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Neil R. Malhotra, MD

Neil R. Malhotra, MD Physician

Co-Director, Translational Spine Research Lab Director, Neurosurgery Quality Improvement Initiative Vice Chairman for Operations, Department of Neurosurgery Associate Professor of Orthopaedic Surgery Associate Professor of Neurosurgery at the Hospital of the University of Pennsylvania

Languages spoken:

  • Spanish

Dr. Malhotra is employed by Penn Medicine.

About Dr. Neil R. Malhotra

Recognized in Philadelphia magazine's May 2019 Top Docs issue

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Neurosurgery

Programs & Centers:

Board Certification:

  • Neurological Surgery, 2015

Clinical Expertise:

  • Abnormal Vertebrae
  • Absent Vertebrae
  • Acoustic Neuroma (Vestibular Schwannoma)
  • Aneurysms
  • Ankylosing Spondylitis
  • Anterior Vertebral Body Tethering
  • Arteriovenous Malformations (AVM)
  • Artificial Disc Replacement Surgery in the Cervical Spine
  • Artificial Disc Replacement Surgery in the Lumbar Spine
  • Auditory Brainstem Implant
  • Back Injuries
  • Back Surgery
  • Biological Enhancement of Spinal Fusion
  • Bone Cyst
  • Bone Growth Stimulator
  • Bone Tumors
  • Brachial Plexus Injury
  • Brain Metastasis
  • Brain Surgery
  • Brain Tumors
  • Broken Coccyx
  • Bulging Disc
  • Cauda Equina Syndrome
  • Cerebrospinal Fluid (CSF) Leak
  • Cervical Arthritis
  • Cervical Bone Spur
  • Cervical Compression Fracture
  • Cervical Decompression
  • Cervical Deformity
  • Cervical Disc Degeneration
  • Cervical Disc Disease
  • Cervical Disc Displacement
  • Cervical Disc Herniation
  • Cervical Laminoplasty
  • Cervical Laminotomy
  • Cervical Radiculopathy
  • Cervical Revision Surgery
  • Cervical Spinal Fracture
  • Cervical Spinal Fusion Surgery
  • Cervical Spinal Stenosis
  • Cervical Spine Surgery
  • Cervical Steroid Injection
  • Cholesteatoma
  • Chordoma
  • Coccyx Injury
  • Complex Spinal Deformities
  • Complex Spinal Surgery
  • Compression Fractures
  • Congenital Malformation of the Spine
  • Congenital Scoliosis
  • Cordotomy
  • Corpus Callosotomy Surgery
  • Craniocervical Junction Surgery
  • Craniopharyngioma
  • Craniotomy
  • Decompression Laminectomy
  • Decompression Median Nerve At Elbow
  • Deep Brain Stimulation
  • Degenerative Spine Conditions
  • Disc Arthroplasty
  • Disc Replacement
  • Disc Surgery
  • Diskectomy
  • Dorsal Column Stimulator
  • Dystonia
  • Endoscopic Fusion
  • Epidural Injection
  • Epilepsy
  • Epilepsy Surgery
  • Essential Tremor
  • Extreme Lateral Interbody Fusion
  • Facet Injection
  • Facet Surgery
  • Failed Back Surgery Syndrome (FBSS)
  • Flatback Syndrome Post Harrington Rods
  • Foot Drag
  • Gamma Knife
  • Germ Cell Tumors
  • Glioblastoma
  • Growing Rods
  • Head and Neck Osteoma
  • Herniated Disc
  • Intraspinal Abscess
  • Junctional Kyphosis
  • Juvenile Nasopharyngeal Angiofibroma (JNA)
  • Kyphosis
  • Laminectomy
  • Laminoplasty
  • Lateral Access Spine Surgery
  • Lesion of Popliteal Nerve
  • Lesion of Posterior Tibial Nerve
  • Lesion of Sciatic Nerve
  • Low Back Surgery
  • Lower Back Injuries
  • Lower Back Pain
  • Lumbar Scoliosis
  • Lumbar Spinal Fracture
  • Lumbar Spinal Fusion
  • Lumbar Spinal Injury
  • Lumbar Spinal Mass
  • Lumbar Spinal Stenosis
  • Lumbar Spinal Tumor
  • Lumbar Stress Fracture
  • Lumbosacral Plexus Lesion
  • Lumbosacral Radiculopathy
  • Microdiscectomy
  • Microsurgery
  • Microvascular Decompression
  • Minimally Invasive Partial Lumbar Discectomy
  • Minimally Invasive Spinal Fusion
  • Minimally Invasive Spine Surgery
  • Minimally Invasive Surgery
  • Myelopathy
  • Myelopathy Surgery
  • Neck Masses and Lumps
  • Neck Tumors
  • Neurocutaneous Disorders
  • Neuroendocrine Tumors
  • Neurofibromatosis Type 1 (NF1)
  • Neurogenic Claudication
  • Neuromuscular Scoliosis
  • Occipito-Cervical Fusion
  • Orbital Tumors
  • Osteoarthritis of the Spine
  • Parkinson's Disease
  • Peripheral Nerve Disorders
  • Peripheral Nerve Tumors
  • Pituitary Surgery
  • Pituitary Tumors
  • Posterior Cervical Laminectomy and Fusion
  • Posterior Lumbar Laminectomy
  • Post-Laminectomy Kyphosis
  • Post-Laminectomy Syndrome
  • Prolactinoma
  • Radiculopathy
  • Revision of Spinal Surgery
  • Rhizotomy
  • Robotic Spine Surgery
  • Ruptured Intervertebral Disc
  • Sacral Nerve Stimulation
  • Sacroiliac Joint Block
  • Sacroiliac Joint Fusion
  • Sacroiliac Joint Surgery
  • Scheuermann Disease
  • Scheuermann's Kyphosis
  • Sciatica
  • Scoliosis Surgery
  • Selective Dorsal Rhizotomy
  • Skull Base Tumors
  • Spina Bifida
  • Spinal Abscess
  • Spinal Abscess Surgery
  • Spinal Cord Cancer
  • Spinal Cord Compression
  • Spinal Cord Disorder
  • Spinal Cord Stimulator
  • Spinal Cord Surgery
  • Spinal Cyst Removal
  • Spinal Deformity
  • Spinal Dural Graft
  • Spinal Fracture
  • Spinal Fusion
  • Spinal Mass
  • Spinal Meningioma
  • Spinal Microsurgery
  • Spinal Reconstruction
  • Spinal Schwannoma
  • Spinal Stenosis
  • Spinal Tethering for Scoliosis
  • Spinal Tumor
  • Spine Decompression
  • Spine Deformity
  • Spine Deformity Correction Surgery
  • Spine Injuries
  • Spine Stapling
  • Spondylectomy
  • Spondyloarthropathy
  • Spondylolisthesis
  • Spondylosis
  • Spondylosis Surgery
  • Spondylosis With Myelopathy
  • Spondylosyndesis
  • Stereotactic Radiosurgery
  • Surgery for Sciatica
  • Surgical Treatment of Myelopathy
  • Tarlov Cysts
  • Tethered Spinal Cord
  • Thoracic Disc Herniation
  • Thoracic Laminectomy
  • Thoracic Spinal Fracture
  • Thoracic Spinal Fusion
  • Thoracic Spinal Injury
  • Thoracic Spinal Mass
  • Thoracic Spinal Stenosis
  • Thoracic Spinal Tumor
  • Trigeminal Nerve Disorders
  • Ulnar Nerve Decompression
  • Ulnar Nerve Surgery
  • Vascular Malformations of the Spine
  • Vertebrae Surgery
  • Vertebral Epiphysitis
  • Vertebral Fracture
  • Vertebral Stapling
  • Visualase MRI-Guided Laser Ablation
  • X-Stop Surgery
View More

