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Neil R. Malhotra, MD

Neil R. Malhotra, MD Surgeon

Co-Director, Translational Spine Research Lab Director, Neurosurgery Quality Improvement Initiative Vice Chairman for Operations, Department of Neurosurgery Assistant Professor of Neurosurgery at the Hospital of the University of Pennsylvania Assistant Professor of Orthopaedic Surgery

Languages spoken:

  • Spanish

Dr. Malhotra is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties

Specialty:

  • Neurosurgery

Programs & Centers:

Board Certification:

  • Neurological Surgery, 2015

Clinical Expertise:

  • Astrocytoma
  • Back Surgery
  • Bone Lesions
  • Brain Cancer
  • Brain Metastasis
  • Brain Tumors
  • Cervical Degenerative Disc Disease
  • Cervical Myelopathy
  • Cervical Spine Surgery
  • Herniated Disc Surgery
  • Kyphosis
  • Lumbar Disc Surgery
  • Meningioma
  • Micro Endoscopic Herniated Disc Surgery
  • Spinal Compression
  • Spinal Degenerative Disease
  • Spinal Disc Degeneration
  • Spinal Fusion Surgery
  • Spinal Stenosis
  • Spinal Tumor
  • Spine - Ankylosing Spondylitis
  • Spine Biopsy
  • Spine Cancer
  • Spine Disease
  • Spine Disorders
  • Spine Fracture
  • Spine Instrumentation
  • Spine Microsurgery
  • Spine Stabilization
  • Spine Surgery
  • Spine Trauma
  • Spondylosis
  • Traumatic Brain Injury (TBI) Surgery

Description of Clinical Expertise

Dr. Malhotra is the Vice Chairman for Operations and Associate Program Director of the Department of Neurological Surgery at the University of Pennsylvania. He oversees strategic initiatives to enhance the quality of patient care. Dr. Malhotra has published more than 50 articles and book chapters related to his clinical and research work. Dr. Malhotra's work, along with that of his partners, has led to the University of Pennsylvania being the top rated neurosurgical department in the region for every year that the rankings have been completed. Further, the department is consistently ranked amongst the top 10 in the United States.

From a clinical standpoint, Dr. Malhotra provides expertise in the care of brain and spine neurological disorders. His clinical goals focus on optimizing quality of life as well as life expectancy for disorders of the nervous system. He takes particular interest in the development of advanced approaches to brain and spinal lesion treatment (such as meningioma) and spinal column reconstruction in addition to the treatment of cervical and lumbar disc herniation and spondylolisthesis. He is the first to have performed Endoscopic and Exoscopic Spinal Fusion Surgery (a less invasive form of spinal nerve decompression and fusion).

As director and creator of the Neurosurgery Quality Improvement Initiative Dr. Malhotra has developed a software system within the electronic medical record system to enhance disease management and predict response to therapy. His system, the EpiLog project, has completed beta testing and is now in use to enhance all patient care.

In 2011, Dr. Malhotra developed an outreach program in order to enhance and facilitate patient care. To support this program Dr. Malhotra sees patients in King of Prussia and Chestnut Hill, in addition to his primary site at the University of Pennsylvania.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School:
Residency: Hospital of the University of Pennsylvania

Memberships

American Association of Neurological Surgeons, National AO Spine Educational Association, International Congress of Neurological Surgeons, National National Neurosurgery Quality Outcomes Database, National North American Spine Society, International Pennsylvania Neurosurgical Society, Local Section for the Spine and Peripheral Nerves, American Association of Neurological Surgeons/Congress of Neurological Surgeons, National Section on History of Neurological Surgery, American Association of Neurological Surgeons, National

Hospital Affiliation

Dr. Malhotra is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

As Co-Director of the Translational Spinal Research Laboratory (TSRL), Dr. Malhotra's primary research interests focus on restorative approaches to treat disc degeneration. His novel approaches have led to multiple awards and research grants. Through his work, Dr. Malhotra hopes to reduce the need for spinal surgery and offer better treatments for disc degeneration. His interests focus on tissue engineering in order to develop treatments to restore native tissue mechanics of the spine while also delivering therapeutic agents and supporting tissue regeneration.

Selected Publications:

Peck SH, McKee KK, Tobias JW, Malhotra NR, Harfe BD: Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus Sci Rep 7 (1): 10504,2017.

