L K Metthew Lam, Nathan J Klingensmith, Layal Sayegh, Emily Oatman, Joshua S Jose, Christopher V Cosgriff, Kaitlyn A Eckart, John McGinnis, Piyush Ranjan, Matthew Lanza, Nadir Yehya, Nuala J Meyer, Robert P Dickson, Nilam S Mangalmurti Red Blood Cells Capture and Deliver Bacterial DNA to Drive Host Responses During Polymicrobial Sepsis , J Clin Invest
: 2025
L.K. Metthew Lam, Sophia Murphy, Dimitra Kokkinaki, Alessandro Venosa, Scott Sherrill-Mix, Carla Casu, Stefano Rivella, Aaron Weiner, Jeongho Park, Sunny Shin, Andrew Vaughan, Beatrice H. Hahn, Audrey R. Odom John, Nuala J. Meyer, Christopher A. Hunter, G. Scott Worthen, Nilam S. Mangalmurti DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia , Science Translational Medicine, 13(616): 2021
Yehya N, Booth TJ, Ardhanari GD, Thompson JM, Lam LKM, Till JE, Mai MV, Keim G, McKeone DJ, Halstead ES, Lahni P, Varisco BM, Zhou W, Carpenter EL, Christie JD, Mangalmurti NS. Inflammatory and tissue injury marker dynamics in pediatric acute respiratory distress syndrome , J Clin Invest: 2024
Metthew Lam LK, Oatman E, Eckart KA, Klingensmith NJ, Flowers E, Sayegh L, Yuen J, Clements RL, Meyer NJ, Jurado KA, Vaughan AE, Eisenbarth SC, Mangalmurti NS Human red blood cells express the RNA sensor TLR7 , Scientific Reports: 2024
Thompson JC, Li S, Jose JS, Predina J, Gupta A, Eruslanov E, Singhal S, Albelda SM, Mangalmurti NS. Red blood cells function as reservoirs of tumor DNA , Am J Physiol Lung Cell Mol Physiol, 326: 2024,L646-L650
Meghan J. Hotz, Danielle Qing, Michael G. S. Shashaty, Peggy Zhang, Hilary Faust, Neal Sondheimer, Stefano Rivella, G. Scott Worthen, and Nilam S. Mangalmurti Red Blood Cells Homeostatically Bind Mitochondrial DNA through TLR9 to Maintain Quiescence and to Prevent Lung Injury. , American Journal of Respiratory and Critical Care Medicine, 197(4): 2018,470-480
Qing D, Conegliano D, Shashaty MG, Seo J, Reilly JP, Worthen GS, Huh D, Meyer NJ, Mangalmurti NS. Red Blood Cells Induce Necroptosis of Lung Endothelial Cells and Increase Susceptibility to Lung Inflammation , American Journal of Respiratory and Critical Care Medicine, 190(11): 2014,1243-54
L K Metthew Lam, Jane Dobkin, Kaitlyn A Eckart, Ian Gereg, Andrew DiSalvo, Amber Nolder, Eman Anis, Julie C Ellis, Greg Turner, Nilam S Mangalmurti Bat Red Blood Cells Express Nucleic Acid-Sensing Receptors and Bind RNA and DNA , Immunohorizons, 6(5): 2022,299-306
Michael G. S. Shashaty, MD, MSCE; John P. Reilly, M.D., M.S.C.E.; Hilary E. Faust, M.D.; Caitlin M. Forker, B.A.; Caroline A. G. Ittner, Ph.D.; Peggy X. Zhang, B.S.; Meghan J. Hotz, B.S.; David Fitzgerald; Wei Yang, Ph.D.; Brian J. Anderson, M.D., M.S.C.E.; Daniel N. Holena, MD, MSCE; Paul N. Lanken, M.D., M.S.C.E.; Jason D. Christie, M.D., M.S.C.E.; Nuala J. Meyer, MD, MS; Nilam S. Mangalmurti, M.D. Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study , Critical Care, 23(1): 2019,235 published on-line
Mangalmurti Nilam S, Xiong Zeyu, Hulver Mei, Ranganathan Mrunalini, Liu Xiang Hong, Oriss Timothy, Fitzpatrick Meghan, Rubin Marc, Triulzi Darrell, Choi Augustine, Lee Janet S Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation. , Blood, 113(5): 2009,1158-66