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Virginia
Residency: Hospital of the University of Pennsylvania

Memberships

American Association of Neurological Surgeons, National AO Spine Educational Association, International Congress of Neurological Surgeons, National North American Spine Society, International Pennsylvania Neurosurgical Society, Local Section for the Spine and Peripheral Nerves, American Association of Neurological Surgeons/Congress of Neurological Surgeons, National Section on History of Neurological Surgery, American Association of Neurological Surgeons, National

Hospital Affiliation

Dr. Malhotra is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

As Co-Director of the Translational Spinal Research Laboratory (TSRL), Dr. Malhotra's primary research interests focus on restorative approaches to treat disc degeneration. His novel approaches have led to multiple awards and research grants. Through his work, Dr. Malhotra hopes to reduce the need for spinal surgery and offer better treatments for disc degeneration. His interests focus on tissue engineering in order to develop treatments to restore native tissue mechanics of the spine while also delivering therapeutic agents and supporting tissue regeneration.

Selected Publications:

Agarwal, P., Ramayya, AG., Osiemo, B., Goodrich, S., Glauser, G., McClintock, SD., Chen, HI., Schuster, JM., Grady, MS., Malhotra, NR: Association of Overlapping Neurosurgery with Patient Outcomes at a Large Academic Medical Center American Association of Neurological Surgeons : 2019.

Caplan IF, Zadnik P, Glauser G, Ali ZS, O’Rourke DM, Kung DK, Choudhri O, Osiemo B, Goodrich S, McClintock SD, Malhotra NR: The LACE+ index as a predictor of 30-day readmission in a brain tumor population American Association of Neurological Surgeons : 2019.

Caplan, IF., Sullivan, PZ., Glauser, G., Choudhri, O., Kung, D., O’Rourke, DM., Osiemo, B., Goodrich, S., McClintock, SD., Malhotra, NR: The LACE+ index fails to predict 30-90 day readmission for supratentorial craniotomy patients Clin Neurol Neurosurg : 2019.

Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Vollmer, C., DeMatteo, R., Malhotra, NR: Association of Overlapping, Non-Concurrent, Surgery with Patient Outcomes at a Large Academic Medical Center: A Coarsened Exact Matching Study American Surgical Association 139th Annual Meeting : 2019.