Hitti FL, Hudgins ED, Chen HI, Malhotra NR, Zager EL: Intraoperative navigation is associated with reduced blood loss during C1-2 posterior cervical fixation World Neurosurg : 2017.

Gullbrand SE, Schaer TP, Agarwal P, Bendigo JR, Dodge G, Chen W, Elliott D, Mauck RL, Smith LJ: Translation of an Injectable Triple-Interpenetrating-Network Hydrogel for Intervertebral Disc Regeneration in a Goat Model Acta Biomaterialia 60 : 201-209,2017.

Piazza M, Nayak N, Ali Z, Heuer G, Sanborn M, Stein S, Schuster J, Grady MS: Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms World Neurosurgery 103 : 194-200,2017.

Berger I, Nayak N, Schuster JM, Lee JYK, Stein S: Microvascular Decompression Versus Stereotactic Radiosurgery for Trigeminal Neuralgia: A Decision Analysis Cureus 9 (1): e1000,2017.

Nayak NR: Quality-of-Life in Patients Undergoing Spine Surgery: Systematic Review and Meta-Analysis Global Spine J : Accepted 2017.

Jiang X, Orton M, Feng R, Hossain E, Malhotra NR, Zager EL: Chronic Opioid Usage in Surgical Patients in a Large Academic Center Ann Surg 265 (4): 722-727,2017.

Gullbrand SE, Malhotra NR, Schaer TP, Zawacki Z, Martin JT, Bendigo JR, Milby AH, Dodge GR, Vresilovic EJ, Elliott DM, Mauck RL: A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration Osteoarthritis Cartilage 25 (1): 146-156,2017.

Nayak NR, Richard CE, Martinez-Lage M, Smith H: Synovial-Type Giant Cell Tumors of the Axial Spine J Neurosurg Sci 61 (1): 106-109,2017.

Gorth DJ, Lothstein KE, Chiaro JA, Farrell MJ, Dodge GR, Elliott DM, Malhotra NR, Mauck RL: Hypoxic Regulation of Functional Extracellular Matrix Elaboration by Nucleus Pulposus Cells in Long-Term Agarose Culture J Orthop Res 33 (5): 747-54,2015.

Showalter BL, Elliott DM, Chen W: Evaluation of an In Situ Gelable and Injectable Hydrogel Treatment to Preserve Human Disc Mechanical Function Undergoing Physiologic Cyclic Loading Followed by Hydrated Recovery J Biomech Eng 137 (8): 081008,2015.

Whitmore RG, Curran JN, Ali ZS, Mummaneni PV, Shaffrey CI, Heary RF, Kaiser MG, Asher AL, Malhotra NR, Cheng JS, Hurlbert J, Smith JS, Magge SN, Steinmetz MP, Resnick DK: Predictive Value of 3-Month Lumbar Discectomy Outcomes in the NeuroPoint-SD J Neurosurg Spine 23 (4): 459-66,2015.

Peck SH, O'Donnell PJ, Kang JL, Malhotra NR, Dodge GR, Pacifici M, Shore EM, Haskins ME: Delayed Hypertrophic Differentiation of Epiphyseal Chondrocytes Contributes to Failed Secondary Ossification in Mucopolysaccharidosis VII Dogs Mol Genet Metab 116 (3): 195-203,2015.

Nayak NR, Coats JM, Abdullah KG, Stein SC: Tracking Patient-Reported Outcomes in Spinal Disorders Surg Neurol Int 6 (Suppl 19): S490-9,2015.

Lewis DJ, Attiah MA, Malhotra NR, Burnett MG: Anterior Surgical Management of Single-Level Cervical Disc Disease: A Cost-Effectiveness Analysis Spine (Phila Pa 1976) 39 (25): 2084-92,2014.

Showalter BL, Elliott DM, Chen W, Smith LJ: Hydrogel Implant Stabilizes Human Disc Mechanics Under Physiologic Cyclic Loading Following Nucleotomy American Association of Neurological Surgeons : 2014.

Showalter BL, Milby AH, Haughan J, Mauck RL, Elliott DM, Malhotra NR, Schaer TP: Percutaneous Delivery of Chondroitinase ABC for Initiation of Disc Degeneration in a Goat Model American Association of Neurological Surgeons : 2014.

Smith LJ, Chiaro JA, O'Donnell P, Ponder KP, Malhotra NR, Elliott DM, Shore EM: Effects of Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Disease in Mucopolysaccharidosis I Dogs Lysosomal Disease Network's World Symposium : 2014.

