Penn Medicine Provider
Trauma Surgery
Nathan J. Klingensmith, MD
Accepting new patients
Sees patients age 18 and up
Penn Traumatology, Surgical Critical Care and Emergency Surgery Perelman
View 1 additional location

About me

  • Assistant Professor of Surgery
  • Director of Education, Division of Traumatology, Surgical Critical Care, and Emergency Surgery Service
  • Assistant Professor of Surgery at the Hospital of the University of Pennsylvania

Education and training

  • Medical School: West Virginia University School of Medicine
  • Residency: Emory University
  • Fellowship: Emory University

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Klingensmith is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Lam LK, Klingensmith N, Sayegh L, Oatman E, Jose J, Cosgriff C, Eckart K, McGinnis J, Ranjan P, Lanza M, Yehya N, Meyer N, Dickson R, Mangalmurti N Red blood cell DNA capture and delivery drives host responses during polymicrobial sepsis , Research Square: 2024 (Preprint)


Bass GA, Kaplan LJ, Gaarder C, Coimbra R, Klingensmith NJ, Kurihara H, Zago M, Cioffi SPB, Mohseni S, Sugrue M, Tolonen M, Valcarcel CR, Tilsed J, Hildebrand F, Marzi I Publisher Correction: European Society for Trauma and Emergency Surgery member-identified research priorities in emergency surgery: A roadmap for future clinical research opportunities , European Journal of Trauma & Emergency Surgery: 2024 (Epub)


Metthew Lam LK, Oatman E, Eckart KA, Klingensmith NJ, Flowers E, Sayegh L, Yuen J, Clements RL, Meyer NJ, Jurado KA, Vaughan AE, Eisenbarth SC, Mangalmurti NS Human red blood cells express the RNA sensor TLR7 , Science Reports, 14(1): 2024,15789


Oatman E, Klingensmith N, Lam M, Eckart K, Meyer NJ, Mangalmurti NS Human red blood cells express toll-like receptor 7 and bind single stranded RNA , American Journal of Respiratory & Critical Care Medicine, 209: 2024


Bass GA, Kaplan LJ, Gaarder C, Coimbra R, Klingensmith NJ, Kurihara H, Zago M, Cioffi SPB, Mohseni S, Sugrue M, Tolonen M, Valcarcel CR, Tilsed J, Hildebrand F, Marzi I European Society for Trauma and Emergency Surgery member-identified research priorities in emergency surgery: A roadmap for future clinical research opportunities , European Journal of Trauma & Emergency Surgery, 50(2): 2024,367-382


Paterson CW, Fay KT, Chen CW, Klingensmith NJ, Gutierrez MB, Liang Z, Coopersmith CM, Ford ML CTLA-4 checkpoint inhibition improves sepsis survival in alcohol-exposed mice , Immunohorizons, 8(1): 2024,74-88


Noorbakhsh S, Gomez L, Joung Y, Meyer C, Hanos DS, Freedberg M, Klingensmith N, Grant AA, Koganti D, Nguyen J, Smith RN, Sciarretta JD Hepatic arterioportal fistula following liver trauma: Case series and review of the literature , Vascular & Endovascular Surgery, 57(7): 2023,749-755


Oami T, Yumoto T, Shimazui T, Sarmiento S, Klingensmith NJ, Chen CW, Otani S, Liang Z, Burd EM, Mahdi ZK, Ford ML, Coopersmith CM Chronic ethanol use worsens gut permeability and alters tight junction expression in a murine sepsis model , Shock, 60(2): 2023,280-290


Niziolek GM, Keating J, Bailey J, Klingensmith NJ, Moren AM, Skarupa DJ, Loria A, Vella MA, Maher Z, Moore SA, Smith MC, Leung A, Shuster KM, Seamon MJ Rethinking protocolized completion angiography following extremity vascular trauma: A prospective observational multicenter trial , Journal of Trauma & Acute Care Surgery, 95(1): 2023,105-110


Lam M, Eckart KA, Klingensmith NJ, Mangalmurti NS Deoxyribonucleic acid capture by red blood cells contributes to inflammation in sepsis , American Journal of Respiratory & Critical Care Medicine, 207: 2023,1


View all publications