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Pablo Tebas, MD

Pablo Tebas, MD Physician

Director & Principal Investigator, AIDS Clinical Trial Unit (ACTU) research site, University of Pennsylvania Director, Developmental Core, Penn Center for AIDS Research Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Tebas is employed by Penn Medicine.

About Dr. Pablo Tebas

Recognized by Best Doctors in America 2007 - 2012, 2015 - 2018

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Infectious Diseases

Programs & Centers:

Board Certification:

  • Infectious Disease, 2005
  • Internal Medicine, 2004

Clinical Expertise:

  • Aspergillosis
  • Bone Infection (Osteomyelitis)
  • C. Difficile (Clostridium Difficile Diarrhea)
  • Cellulitis
  • Flu (Influenza)
  • Flu Shot Vaccination
  • Genital Warts (Condyloma Acuminatum)
  • Hepatitis
  • Hepatitis B
  • Hepatitis C
  • Herpes Simplex Virus (HSV)
  • HIV and AIDS
  • Joint Infection
  • Lyme Disease
  • Malaria
  • Meningitis
  • Mycobacterium
  • Pneumonia
  • Prosthetic Joint Infection
  • Sexually Transmitted Diseases (STD)
  • Shingles
  • Staph Infection
  • Swollen Lymph Nodes
  • Syphilis
  • Travelers' Diarrhea
  • Tuberculosis (TB)
View More

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Universidad Autonoma De Madrid
Fellowship: Barnes-Jewish Hospital - Washington University, St. Louis


American Society for Microbiology (ASM), National Department of Health and Human Services (DHHS), National HIV Medical Association (HIVMA-IDSA), National Infectious Diseases Society of America (IDSA), National International AIDS Society, International International AIDS Society-USA, National NIH, Division of AIDS, AIDS Clinical Trial Group, National Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (Spanish Society of Infectious Diseases and Clinical Microbiology), National Sociedad Española de Medicina Interna (Spanish Society of Internal Medicine), National

Hospital Affiliation

Dr. Tebas is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My research interests center around the study of the complications of HIV and its treatment, and currently in the evaluation of strategies for the cure of HIV infection.
I am the director and the PI of the AIDS clinical trial unit of the University of Pennsylvania.
I am one of the founding members of the HIV Reservoirs and Viral Eradication (Cure) Transformative Science Group (TSG) of the AIDS clinical trial group. In addition to my ACTG work, I am involved (as PI of the clinical project) in several early phase trials of new compounds developed in conjunction with the NIH in several IPCP grants, including a Phase I study evaluating the antiviral activity of aprepitant (an NK-1R antagonist that down-regulates the expression of CCR5), a phase I study evaluating the immunogenicity of a therapeutic DNA vaccine administered by intramuscular electroporation in collaboration with David Weiner and several gene therapy studies evaluating the therapeutic use of lentiviral vectors in the management of HIV infection (including the use of VIRxSYS 496 –antisense approach-, the first in humans Sangamo’s zinc finger nuclease for CCR5 edition, in collaboration with Dr. Carl June.

Selected Publications:

Bertagnolli, L. N., White, J. A., Simonetti, F. R., Beg, S. A., Lai, J., Tomescu, C., Murray, A. J., Antar, A. A. R., Zhang, H., Margolick, J. B., Hoh, R., Deeks, S. G., Tebas, P., Montaner, L. J., Siliciano, R. F., Laird, G. M., Siliciano, J. D.: The role of CD32 during HIV-1 infection Nature 561 (7723): E17-E19,2018.

Namazi, G., Fajnzylber, J. M., Aga, E., Bosch, R., Acosta, E. P., Sharaf, R., Hartogensis, W., Jacobson, J. M., Connick, E., Volberding, P., Skiest, D., Margolis, D., Sneller, M. C., Little, S. J., Gianella, S., Smith, D., Kuritzkes, D. R., Gulick, R. M., Mellors, J. W., Mehraj, V., Gandhi, R. T., Mitsuyasu, R., Schooley, R. T., Henry, K., Tebas, P., Deeks, S., Chun, T. W., Collier, A. C., Routy, J. P., Hecht, F. M., Walker, B. D., Li, J. Z.: The Control of HIV after Antiretroviral Medication Pause (CHAMP) study: post-treatment controllers identified from 14 clinical studies J Infect Dis : doi: 10.1093/infdis/jiy479,2018.