Chiaro JA, O'Donnell P, Malhotra NR, Ponder KP, Haskins ME: Effects of Combined Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Intervertebral Disc Disease in Mucopolysaccharidosis I Orthopedic Research Society : 2014.

Smith LJ, Chiaro JA, McKee KK, Mauck RL, Malhotra NR: Deep Sequencing of Notochord-Derived Cells During Embryonic Formation of the Nucleus Pulposus Orthopedic Research Society : 2014.

Milby AH, Showalter BL, Haughan J, Mauck RL, Elliott DM, Malhotra NR, Schaer TP: Percutaneous Delivery of Chondroitinase ABC Induces Moderate Disc Degeneration in a Goat Model Orthopedic Research Society : 2014.

Showalter BL, Amin DB, Marcozzi AN, Elliott DM: Injectable Hydrogel Treatment Stabilizes Human Disc Mechanical Function Under Physiologic Cyclic Loading Orthopedic Research Society : 2014.

Malhotra NR, Chiaro JA, O’Donnell P, Ponder KP, Haskins ME: Statins with Enzyme Replacement Therapy Treats Intervertebral Disc Disease in Mucopolysaccharidosis I Dogs American Association of Neurological Surgeons : 2014.

Lewis DJ, Malhotra NR, Burnett MG, Attiah MA, Bailey RL: Comparative Effectiveness of Anterior Cervical Discectomy (With and Without Fusion) and Arthroplasty in Single-Level Disc Disease: A Decision Analysis American Association of Neurological Surgeons : 2014.

Milby AH, Showalter BL, Haughan J, Mauck RL, Elliott DM, Malhotra NR, Schaer TP: Percutaneous Delivery of Chondroitinase ABC Induces Moderate Disc Degeneration in a Goat Model McKay Orthopedics Research Symposium : 2014.

Smith LJ, Chiaro JC, O'Donnell P, Ponder KP, Malhotra NR, Elliott DM, Shore EM: Leveraging Simvastatin Treatment Along with Neonatal Enzyme Replacement Therapy to Improve Cervical Spine Disease in Mucopolysaccharidosis I Dogs Mckay Orthopedics Research Symposium : 2014.

Showalter BL, Elliott DM: Injectable Hydrogel Treatment Stabilizes Human Disc Range of Motion Under Physiologic Cyclic Loading (Special Oral Poster Presentation) The International Society for the Study of the Lumbar Spine (ISSLS) : 2014.

Malhotra NR, Lotier L, Becker W: The Neurosurgery Quality Improvement Initiative Supports Precision Medicine, QI, and Research Epic International Physician Advisory Council : 2014.

Malhotra NR, Schuster JM: Best of Both Worlds Suburban Life, Main Line, Delaware County magazine. Author: Hengel A 5 (10): 2014.

Health-Real Life Drama: Neurosurgeon Saves Spinal Cord and a Patient Walks Again CBS 3 Television News, Sweeps Week : 2014.

Stein SC, Malhotra NR: Cost-Effectiveness Analysis J Neurosurg Spine 20 (4): 474,2014.

Kelz M: The Neurosurgical Operative Experience, a Patients Perspective WHYY “The Pulse”, Host: Maiken Scott : 2014.

Lang SS: Interviewing for Pediatric Fellowship: Finding the Right Work-Work Balance AANS Neurosurgeon 23 (1): 2014.

Lang SS, Chen HI, Koch MJ, Kurash L, McGill-Armento KR, Palella JM, Stein SC: Development of an Outpatient Protocol for Lumbar Discectomy World Neurosurg 82 (5): 897-901,2014.

Chiaro JA, O'Donnell P, Shore EM, Malhotra NR, Ponder KP, Haskins ME: Effects of Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Disease in Mucopolysaccharidosis I Dogs J Bone Miner Res 29 (12): 2610-2617,2014.

Showalter BL, Malhotra NR, Vresilovic EJ: Nucleotomy Reduces the Effects of Cyclic Compressive Loading with Unloaded Recovery on Human Intervertebral Discs J Biomech 47 (11): 2633-2640,2014.

Smith LJ, Gorth DJ, Showalter BL, Chiaro JA, Beattie EE, Elliott DM, Mauck RL, Chen: In Vitro Characterization of a Stem-Cell-Seeded Triple-Interpenetrating-Network Hydrogel for Functional Regeneration of the Nucleus Pulposus Tissue Eng Part A 20 (13-14): 1841-1849,2014.

