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  • Britton Chance Professor of Radiology

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Gallagher E, Hou C, Zhu Y, Hsieh CJ, Lee H, Li S, Xu K, Henderson P, Chroneos R, Sheldon M, Riley S, Luk KC, Mach RH, McManus MJ. Positron Emission Tomography with [(18)F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy , Int J Mol Sci, 25: 2024,4943


Pees A, Tong J, Birudaraju S, Munot YS, Liang SH, Saturnino Guarino D, Mach RH, Mathis CA, Vasdev N. Development of Pyridothiophene Compounds for PET Imaging of α-Synuclein , Chemistry, 30: 2024,e202303921


Lee JY, Kim HY, Martorano P, Riad A, Taylor M, Luedtke RR, Mach RH. In vitro characterization of [(125)I]HY-3-24, a selective ligand for the dopamine D3 receptor , Front Neurosci, 18: 2024,1380009


Tian GL, Hsieh CJ, Taylor M, Lee JY, Luedtke RR, Mach RH. Design and Synthesis of D(3)R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies , Molecules, 29: 2023,123


Tian GL, Hsieh CJ, Taylor M, Lee JY, Riad AA, Luedtke RR, Mach RH. Synthesis of bitopic ligands based on fallypride and evaluation of their affinity and selectivity towards dopamine D(2) and D(3) receptors , Eur J Med Chem, 261: 2023,115751


Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy , J Med Chem, 66: 2023,12185-12202


Graham TJA, Lindberg A, Tong J, Stehouwer JS, Vasdev N, Mach RH, Mathis CA. In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers , J Med Chem, 66: 2023,10628-10638


Janssen B, Tian G, Lengyel-Zhand Z, Hsieh C-J, Loughee MG, Riad A, Xu K, Hou C, Weng C-C, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH Identification of a putative -synuclein radioligand using an in silico similarity search , Molecular Imaging and Biology , 25(4): 2023,704-719


Graham TJA, Lindberg A, Tong J, Stehouwer JS, Vasdev N, Mach RH, Mathis CA In silico discovery and subsequent characterization of potent 4R-tauopathy Positron Emission Tomography radiotracers , J. Med. Chem: 2023


Han QJ, Forfia P, Vaidya A, Ramani G, deKemp RA, Mach RH, Mankoff DA, Bravo PE, DiCarli M, Chan SY, Waxman AB, Han Y Effects of ranolazine on right ventricular function, fluid dynamics, and metabolism in patients with precapillary pulmonary hypertension: insights from a longitudinal, randomized, double-blind, placebo controlled, multicenter study , Front Cardiovasc Med, 10: 2023,1118796


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