Payman Zamani, MD, MTR
Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
Headshot of Payman Zamani, MD, MTR
Penn Medicine Provider

About me

  • Assistant Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania

Education and training

  • Medical School: Harvard Medical School
  • Residency: Mass General Brigham Healthcare Center - Chestnut Hill
  • Fellowship: UC San Diego Medical Center
  • Fellowship: University of Pennsylvania Health System

What my patients think about me

Average Rating

62 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
April 2026
have already recovered recommended dr zamani to several people
Anonymous
February 2026
clear communications
Anonymous
October 2025
he is a great doctor, he explains everything the way we understand
Anonymous
October 2025
takes the time to answer any and all questions completely and thoroughly. makes sure that i am aware of the things i need to know concerning my condition.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Zamani is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Benyard B, Mathur A, Roy D, Swain A, Kohkhar SK, Soni ND, Wilson N, Haris M, Zamani P, Reddy R, Kumar D Dual-Breathing CrCEST: A Novel Imaging Method to Distinguish Oxygen Delivery and Utilization in Exercised Muscle , International Society for Magnetic Resonance in Medicine, Cape Town, South Africa: 2026


Rosenbaum M, Allison KC, Laughlin MR, Kelley SS, Nunez-Matos J, Rickles M, Chau L, Wu G, Zamani P, Whyte KJ, Leibel RL, Hayes MR. The Physiology Of the WEight Reduced State (POWERS) study: strategies for the analysis of biological specimens. , Int J Obes (Lond): 2026


Cohen JB, Hossain A, Chittams J, Zhao M, Afable J, Greenip A, Maynard H, Pourmussa B, Prenner SB, Selvaraj S, Townsend RR, Zamani P, Chirinos JA. Calcium Channel Blockade versus Beta-Blockade for Hypertension in HFpEF: A Randomized Crossover Trial , Accepted for publication in Hypertension, May 2026: 2026


Lin KY, Bucha A, McSweeney K, Wade KL, Karaj A, Tamaroff J, O’Malley S, Chung NM, Cilenti NA, Wanner J, Adzika GK, Mesaros C, Rojsajjakul T, Blair IA, Serai S, Farmer J, Bryant K, Harhay MO, Lu Y, Paridon SM, Weber DR, Seifert W, Putt ME, Zamani P, Baur JA, Lynch DR, McCormack SE. Individualized exercise and NAD+ precursor supplementation in Friedreich’s Ataxia: a randomized controlled trial. , Lancet: Neurology, 25: 2026,469


Vidula MK, Schurgers LJ, Zhao L, Dib MJ, Zhao M, Wang Z, Ebert C, Salman O, Azzo JD, Zamani P, van Empel V, Richards AM, Doughty R, Javaheri A, Mann DL, Rietzschell E, Kammerhoff K, Schafer P, Seiffert DA, Ramirez-Valle F, Cappola TP, Chirinos JA Dephospho-Uncarboxylated Matrix Gla-Protein Is Associated With Adverse Outcomes in Heart Failure , Circ Heart Fail, 19: 2026,e012734


Vajargah KK, Dib MJ, Tavolinejad H, Zamani P, Richards AM, Mann DL, Rietzschel E, van Empel V, Burgess S, Cappola TP, Chirinos JA. Proteome-Wide Genetic Investigation of Kidney Function in Heart Failure With Preserved Ejection Fraction , JACC Heart Fail: 2025,102771


Saw EL, Werner LD, Cooper H, Pimental DR, Zamani P, Chirinos JA, Valero-Muñoz M, Sam F. Musclin Counteracts Skeletal Muscle Dysfunction and Exercise Intolerance in Heart Failure With Preserved Ejection Fraction , Circ Heart Fail, 18(6): 2025,e012350


Selvaraj S, Karaj A, Chirinos JA, Denney N, Grosso G, Fernando M, Chambers K, Demastus C, Reddy R, Langham M, Kumar D, Maynard H, Pourmussa B, Prenner SB, Cohen JB, Ischiropoulos H, Rickels MR, Poole DC, Church DD, Wolfe RR, Kelly DP, Putt M, Margulies KB, Zamani P Crossover Trial of Exogenous Ketones on Cardiometabolic Endpoints in Heart Failure with Preserved Ejection Fraction , JACC Heart Fail, 13(12): 2025,102435


Zamani P, Shah SJ, Cohen JB, Zhao M, Yang W, Afable JL, Caturla M, Maynard H, Pourmussa B, Demastus C, Mohanty I, Miyake MM, Adusumalli S, Margulies KB, Prenner SB, Poole DC, Wilson N, Reddy R, Townsend RR, Ischiropoulos H, Cappola TP, Chirinos JA Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial , JAMA Cardiol., 10(3): 2025,284


Selvaraj S, Karaj A, Chirinos JA, Denney N, Fernando M, Chambers K, Demastus C, Langham M, Maynard H, Pourmussa B, Prenner SB, Cohen J, Ischiropoulos H, Rickels M, Church D, Wolfe R, Kelly DP, Putt ME, Margulies KB, Zamani P. FUEL UTILIZATION DURING EXERCISE WITH EXOGENOUS KETONES VERSUS PLACEBO IN HEART FAILURE WITH PRESERVED EJECTION FRACTION: KETO-HFPEF , American College of Cardiology Annual Session, March 29-31, 2025; Chicago, IL.: 2025