Malhotra NR, Kosty J, Sanborn M, Bekisz JM, Mooncai TW, Neustein TM, Ou J, Zhu A, Bernstein A: Optimal Approach to Circumferential Decompression and Reconstruction for Thoracic Spine Metastatic Disease Ann Surg Oncol 21 (9): 2864-2872,2014.

Lega B, Malhotra NR, Danish S: The Best Operation for Chronic Subdural Hematoma: A Decision Analysis (Best Scientific Poster Award / 1st Place) Pennsylvania Neurosurgical Society : 2008.

Gorth, DJ, Elliott, DM, Mauck RL, Chen, W, Smith, LJ: Mechanical Properties and Cyto-Compatibility of an Injectable Hydrogel Implant for Nucleus Pulposus Repair Orthopedic Research Society : 2013.

Gorth DJ, Martin JT, Dodge GR, Hebela N, Malhotra NR, Mauck RL, Elliott DM: In Vivo Delivery of IL-1ra from PLGA Microspheres Prevents IL-1b Induced Glycosaminoglycan Loss in the Rat Caudal Intervertebral Disc ASME Global Conference for Nano Engineering for Medicine and Biology (NEMB) : 2013.

Sanborn MR, Malhotra NR, Carr B, Kalian M, Grady MS: Endovascular Interventions and Duty Hour Restrictions Drastically Reduce Aneurysm Clip Ligation Experience by US Trainees SNIS International Endovascular Stroke Conference and Joint Cerebrovascular Section : 2013.

Gorth DJ, Martin JT, Elliott DM, Dodge GR, Malhotra NR, Mauck RL: In Vivo Retention and Bioactivity of IL-1RA Microspheres in the Rat Caudal Intervertebral Disc International Society for the Study of the Lumbar Spine : 2013.

Shaffrey CI, Smith JS, Mummaneni PV, Ziewacz J, Cheng JS, Whitmore RG, Ghogawala Z, Malhotra NR, Magge S, Asher AL, Resnick D, Knightly J, Kaiser M, Abbed K: Establishing the Efficacy of Lumbar Discectomy and Single Level Fusion for Spondylolisthesis -Experience with the AANS’ NeuroPoint SD Registry International Meeting on Advanced Spine Techniques (IMAST) : 2013.

Smith LJ, Chiaro JC, Ponder KP, Malhotra NR, Elliott DM, Shore EM: Neonatal Enzyme Replacement Therapy Attenuates Vertebral Bone Disease in the Cervical Spines of Mucopolysaccharidosis I Dogs (Young Investigator Award winner) American Society for Bone and Mineral Research : 2013.

Smith LJ, Chiaro JA, McKee KK, Mauck RL, Malhotra NR: Deep Sequencing of Notochord-Derived Cells During Embryonic Formation of the Nucleus Pulposus: Preliminary Findings International Philadelphia Spine Research Symposium : 2013.

Chiaro JC, O'Donnell P, Shore EM, Malhotra NR, Elliott DM Ponder KP, Haskins ME: Neonatal Enzyme Replacement Therapy Attenuates Cervical Spine Bone and Disc Disease in Mucopolysaccharidosis I Dogs International Philadelphia Spine Research Symposium : 2013.

Showalter BL, Amin DB, Marcozzi AN, Elliott DM: Injectable Hydrogel Treatment Stabilizes Human Disc Mechanical Function Under Physiologic Cyclic Loading Penn Center for Musculoskeletal Disorders Symposium : 2013.

Showalter BL, Amin DB, Marcozzi AN, Elliott DM: Hydrogel Implant Restores Human Disc Mechanics Under Physiologic Cyclic Loading Following Nucleotomy International Philadelphia Spine Research Society : 2013.

Milby AH, Attiah M, Massey P, Malhotra NR: Surgical Management of Cervical Myelopathy Due to Ossification of the Posterior Longitudinal Ligament: a Decision Analysis Cervical Spine Research Society : 2013.

New Options for Brain and Spinal Conditions Chestnut Hill Local : 2013.

The Effect of July Admission on Inpatient Outcomes Following Spinal Surgery Medscape Neurology : 2013.

Improving Surgical Care of the Spinal Disorders: The Osteoporotic Spine J Osteopor Phys Act : 2013.

Nestorovski D, Milby AH, Pallavi G, Smith LJ, Smith HE: Combined Treatment Approach for Rare Occipito-Cervical Spinal Lesions: Leiomyosarcoma J Spine Neurosurg S1 (003): EPUB only,2013.

