Description of Research Expertise:
Peter Reese, MD, MSCE is a transplant nephrologist and epidemiologist. He cares for patients at the Hospital of the University of Pennsylvania and the Philadelphia Veterans Affairs Medical Center.
His research focuses on: a) developing effective strategies to increase access to kidney transplantation, b) improving the process of selecting and caring for live kidney donors, c) determining outcomes of health policies on vulnerable populations with renal disease, including the elderly, and d) testing strategies to improve important health behaviors such as medication adherence. He directs Penn’s Center for Quality, Analytics and Research in Transplantation (PQART). He also chairs the Ethics Committee for the United Network for Organ Sharing (UNOS), which oversees organ allocation and transplant regulation in the United States. In recognition of his contributions to transplant research, he received a Presidential Early Career Award for Scientists and Engineers (PECASE) in July 2012. The PECASE "recognizes and supports scientists and engineers who show exceptional promise for leadership at the frontiers of scientific knowledge."
In the transplant field, Dr. Reese has written specifically about the ethical implications of accepting live kidney donors with risk factors for kidney disease, live donor outcomes, the effects of organ allocation policy on vulnerable subgroups including children and the elderly, and better strategies to promote the careful use of higher-risk organs (e.g., “medically complex donors”).
Dr. Reese’s mission encompasses energetic support of talented and motivated young researchers at all stages of training. This Lab’s success reflects their creativity and efforts.
Dr. Reese's research support has included funds generously provided by:
· The National Institutes of Health
· A T. Franklin Williams Award in geriatric research (co-sponsored by the Association of Specialty Professors and the American Society of Nephrology) to examine the effects of emerging organ allocation proposals on older kidney transplant candidates
· The American Society of Transplantation to study outcomes among older live kidney donors
· A Greenwall Faculty Scholars Grant to examine the ethical implications of novel methods to increase organ donor registration
· CVS-Caremark, Merck, and Humana to test innovative strategies for improving medication adherence
Additional information about Dr. Reese’s current research can be found here: http://www.med.upenn.edu/reeselab/
Description of Content-based Expertise
Renal Epidemiology, Organ Transplantation, Ethics”
Aubert O, *Reese PP, Audry B, Bouatou Y, Raynaud M, Viglietti D, Legendre C, Glotz D, Empana J-P, Jouven X, Lefaucheur C, Jacquelinet C, Alexandre Loupy: Disparities in the acceptance of deceased donor kidneys and consequences for transplant access: Nationwide analyses of practice in the US and France JAMA Internal Medicine : 2019, Accepted.
Sonnenberg EM, Cohen JB, Hsu JY, Potluri VS, Levine MH, Abt PL, Reese PP: Association of Kidney Transplant Center Volume With 3-Year Clinical Outcomes American Journal of Kidney Disease : 2019( Epub ahead of print).
Porrett PM, Reese PP, Holzmayer V, Coller KE, Kuhns M, Van Deerlin VM, Gentile C, Smith JR, Sicilia A, Woodards A, McLean R, Abt P, Bloom RD, Reddy KR, Blumberg E, Cloherty G, Goldberg D: Early Emergence of Anti-HCV Antibody Implicates Donor Origin in Recipients of an HCV-Infected Organ American Journal of Transplantation : 2019( Epub ahead of print).
McLean RC, *Reese PP, Acker M, Atluri P, Bermudez C, Goldberg LR, Abt PL, Blumberg EA, Van Deerlin VM, Reddy KR, Bloom RD, Hasz R, Suplee L, Sicilia A, Woodards A, Zahid MN, Bar KJ, Porrett P, Levine MH, Hornsby N, Gentile C, Smith J, Goldberg DS: Transplanting hepatitis C virus-infected hearts into uninfected recipients: A single-arm trial American Journal of Transplantation : 2019( Epub ahead of print).
Cohen JB, Potluri V, Porrett PM, Chen R, Roselli M, Shults J, Sawinski DL, Reese PP: Leveraging marginal structural modeling with Cox regression to assess the survival benefit of accepting vs declining kidney allograft offers American Journal of Transplantation : 2019( Epub ahead of print).
Sawinski D, Forde KA, Lo Re V 3rd, Goldberg DS, Cohen JB, Locke JE, Bloom RD, Brensinger C, Weldon J, Shults J, Reese PP: Mortality and Kidney Transplantation Outcomes Among Hepatitis C Virus-Seropositive Maintenance Dialysis Patients: A Retrospective Cohort Study American Journal of Kidney Disease : 2019 (epub ahead of print).
Hanson CS, Sautenet B, Craig JC, Chapman JR, Knoll G, Reese PP, Tong A: Informative for Decision-making? The Spectrum and Consistency of Outcomes Following Living Kidney Donation Reported in Trials and Observational Studies Transplantation 103 (2): 284-290,2019.
Mazur RD, Abt PL, Blumberg EA, Bloom RD, Reddy KR, Reese PP, Goldberg DS.: Characterization of early hepatic injury in HCV-negative recipients of HCV-infected kidneys Clinical Transplantation 33 (4): e13494,2019.
Cohen JB, Locke JE, Shelton B, Reed RD, Mustian M, MacLennan P, Forde KA, Reese PP, Sawinski D: Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus Clinical Transplantation 33 (2): e13466,2019.
Schröppel B, Heeger PS, Thiessen-Philbrook H, Hall IE, Doshi MD, Weng FL, Reese PP, Parikh CR: Donor Urinary C5a Levels Independently Correlate With Posttransplant Delayed Graft Function Transplantation 103 (1): e29-e35,2019.