Penn Medicine Provider
About me
- Professor of Medicine (Gastroenterology)
Education and training
- Medical School: Johns Hopkins University School of Medicine
- Residency: Massachusetts General Hospital/Brigham and Women’s Hospital
- Fellowship: Massachusetts General Hospital/Brigham and Women’s Hospital
My Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: On the medical staff, but does not have privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Qualifications and experience
- American Association for the Study of Liver Diseases., National
- American Gastroenterological Association, National
- American Society for Cell Biology, National
- American Society for Matrix Biology, National
- Biophysical Society, National
- European Association for the Study of the Liver, International
My research
Ma S, Habash NW, Dehankar MK, Jalan-Sakrikar N, Cooper SA, Anwar AA, Jerez S, Sutthirat P, Gao J, Diamond T, Jiao J, Qiu C, Yang J, Ilyas SI, Lee M, Yaqoob U, Cao S, Wells RG, Shah VH, Hilscher MB Congestion enriches intra-hepatic macrophages through reverse zonation of CXCL9 in liver sinusoidal endothelial cells. , Cell Mol Gastroenterol Hepatol: 2025,101475
Byfield FJ, Eftekhari B, Kaymak-Loveless K, Mandal K, Li D, Wells RG, Chen W, Brujic J, Bergamaschi G, Wuite GJL, Patteson AE, Janmey PA Metabolically intact nuclei are fluidized by the activity of the chromatin remodeling motor BRG1. , Biophys J, 124(3): 2025,494-507
Fried S, Har-Zahav A, Hamudi Y, Mahameed S, Mansur R, Dotan M, Cozacov T, Shamir R, Wells RG, Waisbourd-Zinman O Biliary atresia: insights into mechanisms using a toxic model of the disease including Wnt and Hippo signaling pathways and microtubules. , Pediatric Research: 2024
Chen D, Du Y, Llewellyn J, Bonna A, Zuo B, Janmey PA, Farndale RW, Wells Rg Versican binds collagen via its G3 domain and regulates the organization and mechanics of collagenous matrices , Journal of Biological Chemistry, in press: 2024
Gupta K, Llewellyn J, Roberts E, Liu C, Naji A, Assoian RK, Wells RG The biliary atresia susceptibility gene EFEMP1 regulates extrahepatic bile duct elastic fiber formation and mechanics. , JHEP Reports, 7(1): 2024,101215
Chen D, Du Y, Llewellyn J, Bonna A, Zuo B, Janmey PA, Farndale RW, Wells RG. Versican binds collagen via its G3 domain and regulates the organization and mechanics of collagenous matrices , Journal of Biological Chemistry, 300(12): 2024,107968
Har-Zahav A, Tobar A, Fried S, Sivan R, Wilkins BJ, Russo P, Shamir R, Wells RG, Gurevich M, Waisbourd-Zinman O Oral N-acetylcysteine ameliorates liver fibrosis and enhances regenerative responses in Mdr2 knockout mice , Scientific Reports, 14: 2024,26513
Gupta K, Chen D, Wells RG Microcystin-RR is a biliary toxin selective for neonatal extrahepatic cholangiocytes. , JHEP Reports, 7(1): 2024,101218
Gupta K, XU JP, Diamond T, de Jong IEM, Glass A, Llewellyn J, Theise ND, Waisbourd-Zinman O, Winkler JD, Behrens EM, Mesaros C, Wells RG Low-dose biliatresone treatment of pregnant mice causes subclinical biliary disease in their offspring: Evidence for a spectrum of neonatal injury. , PLOS ONE, 19: 2024,e0301824
Braun J, Bernarding J, Snellings J, Meyer T, Dantas de Moraes PA, Safraou Y, Wells RG, Guo J, Tzschätzsch H, Zappe A, Pagel K, Sauer IM, Hillebrandt KH, Sack I On the relationship between viscoelasticity and water diffusion in soft biological tissues. , Acta Biomaterialia, 182: 2024,42-53