Bohman LE, Stephen JH, Ramakrishna R, Schuster JM: Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme J Spine Neurosurg S1 (001): EPUB only,2013.

Ali Z, Barkley A: Acute Spinal Subdural Hematoma Subsequent To Posterior Lumbar Fusion J Osteopor Phys 1 (1): EPUB only,2013.

Chen HI, Lang SS, Coyne TM, Malhotra NR: Intramedullary Spinal Sarcoidosis Masquerading as Cervical Stenosis World Neurosurgery 80 (6): 375-380,2013.

Clement RC, Carr BG, Kallan MJ, Wolff C, Reilly PM: Volume-Outcome Relationship in Neurotrauma Care Journal of Neurosurgery 118 (3): 687-93,2013.

Macyszyn L, Lega B, Bohman LE, Latefi A, Smith MJ, Malhotra NR, Welch WC: Implementation of a Departmental Picture Archiving and Communication System: a Productivity and Cost Analysis. Neurosurgery 73 (3): 528-33,2013.

Syre P, Petrov D: Management of Upper Cervical Spine Injuries (Invited Review) Journal of Neurosurgical Sciences 57 (3): 219-40,2013.

Syre P, Rodriguez-Cruz L, Desai R, Greene KA, Hurst R, Schuster J, Malhotra NR: Civilian Gunshot Wounds to the Atlantoaxial Spine: a Report of 10 Cases Treated Using a Multidisciplinary Approach Journal of Neurosugery, Spine 19 (6): 759-766,2013.

Ghogawala Z, Shaffrey CI, Asher AL, Heary RF, Logvinenko T, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Abbed KM, Sciubba DM: The Efficacy of Lumbar Discectomy and Single-Level Fusion for Spondylolisthesis: Results from the NeuroPoint-SD Registry Journal of Neurosurgery, Spine 19 (5): 555-63,2013.

Ghogawala Z, Shaffrey CI, Asher AL, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Heary RF, Abbed KM, Sciubba DM: The Design and Development of the Neuropoint SD Spine Registry for Lumbar Discectomy and Single Level Fusion for Spondylolisthesis AANS/CNS Section on Disorders of the Spine and Peripheral Nerves : 2012.

Ghogawala Z, Shaffrey CI, Asher AL, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Heary RF, Abbed KM, Sciubba DM: The Efficacy of Lumbar Discectomy and Single Level Fusion for Spondylolisthesis: Neuropoint SD Registry Results American Association of Neurological Surgeons : 2012.

Clement RC, Kallan MJ, Carr BG, Reilly PM: Neurotrauma: Who Should Treat and Who Should Transfer? American Association of Neurological Surgeons : 2012.

McGill-Aremento K, Palella JM, Pasao NP, Gardiner D, Chen HI, Rupich K, Maloney E: Lumbar Discectomy Surgery as an Outpatient Procedure: A Paradigm Shift American Association of Nurse Practitioners : 2012.

Showalter BL, MacLean IS, Elliott DM: Nucleotomy Alters Mechanical Function Following Cyclic Loading and Unloaded Recovery of Human Discs American Society of Mechanical Engineering : 2012.

Koch M, Chen I, Lang SS, Mcgill-Armento K, Palella J, Pasao N: Initial Experience with Outpatient One-Level Lumbar Discectomy Pennsylvania Neurosurgical Society : 2012.

Sanborn MR, Pisapia J, Carr M, Stein SC, Grady MS: Resident Training: The Impact of Duty Hours and the Rise of Endovascular Neurosurgery on Resident Operative Experience Pennsylvania Neurosurgical Society : 2012.

Smith LJ, Gorth DJ, Chiaro JA, Martin JT, Dodge GR, Malhotra NR, Hebela NM, Mauck RL: Targeting Inflammation in Intervertebral Disc Degeneration International Symposium on Nanomedicine in Drug Delivery and Cancer Diagnosis : 2012.

Showalter BL, Malhotra NR: Nucleotomy Alters Mechanical Response of Human Discs Undergoing Cyclic Loading and Hydrated Recovery Philadelphia Spine Symposium : 2012.

Gorth DJ, Elliott DM, Mauck RL, Chen W, Smith LJ: Mechanical Properties and Cyto-Compatibility of an Injectable Hydrogel Implant for Nucleus Pulposus Repair Philadelphia Spine Symposium : 2012.

