Description of Research Expertise:
Aging, sleep, complementary/alternative medicine, melatonin, patient-oriented research, translational research, categorical data, clinical trials, multivariate analysis, time series.
Description of Research:
Dr. Gooneratne’s research interests are centered around studying the nature of sleep disorders in the elderly. While many older adults complain of difficulties with sleep, it is an area about which modern medicine has only a limited understanding. Funded initially by a National Institute on Aging Mentored Research Career Development Award (K23) and a National Center for Complementary and Alternative Medicine Research Award (R01), he is pursuing research examining the role of melatonin, a hormone secreted by the pineal gland, in sleep in the elderly. Dr. Gooneratne also has a strong interest in the attitudes of senior citizens towards their sleep problems and how their background/ethnicity informs their decisions. This project has been funded by a Hartford foundation/Penn Center for Excellence pilot grant. Dr.Gooneratne also runs a Sleep Disorders Clinic for Seniors in an effort to address the medical needs of older patients with sleep disorders. In addition, Dr. Gooneratne is the Associate Program Director of the Clinical and Translational Research Center of the University of Pennsylvania's Clinical and Translational Science Award, which assists in the conduct of over 190 clinical research studies. He also helps to coordinate the research activities of the Geriatric fellows in the Division of Geriatric Medicine and mentors research fellows in the Division of Sleep Medicine.
Gehrman P, Gooneratne NS, Brewster GS, Richards KC: Impact of Alzheimer disease patients' sleep disturbances on their caregivers. Geriatr Nurs : 2017.
Li J, Chang YP, Riegel B, Keenan BT, Varrasse M, Pack AI: Intermediate, But Not Extended, Afternoon Naps May Preserve Cognition in Chinese Older Adults.
J Gerontol A Biol Sci Med Sci : 2017.
Li J, Cacchione PZ, Hodgson N, Riegel B, Keenan BT, Scharf MT, Richards KC: Afternoon Napping and Cognition in Chinese Older Adults: Findings from the China Health and Retirement Longitudinal Study Baseline Assessment.
J Am Geriatr Soc 65 (2): 373-380,2017.
Pak, V.M., Onen, S-H., Gooneratne, N.S., Falissard, B., Onen: Observation and Interview-based Diurnal Sleepiness Inventory for Measurement of Sleepiness in Older Adults Nature and Science of Sleep accepted : 2017.
Sharma A., Barrett M.S., Cucchiara A.J., Gooneratne N.S.: A Breathing-Based Meditation Intervention for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Randomized Pilot Study J Clin Psychiatry : 2016.
Gooneratne: What is Academic Entrepreneurship? Academic Entrepreneurship in the Life Sciences: http://www.itmat.upenn.edu/mtr-entsci-blog/what-is-academic-entrepreneurship.html : 2016.
Onen F., Lalanne C., Pak V.M., Gooneratne N.S., Falissard B.: A Three-Item Instrument for Measuring Daytime Sleepiness: The Observation and Interview Based Diurnal Sleepiness Inventory (ODSI) J Clin Sleep Med 12 (4): 505-12,2016.
Gooneratne: Sleep Problems Specific to Geriatric Patients Sleep Medicine in Primary Care (electronic textbook) : 2016.
Gehrman P.R., Hall M., Barilla H., Buysse D., Perlis M., Gooneratne N.: Stress Reactivity in Insomnia Behav Sleep Med 14 (1): 23-33,2016.
Gooneratne: Sleep in older adults: normative changes, sleep disorders, and treatment options Clin Geriatr Med 30 (3): 591-627,2014.
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