Peck, SH., Bendigo, JR., Tobias, JW., Dodge, GR., Malhotra, NR., Mauck, RL., Smith, LJ: Hypoxic Preconditioning Enhances Bone Marrow-Derived Mesenchymal Stem Cell Survival in a Low Oxygen and Nutrient-Limited 3D Microenvironment Cartilage : 2019.

Caplan, IF., Sinha, S., Osiemo, B., McClintock, SD., Schuster, JM., Smith, H., Glauser, G., Sharma, N., Ozturk, AK., Ali, ZS., Malhotra, NR: The utility of cervical spine bracing as a postoperative adjunct to multilevel anterior cervical spine surgery International Journal of Spine Surgery-in press : 2019.

Sinha, S., Caplan, IF., Schuster, JM., Piazza, M., Glauser, G., Sharma, N., Welch, WC., Osiemo, B., McClintock, SD., Ozturk, AK., Malhotra, NR: Evaluation of lumbar spine bracing as a postoperative adjunct to single-level posterior lumbar spine surgery World Neurosurgery-in press : 2019.

Caplan, IF., Glauser, G., Goodrich, S., Chen, HI., Lucas, TH., Lee, JYK., McClintock, SD., Malhotra, NR: Undiagnosed obstructive sleep apnea as a predictor of 30-day readmission for brain tumor patients Journal of Neurosurgery : 2019.

Glauser, G., Piazza, M., Berger, I., Osiemo, B., McClintock, SD., Winter, E., Chen, HI., Ali, ZS., Malhotra, NR: The Risk Assessment and Prediction Tool (RAPT) for Discharge Planning in a Posterior Lumbar Fusion Population Neurosurgery-in press : 2019.

Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Vollmer, C., DeMatteo, R., Malhotra, NR: Association of Overlapping, Non-Concurrent, Surgery with Patient Outcomes at a Large Academic Medical Center: A Coarsened Exact Matching Study Annals of Surgery : 2019.

Hitti FL, McShane BJ, Yang AI, Rinehart C, Albayar A, Branche M, Malhotra NR, Janjua MB, Ali ZS, Schuster JM, Ozturk AK: Predictors of Failure of Nonoperative Management Following Subaxial Spine Trauma and Creation of Modified Subaxial Injury Classification System World Neurosurg : 2019.

Ramayya, AG., Glauser, G., Mcshane, B., Branche, M., Sinha, S., Kvint, S., Buch, V., Abdullah, KG., Kung, DK., Chen, HI., Malhotra, NR., Ozturk, AK: Factors Predicting Ventriculostomy Revision at a Large Academic Medical Center World Neurosurgery : e509-e514,2019.

Petrov, D., Spadola, M., Berger, C., Glauser, G., Mahmoud, A., O’Malley, B., Malhotra, NR: Novel Approach using Ultrasonic Bone Curettage and TransOral Robotic Surgery for En Bloc Resection of Cervical Spine Chordoma J Neurosurg Spine : 2019.

Ali ZS, Flanders TM, Ozturk AK, Malhotra NR, Leszinsky L, McShane BJ, Gardiner D, Rupich K, Chen HI, Schuster J, Marcotte PJ, Kallan MJ, Grady MS, Fleisher LA, Welch WC: Enhanced recovery after elective spinal and peripheral nerve surgery: pilot study from a single institution J Neurosurg Spine : 2019.

Caplan, IF., Sullivan, PZ., Kung, D., O’Rourke, DM., Choudhri, O., Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Malhotra, NR: The LACE+ index as a predictor of 30-day readmission in a brain tumor population World Neurosurgery : 2019.

Jivraj, I., Liu, GT., Sharma, N., Glauser, G., Grady, MS., Malhotra, NR: Resolution of Papilledema associated with Chiari I Malformation with Ventriculoperitoneal Shunting Asian J Neurosurg : 598-601,2019.

Caplan, IF., Sinha, S., Schuster, JM., Piazza, M., Glauser, G., Osiemo, B., McClintock, SD., Welch, WC., Sharma, N., Ozturk, AK., Malhotra, NR: The utility of cervical spine bracing as a postoperative adjunct to single-level anterior cervical spine surgery Asian J Neurosurg 14 : 461-66,2019.

Glauser, G., Agarwal, P., Ramayya, AG., Chen, HI., Lee, JYK., Schuster, JM., Osiemo, B., Goodrich, S., Smith, LJ., McClintock, SD., Malhotra, NR: Association of Surgical Overlap During Wound Closure with Patient Outcomes Amongst Neurological Surgery Patients at a Large Academic Medical Center Neurosurgery : 2019.

Agarwal, P., Ramayya, AG., Osiemo, B., Goodrich, S., Glauser, G., McClintock, SD., Chen, HI., Schuster, JM., Grady, MS., Malhotra, NR: Association of Overlapping Neurosurgery with Patient Outcomes at a Large Academic Medical Center Neurosurgery : 2019.