Sanborn M, Smith LJ: Spinal Cord and Spinal Column The Trauma Manual: Trauma and Acute Care Surgery 4th Edition : 2012.

Clement RC, Carr BG, Kallan MJ, Wolff C, Reilly PM: Volume-Outcome Relationship in Neurotrauma Care J Neurosurg : 2012.

Malhotra NR, Whitmore R, Smith LJ, Welch WC, Schuster JM, Marcotte P, Dante S, Arlet V, Brem S: Future Directions in Spine: An Opportunity to Accelerate Quality Improvement J Spine Neurosurg 1 (2): doi: 10.4172.2325-9701.1000e105,2012.

Sanborn MR, Abdullah K, Smith MJ, Grady MS: Improving Core Residency Education: An Argument for Increased Incorporation of Endovascular Surgical Training AANS Neurosurgeon 21 (4): 2012.

Bohman LE: The Value of an “Infolded” Fellowship AANS Neurosurgeon 21 (3): 2012.

Macyszyn L: Counterpoint: The Intensivist is in Charge AANS Neurosurgeon 21 (3): 2012.

Hwang SW, Malhotra NR, Shaffrey CI: Intraoperative Neurophysiological Monitoring in Spine Deformity Surgery (Invited Review) Spine Deformity : DOI:/10.1016/j.jspd.2012.05.006,2012.

Lang SS, Schuster JM, Smith LJ, Dwyer-Joyce L, Welch W, Marcotte P, Winkelstein B: Hemorrhage into Synovial Cysts as a Cause of Acute Radicular Symptoms. A report of 7 Cases and Review of Literature. J Spine Neurosurg 2 (1): EPUB only,2012.

Malhotra NR, Han WM, Beckstein J, Cloyd J, Chen W: An Injectable Nucleus Pulposus Implant Restores Compressive Range of Motion in the Ovine Disc Spine 37 (18): E1099-105,2012.

Sanborn MR, Thawani JP, Whitmore RG, Shmulevich M, Hardy B, Benedetto C, Malhotra NR, Marcotte P, Welch W, Dante S: Cost-Effectiveness of Confirmatory Techniques for the Placement of Lumbar Pedicle Screws. Neurosurgical Focus 33 (1): E12,2012.

Malhotra NR, Han W, Beckstein J, Cloyd J, Chen W: An Injectable Nucleus Pulposus Implant to Restore Spinal Range of Motion in Compression Orthopeadic Research Society : 2011.

Gerasimowicz KM, Yoder JH, Tustison NJ, Song G, O’Connell G, Malhotra NR, Vresilovic EJ, Wright AC, Gee JC: Optimization of Image Registration and Application to Human Disc Mechanics with Nucleotomy Northeast Bioengineering : 2011.

Schuster JM: Posterior Thoracic Instrumentation Youmans Neurological Surgery. Ed 6. : 3061-3068,2011.

Costotransversectomy and Corpectomy for Solitary Spinal Metastases Pennsylvania Neurosurgical Society Clinical Education and Guidelines : 2011.

Medical Breakthrough: Spinal Surgery Today XM National Radio-ReachMD : 2011.

O'Connell Grace D, Malhotra Neil R, Vresilovic Edward J: The Effect of Nucleotomy and the Dependence of Degeneration of Human Intervertebral Disc Strain in Axial Compression. Spine 36 (21): 1765-1771,2011.

Welch WC, Tambi V, Sestokas AK, Dante SJ, Malhotra NR: Neurophysiological Detection and Reversal of Evolving Ishemic Injury During da Vinci Robot Assisted Anterior Lumbar Spinal Surgery BIT World Congress : 2010.

Malhotra NR, Bhomick D, Hardesty D: Intramedullary Spinal Cord Tumors: Diagnosis, Treatment and Outcomes (Invited Review) Advances in Clinical Neuroscience and Rehabilitation (ACNR) 10 (4): 21-26,2010.

Lega BC, Danish SF, Malhotra NR, Sonnad SS: Choosing the Best Operation for Chronic Subdural Hematoma: a Decision Analysis. Journal of Neurosurgery 113 (3): 615-21,2010.

Malhotra NR: Intraoperative Electrophysiological Monitoring in Spine Surgery (Invited Review) Spine 35 (25): 2167-79,2010.

Wendell LC, Khan A, Raser J, Lang SS, Malhotra NR, Kofke WA, LeRoux P, Park S: Successful Management of Refractory Intracranial Hypertension from Acute Hyperammonemic Encephalopathy in a Woman with Ornithine Transcarbamylase Deficiency Neurocrit Care 13 (1): 113-117,2010.

