafi Ron C, Courcoulas Anita P, Stylopoulos Nicholas: Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species. Cell metabolism 28 (2): 310-323.e6,2018.

Foteinou Panagiota T, Venkataraman Anand, Francey Lauren J, Anafi Ron C, Hogenesch John B, Doyle Francis J: Computational and experimental insights into the circadian effects of SIRT1. Proceedings of the National Academy of Sciences of the United States of America : 2018.

Krishnaiah SY, Wu G, Altman B, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM: Clock regulation of metabolites reveals coupling between transcription and metabolism Cell Metabolism 25 (4): 961-974.e4,2017.

Wu G, Anafi RC, Hughes ME, Kornacker K, Hogenesch JB: MetaCycle: an integrated R package to evaluate periodicity in large scale data. Bioinformatics 32 (21): 3351-3353,2016.

Zhang R, Podtelezhnikov AA, Hogenesch JB, Anafi RC: Discovering biology in periodic data through Phase Set Enrichment Analysis (PSEA) Journal of Biological Rhythms 31 (3): 244-257,2016.

Arnardottir ES, Nikonova EV, Shockley KR, Podtelezhnikov AA, Anafi RC, Tanis KQ, Maislin G, Stone DJ, Renger JJ, Winrow CJ, Pack AI: Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation. Sleep 37 (10): 1589-1600,2014.

Anafi RC, Lee Y, Sato TK, Venkataraman A, Ramanathan C, Kavakli IH, Hughes ME, Baggs JE, Growe J, Liu AC, Kim J, Hogenesch J: Machine learning helps identify CHRONO as a circadian clock component. PLoS Biology 12 (4): e1001840,2014.

Deckard A, Anafi RC, Hogenesch JB, Haase SB, Harer J: Design and analysis of large-scale biological rhythm studies: a comparison of algorithms for detecting periodic signals in biological data Bioinformatics (Oxford, England) 29 (24): 3174-3180,2013.

Academic Contact Info

Translational Research Laboratories, Suite 2100
125 South 31st Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)

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