Ramayya, AG., Chen, HI., Marcotte, PJ., Brem, S., Zager, EL., Osiemo, B., Piazza, M., Sharma, N., McClintock, SD., Schuster, JM., Ali, ZS., Connolly, P., Heuer, GG., Grady, MS., Kung, DK., Ozturk, AK., O’Rourke, DM., Malhotra, NR: Assessing variability in surgical decision making among attending neurosurgeons at an academic center J Neurosurg : 2019.

Berger, I., Piazza, M., Sharma, N., Glauser, G., Osiemo, B., McClintock, SD., Lee, JYK., Schuster, JM., Ali, ZS., Malhotra, NR: Evaluation of the Risk Assessment and Prediction Tool for Post-Operative Disposition Needs After Cervical Spine Surgery Neurosurgery : 2019.

Malhotra NR, Piazza M, Demoor R, McClintock SD, Hamilton K, Sharma N, Osiemo B, Berger I, Hossain E, Borovskiy Y, Maloney E, Smith LJ, Grady MS: Impact of reduced pre-incision antibiotic infusion time on surgical site infection rates: a retrospective cohort study Annals of Surgery : 2018.

Piazza M, Peck SH, Gullbrand SE, Bendigo JR, Arginteanu T, Zhang Y, Smith HE, Smith LJ (co-corresponding), Malhotra NR: Quantitative MRI correlates with histological grade in a percutaneous needle injury mouse model of disc degeneration J Orthop Res : 2018.

Piazza M, Sharma N, Osiemo B, McClintock S, Missimer E, Gardiner D, Maloney E, Callahan D, Smith JL, Welch W, Schuster J, Grady MS, Malhotra NR: Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population Neurosurgery : 2018.

Goel NJ, Agarwal P, Mallela AN, Abdullah KG, Ali ZS, Ozturk AK, Malhotra NR, Schuster JM, Chen HI: Liver disease is an independent predictor of poor 30-day outcomes following surgery for degenerative disease of the cervical spine Spine J : 2019.

Nayak NR, Stephen JH, Piazza MA, Obayemi AA, Stein SC, Malhotra NR: Quality-of-Life in Patients Undergoing Spine Surgery: Systematic Review and Meta-Analysis Global Spine J : 2019.

Christian Terwiesch: Cobotics in Surgery-En Bloc Resection of Spinal Cancers Sirius XM: Wharton Business Radio : 2018.

Zadnik-Sullivan P, Sanborn M, Smith LJ, Malhotra NR: Spinal Cord and Spinal Column The Trauma Manual: Trauma and Acute Care Surgery 5th Edition-in press : 2018.

Smith LJ, Silverman L, Sakai D, Lotz JC, Le Maitre CL, Malhotra NR, Mauck RL, Buckley CT: Advancing Cell Therapies for Intervertebral Disc Regeneration from the Lab to the Clinic: Recommendations of the ORS Spine Section JOR Spine : 2018.

Baker M, Malhotra NR: En Bloc Spondylectomy and Trans Oral Robotic Surgery for Cervical Chordoma Clinical Briefing : 2018.

McCann AC, Berger C, Mahmoud AF, Kuan EC, Malhotra NR, O'Malley BW Jr: Novel approach using transoral robotic surgery for resection of cervical spine chordoma Laryngoscope : 2018.

Sharma N, Piazza M, Marcotte PJ, Welch W, Ozturk AK, Chen HI, Ali ZS, Schuster J, Malhotra NR: Implications of anesthetic approach, spinal vs general, for the treatment of spinal disc herniation J Neurosurg Spine : 2018.

Ali ZS, Ma TS, Ozturk AK, Malhotra NR, Schuster JM, Marcotte PJ, Grady MS, Welch WC: Pre-optimization of spinal surgery patients: Development of a neurosurgical enhanced recovery after surgery (ERAS) protocol Clin Neurol Neurosurg : 2018.

Nayak NR, Piazza M, Milby A, Thawani JP, Smith LJ, Stein SC, Malhotra NR: Surgical Approaches for the Treatment of Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: Results of a Decision Analysis World Neurosurg : 2018.

Pisapia JM, Nayak NR, Salinas RD, Macyszyn L, Lee JY, Lucas TH, Malhotra NR, Isaac Chen H, Schuster JM: Navigated odontoid screw placement using the O-arm: technical note and case series J Neurosurg Spine : 2017.

Tong W, Tian Z, Qin L, Motomi EI, Mauck RL, Smith HE, Smith LJ, Malhotra NR, Heyworth MF, Caldera F, Zhang Y: Cell Therapy for the Degenerating Intervertebral Disc Translational Research 181 : 49-58,2017.

Pisapia JM, Nayak NR, Salinas RD, Macyszyn L, Lee JY, Lucas TH, Malhotra NR, Chen IH, Schuster JM: Navigated Odontoid Screw Placement Using the O-arm: Technical Note and Case Series J Neurosurg Spine 26 (1): 10-18,2017.