Salantes, D. B., Zheng, Y., Mampe, F., Srivastava, T., Beg, S., Lai, J., Li, J. Z., Tressler, R. L., Koup, R. A., Hoxie, J., Abdel-Mohsen, M., Sherrill-Mix, S., McCormick, K., Overton, E. T., Bushman, F. D., Learn, G. H., Siliciano, R. F., Siliciano, J. M., Tebas, P., Bar, K. J.: HIV-1 latent reservoir size and diversity are stable following brief treatment interruption J Clin Invest 128 (7): 3102-3115,2018.

LaFleur, J., Bress, A. P., Myers, J., Rosenblatt, L., Crook, J., Knippenberg, K., Bedimo, R., Tebas, P., Nyman, H., Esker, S.: Tenofovir-Associated Bone Adverse Outcomes among a US National Historical Cohort of HIV-Infected Veterans: Risk Modification by Concomitant Antiretrovirals Infect Dis Ther 7 (2): 293-308,2018.

Bedimo, R. J., Adams-Huet, B., Poindexter, J., Brown, G., Farukhi, I., Castanon, R., Turner, D., Moore, T., Tebas, P., Maalouf, N. M.: The Differential Effects of Human Immunodeficiency Virus and Hepatitis C Virus on Bone Microarchitecture and Fracture Risk Clin Infect Dis 66 (9): 1442-1447,2018.

Abdel-Mohsen, M., Kuri-Cervantes, L., Grau-Exposito, J., Spivak, A. M., Nell, R. A., Tomescu, C., Vadrevu, S. K., Giron, L. B., Serra-Peinado, C., Genesca, M., Castellvi, J., Wu, G., Del Rio Estrada, P. M., Gonzalez-Navarro, M., Lynn, K., King, C. T., Vemula, S., Cox, K., Wan, Y., Li, Q., Mounzer, K., Kostman, J., Frank, I., Paiardini, M., Hazuda, D., Reyes-Teran, G., Richman, D., Howell, B., Tebas, P., Martinez-Picado, J., Planelles, V., Buzon, M. J., Betts, M. R., Montaner, L. J.: CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells Sci Transl Med 10 (437): 2018.

Benson, C. A., Andersen, J. W., Macatangay, B. J. C., Mailliard, R. B., Rinaldo, C. R., Jr., Read, S., Bozzolo, D. R., Purdue, L., Jennings, C., Keefer, M. C., Glesby, M., Tebas, P., Russell, A. F., Martin, J., Annunziato, P., Popmihajlov, Z., Lennox, J. L.: Safety and Immunogenicity of Zoster Vaccine Live in HIV-Infected Adults with CD4+ Cell Counts Above 200 Cells/mL Virologically Suppressed on Antiretroviral Therapy Clin Infect Dis. : 10.1093/cid/ciy242,2018.

Kudchodkar, S. B., Choi, H., Reuschel, E. L., Esquivel, R., Jin-Ah Kwon, J., Jeong, M., Maslow, J. N., Reed, C. C., White, S., Kim, J. J., Kobinger, G. P., Tebas, P., Weiner, D. B., Muthumani, K.: Rapid response to an emerging infectious disease - Lessons learned from development of a synthetic DNA vaccine targeting Zika virus Microbes Infect : 2018.

LaFleur, J., Bress, A. P., Esker, S., Knippenberg, K., Crook, J., Nyman, H., Bedimo, R., Tebas, P., Rosenblatt, L.: Brief Report: Tenofovir-Associated Nephrotoxicity Among a US National Historical Cohort of HIV-Infected Veterans: Risk Modification by Concomitant Antiretrovirals J Acquir Immune Defic Syndr 77 (3): 325-330,2018.

Bedimo, R. J., Adams-Huet, B., Poindexter, J., Brown, G., Farukhi, I., Castanon, R., Turner, D., Moore, T., Tebas, P., Maalouf, N. M.: The Differential Effects of HIV and HCV on Bone Micro-Architecture and Fracture risk Clin Infect Dis : 2017.

Academic Contact Info

Academic Address: 502 Johnson Pavilion
Clinical Office: 4 Perelman Center for Advanced Medicine, 3600 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 349-8092
Patient appointments: 800-789-7366 (PENN)

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