Description of Research Expertise:
A primary goal of my research is to be a clinical investigator of industry sponsored grants testing the efficacy of drugs in pulmonary fibrosis or sarcoidosis.
A second goal of the research is to understand the granulomatous process in sarcoidosis. Lung specimens have been obtained and microbiome analysis performed to try to indentify organisms that might be involved in the etiology or natural course of sarcoidosis. In addition, analysis of proteome of the blood is taking place to try to identify signatures of particular phenotypes of sarcoidosis.
A third research goal is to utilize helium and zenon MRI to further understand the physiology of the lung and also to ultimately help diagnose and follow obstructive and interstitial lung disorders.
Sarcoidosis: association with human leukocyte antigen class II amino acid epitopes and interaction with environmental exposures Chest 121 (3 Suppl): 14S,2002.
Chronic beryllium disease: a hypersensitivity disorder Applied Occupational & Environmental Hygiene 16 (5): 615-18,2001.
Rossman, M.D., MacGregor: Tuberculosis: Clinical Management and New Challenges : 1995.
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