Peck SH, McKee KK, Tobias JW, Malhotra NR, Harfe BD, Smith LJ: Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus Sci Rep 7 (1): 10504,2017.

Hitti FL, Hudgins ED, Chen HI, Malhotra NR, Zager EL, Schuster JM: Intraoperative navigation is associated with reduced blood loss during C1-2 posterior cervical fixation World Neurosurg : 2017.

Gullbrand SE, Schaer TP, Agarwal P, Bendigo JR, Dodge G, Chen W, Elliott D, Mauck RL, Smith LJ, Malhotra NR: Translation of an Injectable Triple-Interpenetrating-Network Hydrogel for Intervertebral Disc Regeneration in a Goat Model Acta Biomaterialia 60 : 201-209,2017.

Piazza M, Nayak N, Ali Z, Heuer G, Sanborn M, Stein S, Schuster J, Grady MS, Malhotra NR: Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms World Neurosurgery 103 : 194-200,2017.

Berger I, Nayak N, Schuster JM, Lee JYK, Stein S, Malhotra NR: Microvascular Decompression Versus Stereotactic Radiosurgery for Trigeminal Neuralgia: A Decision Analysis Cureus 9 (1): e1000,2017.

Jiang X, Orton M, Feng R, Hossain E, Malhotra NR, Zager EL, Liu R: Chronic Opioid Usage in Surgical Patients in a Large Academic Center Ann Surg 265 (4): 722-727,2017.

Gullbrand SE, Malhotra NR, Schaer TP, Zawacki Z, Martin JT, Bendigo JR, Milby AH, Dodge GR, Vresilovic EJ, Elliott DM, Mauck RL, Smith LJ: A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration Osteoarthritis Cartilage 25 (1): 146-156,2017.

Nayak NR, Bauman JA, Stein SC, Thawani JP, Malhotra NR: Surgical Approaches for the Treatment of Thoracic Disc Herniation: Results of a Decision Analysis Clin Spine Surg 30 (7): 901-908,2017.

Nayak NR, Richard CE, Martinez-Lage M, Smith H, Malhotra N: Synovial-Type Giant Cell Tumors of the Axial Spine J Neurosurg Sci 61 (1): 106-109,2017.

Baker M, Malhotra NR: En Bloc Spondylectomy and TransOral Robotic Surgery for Cervical Chordoma Clinical Briefing : 2018.

Lorraine L. Janeczko: Statin Shows Promise as Alternative to Surgery for Chronic Brain Bleeds Reuters Health News : 2018.

Ali ZS, Flanders TM, Ozturk A, Malhotra NR, McShane B, Kallan M, Grady MS, Welch WC: Enhanced Recovery After Surgery (ERAS) decreases postoperative opioid use in elective spinal and peripheral nerve surgery – a single institution,one-year study American Academy of Neurological Surgery Meeting : 2018.

Louisa Shepard: Robot Revolution Bellwether Magazine : 2016.

Syre P, Malhotra NR: Chronic Back Pain and Degenerative Disc Disease Clinical Decision Support in Spine Surgery : 2016.

Syre P, Macyszyn, Nyirjesy S, Millhouse PW, Koerner J, Vaccaro AR, Malhotra NR: Advanced Anterior Cervical Foraminotomy Technique Spine Surgery: Tricks of the Trade, 3rd ed. : 2016.

Malhotra NR: Degenerative Disc Disease and Low Back Pain Clinical Decision Support System on Spine Surgery : 2016.

Nayak NR, Stephen JH, Abdullah KG, Stein SC, Malhotra NR: Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study Global Spine J 6 (3): 270-6,2016.

Agarwal P, Burke JF, Abdullah KG, Piazza M, Smith BP, Thawani JP, Malhotra NR: Stab wound to the intramedullary spinal cord: Presurgical and surgical management options for a retained blade to optimize neurological preservation Surgical Neurol Int 7 (Suppl 42): S1096-S1098,2016.

Gorth DJ, Lothstein KE, Chiaro JA, Farrell MJ, Dodge GR, Elliott DM, Malhotra NR, Mauck RL, Smith LJ: Hypoxic Regulation of Functional Extracellular Matrix Elaboration by Nucleus Pulposus Cells in Long-Term Agarose Culture J Orthop Res 33 (5): 747-54,2015.

Showalter BL, Elliott DM, Chen W, Malhotra NR: Evaluation of an In Situ Gelable and Injectable Hydrogel Treatment to Preserve Human Disc Mechanical Function Undergoing Physiologic Cyclic Loading Followed by Hydrated Recovery J Biomech Eng 137 (8): 081008,2015.

Whitmore RG, Curran JN, Ali ZS, Mummaneni PV, Shaffrey CI, Heary RF, Kaiser MG, Asher AL, Malhotra NR, Cheng JS, Hurlbert J, Smith JS, Magge SN, Steinmetz MP, Resnick DK, Ghogawala Z: Predictive Value of 3-Month Lumbar Discectomy Outcomes in the NeuroPoint-SD J Neurosurg Spine 23 (4): 459-66,2015.