Heuer GG, Grant R, Shiveindra J, Malhotra NR, Whitmore R, Storm P: Expandable Cages for the Treatment of High Thoracic Lesions Pennsylvania Neurosurgical Society : 2008.

Malhotra NR, Cloyd J, Beckstein J, Chen W: An In-Situ Polymerizing Hydrogel to Mimic Nucleus Pulposus Ex Vivo and In Vitro. (Society Scientific Paper of the Year Award) Pennsylvania Neurosurgical Society : 2008.

Heuer GG, Grant RA, Jeyamohan S, Malhotra NR, Whitmore RG, Storm PB: Treatment of High Thoracic Lesions via an Entirely Posterior Approach with Placement of Expandable Cages Congress of Neurological Surgeons : 2008.

O’Connell GD, Vresilovic EJ, Malhotra NR: Discectomy Increases Internal Strains of the Disc Under Physiological Loads The International Society for the Study of the Lumbar Spine (ISSLS) : 2009.

Plaha P, Malhotra NR, Heuer G: Management of Chronic Subdural Hematoma (Invited Review) Advances in Clinical Neuroscience and Rehabilitation (ACNR) 8 (5): 12-15,2008.

Espinoza Orías AA, Malhotra NR: Rat Disc Torsional Mechanics: Effect of Lumbar and Caudal Levels and Axial Compression Load The Spine Journal : Journal of the North American Spine Society 9 (3): 204-9,2009.

Malhotra NR: Anterior Cervical Foraminotomy Technique Spine Surgery: Tricks of the Trade, 2nd ed. : 54-56,2009.

Thomas P, Malhotra NR: Injury to the Spinal Cord Trauma: Contemporary Principles and Therapy : 289-297,2008.

Malhotra NR, Thomas P: Injury to the Spine Trauma: Contemporary Principles and Therapy : 297-304,2008.

Malhotra NR: Review of “The Legacy of Harvey Cushing” Advances in Clinical Neuroscience and Rehabilitation (ACNR) 8 (3): 2008.

Chen HI, Malhotra NR, Oddo M, Heuer GG, Levine JM: Barbiturate Infusion for Intractable Intracranial Hypertension and its Effect on Brain Oxygenation Neurosurgery 63 (5): 880-6,2008.

Malhotra NR, Cloyd J, Beckstein J, Chen W: Reversing Disc Degeneration via Restoration of Nucleus Pulposus Functional Mechanics Pan Philadelphia Neuroscience Meeting : 2007.

Cloyd J, Malhotra NR, Weng L, Chen W, Mauck RL: Defining Unconfined Compression Modulus and Poisson’s Ratio for Human Nucleus Pulposus & Potential Nucleus Replacement Materials Orthopedic Research Society : 2007.

Malhotra NR, Cloyd J, Beckstein J, Chen W: A Novel Injectable Nucleus Pulposus Implant Restores Range of Motion The Spine Arthroplasty Society : 2007.

Malhotra NR, Beckstein J, Cloyd J, Chen W: Restoration of Nucleus Pulposus Functional Mechanics via a Novel Injectable Implant International Society for the Study off The Lumbar Spine (ISSLS) : 2007.

Heuer GG, Jeyamohan S, Malhotra NR, Zaghloul KA, Magge SN: Use of Expandable Cages in Pediatric Lumbar Burst Fractures Pennsylvania Neurosurgical Society : 2007.

Malhotra NR, Beckstein J, Cloyd J, Chen W: An In-Situ Polymerizing Hydrogel to Mimic Nucleus Pulposus Ex Vivo and In Vitro International Meeting on Advanced Spinal Techniques (IMAST) : 2007.

Heuer GG, Magge SN, Jeyamohan S, Malhotra NR, Zaghloul KA: Use of Expandable Cages in Pediatric Lumbar Burst Fractures Congress of Neurological Surgeons : 2007.

Malhotra NR, Beckstein J, Cloyd J, Chen W: Criteria and Design Approach for Tissue Engineered Nucleus Pulposus Implants for Degenerative Disc Disease Congress of Neurological Surgeons : 2007.

Cloyd JM, Malhotra NR, Weng L, Chen W, Mauck RL: Material Properties in Unconfined Compression of Human Nucleus Pulposus, Injectable Hyaluronic Acid-Based Hydrogels and Tissue Engineering Scaffolds. European Spine Journal 16 (11): 1892-8,2007.

