About me
- Britton Chance Professor of Radiology
My Locations
Qualifications and experience
- Academy of Molecular Imaging, National
- American Association for Cancer Research, National
- American Chemical Society, National
- Divisions of Medicinal Chemistry, Organic Chemistry, and Fluorine Chemistry, National
- Neural Basis of Psychopathology, Addictions, and Sleep Disorders, National
- New York Academy of Sciences, Local
- Society for Neuroscience, National
- Society of Molecular Imaging, National
- Society of Nuclear Medicine, National
- Society of Nuclear Medicine and Molecular Imaging, National
- Society of Radiopharmaceutical Sciences, National
- Society of Radiopharmaceutical Sciences, International
- World Molecular Imaging Society, International
Treatments and Conditions
My research
Stehouwer JS, Huang G, Saturnino Guarino D, Debnath ML, Polu A, Geib SJ, Lopresti B, Ikonomovic MD, Mason N, Mach RH, Mathis CA Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1 H-indoles as Tauopathy Positron Emission Tomography Radiotracers , Journal of Medicinal Chemistry, Vol 68/Issue 6: 2025 ,6462-6492
Dubroff JG, Hsieh CJ, Wiers CE, Lee H, Li EJ, Schubert EK, Mach RH, Kranzler HR [11C]Carfentanil PET Whole-Body Imaging of Mu-Opioid Receptors: A First In-Human Study , J. Nucl. Med, 66(1112-1118): 2025,1112-1118
Hsieh C-J, Saturnino Guarino D, Young AJ, Siderowf AD, Nasrallah I, Schmitz A, Garcia C, Kim HY, Schubert EK, Lee H, Perlmutter JS, Mach RH Pilot Study of [11C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer , Cells, 14(1157): 2025
Zhao H, Huang T, Dhavale DD, O’Shea JY, Lengyel-Zhand Z, Saturnino Guarino D, Gu J, Yue X, Nai Y-H, Jiang H, Lougee MG, Pagar VV, Kim HJ, Garcia BA, Petersson EJ, Mathis CA, Kotzbauer P, Perlmutter JS, Mach RH, Tu Z Discovery of N-(6-Methoxypyridin-3-yl)quinoline-2-amine Derivatives for Imaging Aggregated α-Synuclein in Parkinson's Disease with Positron Emission Tomography , Cells, 14(1108): 2025
Burström V, Xu K, Garro-Martínez E, Mach RH, Sahlholm K, Nibal Betari N A Nanoluciferase Complementation-based Assay for Monitoring β-arrestin2 Recruitment to the Dopamine D3 Receptor , Biochemistry and Biophysics Reports, 42(102019): 2025
Tian GL, Hsieh CJ, Guarino DS, Graham TJA, Lengyel-Zhand Z, Schmitz A, Chia WK, Young AJ, Crosby JG, Plakas K, Huang T, Jiang H, Yu Y, Hou C, Lee H, Petersson EJ, Giannakoulias S, O'Shea J, Kotzbauer P, Tu Z, Mathis CA, Mach RH The Development of a PET Radiotracer for Imaging Alpha Synuclein Aggregates in Parkinson’s Disease , RSC Med Chem , 10(1039): 2025
Li S, Schmitz A, Lu YT, Pal R, Sarkar S, Sellmyer MA, Mach RH, Lee H Evaluation of a Simplified Radiolabeling Method for a PARP Inhibitor in an Animal Model of Breast Cancer , EJNMMI Research , 15(50): 2025
Stehouwer JS, Huang G, Saturnino Guarino D, Debnath ML, Polu A, Geib SJ, Lopresti B, Ikonomovic MD, Mason N, Mach RH, Mathis CA Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1 H-indoles as Tauopathy Positron Emission Tomography Radiotracers , J Med. Chem, 68(6462-6492): 2025
Plakas K, Hsieh CJ, Guarino DS, Hou C, Chia WK, Young A, Schmitz A, Ho YP, Weng CC, Lee H, Li S, Graham TJA, Mach RH Toward a Small Molecule Antagonist Radioligand for Positron Emission Tomography Imaging of the Mu Opioid Receptor , ACS Chem. Neurosci, 16(1592-1603): 2025
Blizard GS, Dwivedi G, Pan YG, Hou C, Etersque JM, Said H, Chevrier A, Lavertu M, Ni H, Davis B, Tam Y, Cao Q, Mach RH, Weissman D, Alameh MG, Sellmyer MA. Monitoring mRNA vaccine antigen expression in vivo using PET/CT , Nature Communications, 16(1):2234: 2025