Nayak NR, Coats JM, Abdullah KG, Stein SC, Malhotra NR: Tracking Patient-Reported Outcomes in Spinal Disorders Surg Neurol Int 6 (Suppl 19): S490-9,2015.

Smith LJ, Gorth DJ, Showalter BL, Chiaro JA, Beattie EE, Elliott DM, Mauck RL, Chen, Malhotra NR: In Vitro Characterization of a Stem-Cell-Seeded Triple-Interpenetrating-Network Hydrogel for Functional Regeneration of the Nucleus Pulposus Tissue Eng Part A 20 (13-14): 1841-1849,2014.

Ellen Czajkowski: Surviving the Knife. A Surgeon Removes a Knife from a Patients Spinal Cord and the Patient Miraculously Walks Again CBS Eyewitness News : 2014.

Robert Linnehan: Enhanced EMRs May Support Better Treatments and Translational Research Orthopedics / Spine Surgery Today : 2014.

Peck SH, Casal ML, Malhotra NR, Ficicioglu C, Smith LJ: Pathogenesis and Treatment of Spine Disease in the Mucopolysaccharidoses. Featured Cover Article Mol Genet Metab 118 (4): 232-43,2016.

Gorth DG, Martin JT, Dodge GR, Malhotra NR, Elliott DM, Mauck RL, Smith LJ: In Vivo Retention and Bioactivity of IL-1ra Microspheres in the Rat Intervertebral Disc: a Preliminary Investigation Journal of Experimental Orthopaedics 1 (1): 15,2014.

Peck SH, O'Donnell PJ, Kang JL, Malhotra NR, Dodge GR, Pacifici M, Shore EM, Haskins ME, Smith LJ: Delayed Hypertrophic Differentiation of Epiphyseal Chondrocytes Contributes to Failed Secondary Ossification in Mucopolysaccharidosis VII Dogs Mol Genet Metab 116 (3): 195-203,2015.

Lewis DJ, Attiah MA, Malhotra NR, Burnett MG, Stein SC: Anterior Surgical Management of Single-Level Cervical Disc Disease: A Cost-Effectiveness Analysis Spine (Phila Pa 1976) 39 (25): 2084-92,2014.

Malhotra NR: Health-Real Life Drama: Neurosurgeon Saves Spinal Cord and a Patient Walks Again CBS 3 Television News, Sweeps Week : 2014.

Stein SC, Malhotra NR, Burnett MG: Cost-Effectiveness Analysis J Neurosurg Spine 20 (4): 474,2014.

Kelz M, Malhotra NR: The Neurosurgical Operative Experience, a Patients Perspective WHYY “The Pulse”, Host: Maiken Scott : 2014.

Malhotra NR: Improving Surgical Care of the Spinal Disorders: The Osteoporotic Spine J Osteopor Phys Act : 2013.

Schuster JM, Malhotra NR: Posterior Thoracic Instrumentation Youmans Neurological Surgery. Ed 6. : 3061-3068,2011.

Malhotra NR, Kosty J, Sanborn M, Bekisz JM, Mooncai TW, Neustein TM, Ou J, Zhu A, Bernstein A, Stein SC: Optimal Approach to Circumferential Decompression and Reconstruction for Thoracic Spine Metastatic Disease Ann Surg Oncol 21 (9): 2864-2872,2014.

Nestorovski D, Milby AH, Pallavi G, Smith LJ, Smith HE, Malhotra NR: Combined Treatment Approach for Rare Occipito-Cervical Spinal Lesions: Leiomyosarcoma J Spine Neurosurg S1 (003): EPUB only,2013.

Bohman LE, Stephen JH, Ramakrishna R, Schuster JM, Malhotra NR: Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme J Spine Neurosurg S1 (001): EPUB only,2013.

Chen HI, Lang SS, Coyne TM, Malhotra NR, Schuster JM: Intramedullary Spinal Sarcoidosis Masquerading as Cervical Stenosis World Neurosurgery 80 (6): 375-380,2013.

Clement RC, Carr BG, Kallan MJ, Wolff C, Reilly PM, Malhotra NR: Volume-Outcome Relationship in Neurotrauma Care Journal of Neurosurgery 118 (3): 687-93,2013.

Macyszyn L, Lega B, Bohman LE, Latefi A, Smith MJ, Malhotra NR, Welch WC, Grady MS: Implementation of a Departmental Picture Archiving and Communication System: a Productivity and Cost Analysis. Neurosurgery 73 (3): 528-33,2013.

Syre P, Petrov D, Malhotra NR: Management of Upper Cervical Spine Injuries Journal of Neurosurgical Sciences 57 (3): 219-40,2013.

Syre P, Rodriguez-Cruz L, Desai R, Greene KA, Hurst R, Schuster J, Malhotra NR, Marcotte P: Civilian Gunshot Wounds to the Atlantoaxial Spine: a Report of 10 Cases Treated Using a Multidisciplinary Approach Journal of Neurosugery, Spine 19 (6): 759-766,2013.

