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Patrick J. Brennan, MD

Patrick J. Brennan, MD Physician

Chief Medical Officer and Senior Vice President of the University of Pennsylvania Health System Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Brennan is employed by Penn Medicine.

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About Dr. Patrick J. Brennan

Recognized by Best Doctors in America 2003-2004

Recognized in Philadelphia Magazine's May 2002 Top Docs issue

Clinical Specialties

Board Certification:

  • Infectious Disease, 1990
  • Internal Medicine, 1985

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Temple University School of Medicine
Residency: Temple University Hospital
Fellowship: Hospital of the University of Pennsylvania


American Board of Internal Medicine, National American College of Physicians / American Society of Internal Medicine, National American Society of Microbiology, National Healthcare Improvement Foundation, National Infectious Diseases Society of America, National Joint Commission on Accreditation of Healthcare Organizations, National Pennsylvania Medical Society, National Pennsylvania Thoracic Society, National The College of Physicians of Philadelphia, Local The Philadelphia County Medical Society, Local The Society of Healthcare Epidemiology of America, National

Hospital Affiliation

Dr. Brennan is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Brennan PJ, Berns J: With Hahnemann's imminent closure, what happens to Physician trainees? The Philadelphia Inquirer : 2019.

Flores EJ, Mull NK, Lavenberg JG, Mitchell MD, Leas BF, Williams A, Brennan PJ, Umscheid CA: Using a 10-step framework to support the implementation of an evidence-based clinical pathways programme BMJ Qual Saf 28 (6): 476-485,2019.

Mahoney K, Brennan PJ: Hahnemann’s Closure: Community vs Advanced Care is a False Choice NEJM : 2019.

Sangal RB, Brennan PJ: Life Outside the Bubble: Opportunities for Diverse Resident Training with Consolidation of Health Systems EM News : 2018.

Brennan PJ, Channamsetty V: Innovations: A Modern Approach to Interprofessional Collaboration Healthcare Executive 33 (6): 50-51,2018.

Brennan PJ: An Update on Fluoroquinolones: The Emergence of a Multisystem Toxicity Syndrome PracticeUpdate : 2018.

Brennan PJ: Leadership in an ever-changing healthcare system Penn HeatlhX Podcast : 2017.

Sedrak MS, Myers JS, Small DS, Nachamkin I, Ziemba JB, Murray D, Kurtzman GW, Zhu J, Wang W, Mincarelli D, Danoski D, Wells BP, Berns JS, Brennan PJ, Hanson CW, Dine CJ, Patel MS: Effect of a Price Transparency Intervention in the Electronic Health Record on Clinician Ordering of Inpatient Laboratory Tests: The PRICE Randomized Clinical Trial JAMA Intern Med 177 (7): 939-945,2017.

Jayakumar KL, Lavenberg JA, Mitchell MD, Doshi JA, Leas B, Goldmann DR, Williams K, Brennan PJ, Umscheid CA: Evidence Synthesis Activities of a Hospital Evidence-based Practice Center and Impact on Hospital Decision Making J Hosp Med : 185-92,2016.

Brennan PJ: Incentivizing “structures” over “outcomes” to bridge the knowing-doing gap Podcast Interview : 2015.

Academic Contact Info

University of Pennsylvania Health System
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard, Suite 5A

Philadelphia, PA 19104
Phone: (215) 615-0668

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