About me
- Britton Chance Professor of Radiology
My Locations
Qualifications and experience
- Academy of Molecular Imaging, National
- American Association for Cancer Research, National
- American Chemical Society, National
- Divisions of Medicinal Chemistry, Organic Chemistry, and Fluorine Chemistry, National
- Neural Basis of Psychopathology, Addictions, and Sleep Disorders, National
- New York Academy of Sciences, Local
- Society for Neuroscience, National
- Society of Molecular Imaging, National
- Society of Nuclear Medicine, National
- Society of Nuclear Medicine and Molecular Imaging, National
- Society of Radiopharmaceutical Sciences, National
- Society of Radiopharmaceutical Sciences, International
- World Molecular Imaging Society, International
Treatments and Conditions
My research
Gallagher E, Hou C, Zhu Y, Hsieh CJ, Lee H, Li S, Xu K, Henderson P, Chroneos R, Sheldon M, Riley S, Luk KC, Mach RH, McManus MJ. Positron Emission Tomography with [(18)F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy , Int J Mol Sci, 25: 2024,4943
Pees A, Tong J, Birudaraju S, Munot YS, Liang SH, Saturnino Guarino D, Mach RH, Mathis CA, Vasdev N. Development of Pyridothiophene Compounds for PET Imaging of α-Synuclein , Chemistry, 30: 2024,e202303921
Lee JY, Kim HY, Martorano P, Riad A, Taylor M, Luedtke RR, Mach RH. In vitro characterization of [(125)I]HY-3-24, a selective ligand for the dopamine D3 receptor , Front Neurosci, 18: 2024,1380009
Tian GL, Hsieh CJ, Taylor M, Lee JY, Luedtke RR, Mach RH. Design and Synthesis of D(3)R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies , Molecules, 29: 2023,123
Tian GL, Hsieh CJ, Taylor M, Lee JY, Riad AA, Luedtke RR, Mach RH. Synthesis of bitopic ligands based on fallypride and evaluation of their affinity and selectivity towards dopamine D(2) and D(3) receptors , Eur J Med Chem, 261: 2023,115751
Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy , J Med Chem, 66: 2023,12185-12202
Graham TJA, Lindberg A, Tong J, Stehouwer JS, Vasdev N, Mach RH, Mathis CA. In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers , J Med Chem, 66: 2023,10628-10638
Janssen B, Tian G, Lengyel-Zhand Z, Hsieh C-J, Loughee MG, Riad A, Xu K, Hou C, Weng C-C, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH Identification of a putative -synuclein radioligand using an in silico similarity search , Molecular Imaging and Biology , 25(4): 2023,704-719
Graham TJA, Lindberg A, Tong J, Stehouwer JS, Vasdev N, Mach RH, Mathis CA In silico discovery and subsequent characterization of potent 4R-tauopathy Positron Emission Tomography radiotracers , J. Med. Chem: 2023
Han QJ, Forfia P, Vaidya A, Ramani G, deKemp RA, Mach RH, Mankoff DA, Bravo PE, DiCarli M, Chan SY, Waxman AB, Han Y Effects of ranolazine on right ventricular function, fluid dynamics, and metabolism in patients with precapillary pulmonary hypertension: insights from a longitudinal, randomized, double-blind, placebo controlled, multicenter study , Front Cardiovasc Med, 10: 2023,1118796