Ghogawala Z, Shaffrey CI, Asher AL, Heary RF, Logvinenko T, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Abbed KM, Sciubba DM, Resnick DK: The Efficacy of Lumbar Discectomy and Single-Level Fusion for Spondylolisthesis: Results from the NeuroPoint-SD Registry Journal of Neurosurgery, Spine 19 (5): 555-63,2013.

Malhotra NR: Medical Breakthrough: Spinal Surgery Today XM National Radio-ReachMD : 2011.

Mummaneni PV, Whitmore RG, Curran JN, Ziewacz JE, Wadhwa R, Shaffrey CI, Asher AL, Heary RF, Cheng JS, Hurlbert RJ, Douglas AF, Smith JS, Malhotra NR, Dante SJ, Magge SN, Kaiser MG, Abbed KM, Resnick DK, Ghogawala Z: Cost-Effectiveness of Lumbar Discectomy and Single Level Fusion for Spondylolisthesis: Experience with the NeuroPoint SD Registry Neurosurg Focus 36 (6): E3,2014.

Malhotra NR, Lotier L, Becker W, Smith LJ: The Neurosurgery Quality Improvement Initiative Supports Precision Medicine, QI, and Research Epic International Physician Advisory Council : 2014.

Sanborn M, Smith LJ, Malhotra NR: Spinal Cord and Spinal Column The Trauma Manual: Trauma and Acute Care Surgery 4th Edition : 2012.

Clement RC, Carr BG, Kallan MJ, Wolff C, Reilly PM, Malhotra NR: Volume-Outcome Relationship in Neurotrauma Care J Neurosurg : 2012.

Malhotra NR, Whitmore R, Smith LJ, Welch WC, Schuster JM, Marcotte P, Dante S, Arlet V, Brem S, Grady MS: Future Directions in Spine: An Opportunity to Accelerate Quality Improvement J Spine Neurosurg 1 (2): doi: 10.4172.2325-9701.1000e105,2012.

Lang SS, Malhotra NR: Interviewing for Pediatric Fellowship: Finding the Right Work-Work Balance AANS Neurosurgeon 23 (1): 2014.

Sanborn MR, Abdullah K, Smith MJ, Grady MS, Malhotra NR: Improving Core Residency Education: An Argument for Increased Incorporation of Endovascular Surgical Training AANS Neurosurgeon 21 (4): 2012.

Bohman LE, Malhotra NR: The Value of an “Infolded” Fellowship AANS Neurosurgeon 21 (3): 2012.

Macyszyn L, Malhotra NR: Counterpoint: The Intensivist is in Charge AANS Neurosurgeon 21 (3): 2012.

Hwang SW, Malhotra NR, Shaffrey CI, Samdani AF: Intraoperative Neurophysiological Monitoring in Spine Deformity Surgery (Invited Review) Spine Deformity : DOI:/10.1016/j.jspd.2012.05.006,2012.

Malhotra NR, Bhomick D, Hardesty D, Whitfield P: Intramedullary Spinal Cord Tumors: Diagnosis, Treatment and Outcomes (Invited Review) Advances in Clinical Neuroscience and Rehabilitation (ACNR) 10 (4): 21-26,2010.

Lang SS, Chen HI, Koch MJ, Kurash L, McGill-Armento KR, Palella JM, Stein SC, Malhotra NR: Development of an Outpatient Protocol for Lumbar Discectomy World Neurosurg 82 (5): 897-901,2014.

Chiaro JA, O'Donnell P, Shore EM, Malhotra NR, Ponder KP, Haskins ME, Smith LJ: Effects of Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Disease in Mucopolysaccharidosis I Dogs J Bone Miner Res 29 (12): 2610-2617,2014.

Showalter BL, Malhotra NR, Vresilovic EJ, Elliott DM: Nucleotomy Reduces the Effects of Cyclic Compressive Loading with Unloaded Recovery on Human Intervertebral Discs J Biomech 47 (11): 2633-2640,2014.

Ali Z, Barkley A, Malhotra NR: Acute Spinal Subdural Hematoma Subsequent To Posterior Lumbar Fusion J Osteopor Phys 1 (1): EPUB only,2013.

Lang SS, Schuster JM, Smith LJ, Dwyer-Joyce L, Welch W, Marcotte P, Winkelstein B, Malhotra NR: Hemorrhage into Synovial Cysts as a Cause of Acute Radicular Symptoms. A report of 7 Cases and Review of Literature. J Spine Neurosurg 2 (1): EPUB only,2012.

Malhotra NR, Han WM, Beckstein J, Cloyd J, Chen W, Elliott DM: An Injectable Nucleus Pulposus Implant Restores Compressive Range of Motion in the Ovine Disc Spine 37 (18): E1099-105,2012.

Sanborn MR, Thawani JP, Whitmore RG, Shmulevich M, Hardy B, Benedetto C, Malhotra NR, Marcotte P, Welch W, Dante S, Stein SC: Cost-Effectiveness of Confirmatory Techniques for the Placement of Lumbar Pedicle Screws. Neurosurgical Focus 33 (1): E12,2012.