Malhotra NR, Huang J: Hemorrhage Into Synovial Cysts as a Cause of Acute Radicular Symptoms AANS/CNS Section on Disorders of the Spine and Peripheral Nerves : 2006.

Ramakrishna R, Malhotra NR, Burnett M, Maloney E: Survival in Patients with Glioblastoma Multiforme as a Function of Post-Operative Ambulation Status American Association of Neurological Surgeons : 2006.

Chen I, Malhotra NR, Levine J: The Effect of Barbiturate Infusion on Cerebral Oxygenation Pennsylvania Neurosurgical Society : 2006.

Malhotra NR, Cloyd J, Beckstein J, Chen W: Injectable Hydrogels to Support Nucleus Pulposus Function: Implant Design Pennsylvania Neurosurgical Society : 2006.

Mummaneni PV, Whitmore RG, Curran JN, Ziewacz JE, Wadhwa R, Shaffrey CI, Asher AL, Heary RF, Cheng JS, Hurlbert RJ, Douglas AF, Smith JS, Malhotra NR, Dante SJ, Magge SN, Kaiser MG, Abbed KM, Resnick DK: Cost-Effectiveness of Lumbar Discectomy and Single Level Fusion for Spondylolisthesis: Experience with the NeuroPoint SD Registry Neurosurg Focus 36 (6): E3,2014.

Hunt J, Fang K, Snyder A, Malhotra NR: Ammonia Depletion in Asthma Diminishes Buffering of Endogenous Airway Acid Journal of Allergy and Clinical Immunology 105 (1): S193,2000.

Nayak NR, Stephen JH, Abdullah KG, Stein SC: Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study Global Spine J 6 (3): 270-6,2016.

Agarwal P, Burke JF, Abdullah KG, Piazza M, Smith BP, Thawani JP: Stab wound to the intramedullary spinal cord: Presurgical and surgical management options for a retained blade to optimize neurological preservation Surgical Neurol Int 7 (Suppl 42): S1096-S1098,2016.

Nayak NR, Bauman JA, Stein SC, Thawani JP: Surgical Approaches for the Treatment of Thoracic Disc Herniation: Results of a Decision Analysis Clin Spine Surg 30 (7): 901-908,2017.

Gorth DG, Martin JT, Dodge GR, Malhotra NR, Elliott DM, Mauck RL: In Vivo Retention and Bioactivity of IL-1ra Microspheres in the Rat Intervertebral Disc: a Preliminary Investigation Journal of Experimental Orthopaedics 1 (1): 15,2014.

Malhotra NR, Spiotta A, Jackson E, Maloney-Wilensky E: Effects of DVT Prophylaxis of Cerebral Oxygenation Pennsylvania Neurosurgical Society : 2004.

Stiefel M, Spiotta A, Gracias V, Heuer GG, Danish S, Magge S, Malhotra NR, Jackson E, Zaghloul K, Maloney E, Grady MS: Brain Tissue Oxygen-Guided Management Reduces Mortality in Traumatic Brain Injury Neurocritical Care Society : 2005.

Hunt JF, Fang K, Malik R, Snyder A, Malhotra NR, Platts-Mills TA: Endogenous Airway Acidification. Implications for Asthma Pathophysiology Am J Respir Crit Care Med 161 (3 part 1): 694-9,2000.

Hunt JF, Erwin E, Palmer L, Vaughan J, Malhotra NR, Platts-Mills TA: Expression and Activity of pH-Regulatory Glutaminase in the Human Airway Epithelium Am J Respir Crit Care Med 165 (1): 101-7,2002.

Gaston B, Ratjen F, Vaughan JW, Malhotra NR, Canady RG, Snyder AH, Hunt JF, Gaertig S: Nitrogen Redox Balance in the Cystic Fibrosis Airway: Effects of Antipseudomonal Therapy Am J Respir Crit Care Med 165 (3): 387-90,2002.

Boockvar JA, Stiefel M, Malhotra NR, Dolinskas C, Dwyer-Joyce C: Dural Cavernous Angioma of the Posterior Sagittal Sinus Surg Neurol 63 (2): 178-181,2005.

Academic Contact Info

Vice Chairman for Operations
Department of Neurological Surgery
3rd Floor Silverstein Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 615-5454
Patient appointments: 800-789-7366 (PENN)

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