Lega BC, Danish SF, Malhotra NR, Sonnad SS, Stein SC: Choosing the Best Operation for Chronic Subdural Hematoma: a Decision Analysis. Journal of Neurosurgery 113 (3): 615-21,2010.

Malhotra NR, Shaffrey CI: Intraoperative Electrophysiological Monitoring in Spine Surgery (Invited Review) Spine 35 (25): 2167-79,2010.

O'Connell Grace D, Malhotra Neil R, Vresilovic Edward J, Elliott Dawn M: The Effect of Nucleotomy and the Dependence of Degeneration of Human Intervertebral Disc Strain in Axial Compression. Spine 36 (21): 1765-1771,2011.

Wendell LC, Khan A, Raser J, Lang SS, Malhotra NR, Kofke WA, LeRoux P, Park S, Levine JM.: Successful Management of Refractory Intracranial Hypertension from Acute Hyperammonemic Encephalopathy in a Woman with Ornithine Transcarbamylase Deficiency Neurocrit Care 13 (1): 113-117,2010.

Hunt J, Fang K, Snyder A, Malhotra NR, Gaston BM: Ammonia Depletion in Asthma Diminishes Buffering of Endogenous Airway Acid Journal of Allergy and Clinical Immunology 105 (1): S193,2000.

Malhotra NR, Cloyd J, Beckstein J, Chen W, Elliott DM: An In-Situ Polymerizing Hydrogel to Mimic Nucleus Pulposus Ex Vivo and In Vitro. (Society Scientific Paper of the Year Award) Pennsylvania Neurosurgical Society : 2008.

Plaha P, Malhotra NR, Heuer G, Whitfield P: Management of Chronic Subdural Hematoma Advances in Clinical Neuroscience and Rehabilitation (ACNR) 8 (5): 12-15,2008.

Cloyd JM, Malhotra NR, Weng L, Chen W, Mauck RL, Elliott DM: Material Properties in Unconfined Compression of Human Nucleus Pulposus, Injectable Hyaluronic Acid-Based Hydrogels and Tissue Engineering Scaffolds. European Spine Journal 16 (11): 1892-8,2007.

Espinoza Orías AA, Malhotra NR, Elliott DM: Rat Disc Torsional Mechanics: Effect of Lumbar and Caudal Levels and Axial Compression Load The Spine Journal : Journal of the North American Spine Society 9 (3): 204-9,2009.

Lega B, Malhotra NR, Danish S, Stein S: The Best Operation for Chronic Subdural Hematoma: A Decision Analysis (Best Scientific Poster Award / 1st Place) Pennsylvania Neurosurgical Society : 2008.

Malhotra NR, Grady MS: Anterior Cervical Foraminotomy Technique Spine Surgery: Tricks of the Trade, 2nd ed. : 54-56,2009.

Thomas P, Malhotra NR, Grady MS: Injury to the Spinal Cord Trauma: Contemporary Principles and Therapy : 289-297,2008.

Malhotra NR, Thomas P, Grady MS: Injury to the Spine Trauma: Contemporary Principles and Therapy : 297-304,2008.

Malhotra NR, Whitfield P: Review of “The Legacy of Harvey Cushing” Advances in Clinical Neuroscience and Rehabilitation (ACNR) 8 (3): 2008.

Hunt JF, Fang K, Malik R, Snyder A, Malhotra NR, Platts-Mills TA, Gaston B: Endogenous Airway Acidification. Implications for Asthma Pathophysiology Am J Respir Crit Care Med 161 (3 part 1): 694-9,2000.

Hunt JF, Erwin E, Palmer L, Vaughan J, Malhotra NR, Platts-Mills TA, Gaston B: Expression and Activity of pH-Regulatory Glutaminase in the Human Airway Epithelium Am J Respir Crit Care Med 165 (1): 101-7,2002.

Gaston B, Ratjen F, Vaughan JW, Malhotra NR, Canady RG, Snyder AH, Hunt JF, Gaertig S, Goldberg JB: Nitrogen Redox Balance in the Cystic Fibrosis Airway: Effects of Antipseudomonal Therapy Am J Respir Crit Care Med 165 (3): 387-90,2002.

Boockvar JA, Stiefel M, Malhotra NR, Dolinskas C, Dwyer-Joyce C, LeRoux PD: Dural Cavernous Angioma of the Posterior Sagittal Sinus Surg Neurol 63 (2): 178-181,2005.

Chen HI, Malhotra NR, Oddo M, Heuer GG, Levine JM, LeRoux PD: Barbiturate Infusion for Intractable Intracranial Hypertension and its Effect on Brain Oxygenation Neurosurgery 63 (5): 880-6,2008.

Academic Contact Info

Vice Chairman for Operations

Associate Professor and Program Director, Neurological Surgery
Associate Professor, Orthopedic Surgery
Director, EpiLog Quality Improvement Initiative
Co-Director, Restorative Spinal Research Laboratory

3 Silverstein
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-3487
Patient appointments: 800-789-7366 (PENN)

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