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Matthew H. Levine, MD, PhD

Matthew H. Levine, MD, PhD Surgeon

Assistant Professor of Surgery

Dr. Levine is a Penn Medicine employed physician.

In New Jersey, providers are affiliated with Penn Medicine through Clinical Health Care Associates of New Jersey.

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About Dr. Matthew H. Levine

Recognized in Philadelphia magazine's annual Top Docs issue for 2017

Clinical Specialties


  • Transplant Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2006

Clinical Expertise:

  • Allogeneic Transplant
  • Autologous Stem Cell Transplantation
  • Bile Duct Cancer
  • Bile Duct Tumor
  • Biliary Stenosis
  • Biliary Stricture (Bile Duct Stricture)
  • Biliary Surgery
  • Biliary Tract Disorders
  • Hepatobiliary Surgery
  • Hepatocellular Carcinoma (HCC)
  • Kidney Transplant Evaluation
  • Kidney Transplant Follow-Up
  • Kidney Transplantation
  • Laparoscopic Spleen Removal Surgery (Splenectomy)
  • Liver - Portal Hypertension
  • Liver Cancer
  • Liver Diseases
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection (Hepatic Resection)
  • Liver Transplant Evaluation
  • Liver Tumor Surgery
  • Liver Tumors
  • Organ Transplant and Cancer
  • Pancreas Transplantation
  • Polycystic Kidney Disease (PKD)
  • Spleen Removal Surgery (Splenectomy)
  • Transplant Immunology

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Vibra Health Plan

Education and Training

Medical School: Yale University School of Medicine
Residency: Massachusetts General Hospital
Fellowship: UCSF Medical Center and Hospital


American Association for the Study of Liver Diseases (AASLD), National American College of Surgeons , National American Society of Transplant Surgeons (ASTS), National American Society of Transplantation (AST), National Association for Academic Surgery (AAS), National Association of Academic Surgery , National Liver Transplantation Society, International Scientific Committee: American Society of Transplant Surgeons, National The Transplantation Society, International

Hospital Affiliation

Dr. Levine is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Clayton Erica F, Malik Saloni, Bonnel Alexander, Mu Yifei, Olthoff Kim, Shaked Abraham, Abt Peter L, Peterman Heather, Rajender Reddy K, Ottmann Shane, Furth Emma E, Levine Matthew H: Liver transplantation and cirrhotomimetic hepatocellular carcinoma: classification and outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20 (7): 765-74,2014.

Wolf Joshua H, Bhatti Tricia R, Fouraschen Suomi, Chakravorty Shourjo, Wang Liqing, Kurian Sunil, Salomon Daniel, Olthoff Kim M, Hancock Wayne W, Levine Matthew H: Heat shock protein 70 is required for optimal liver regeneration after partial hepatectomy in mice. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20 (3): 376-85,2014.

Diamond JM, Akimova T, Kazi A, Shah RJ, Cantu E, Feng R, Levine MH, Kawut SM, Meyer NJ, Lee JC, Hancock WW, Aplenc R, Ware LB, Palmer SM, Bhorade S, Lama VN, Weinacker A, Orens J, Wille K, Crespo M, Lederer DJ, Arcasoy S, Demissie E, Christie JD, Lung Transplant Outcomes Group.: Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. American Journal of Respiratory & Critical Care Medicine. 189 (5): 567-575,2014.

Yoo Peter S, Bonnel Alexander, Kamoun Malek, Levine Matthew H: Clinical outcomes among renal transplant recipients with pre-transplant weakly reactive donor-specific antibodies. Clinical transplantation 28 (1): 127-33,2014.

Levine MH.: Liver: Standard arterial reconstruction. Operative Techniques in Surgery. : 2013 (In press).

Levine M, Feng S.: Clinical allograft rejection syndromes: Diagnosis and management: Liver. Textbook of Organ Transplantation. : 2013 (In press).

Wolf J H, Sulewski M E, Cassuto J R, Levine M H, Naji A, Olthoff K M, Shaked A, Abt P L: Simultaneous thoracic and abdominal transplantation: can we justify two organs for one recipient? American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 13 (7): 1806-16,2013.

Parzych Elizabeth M, Li Hua, Yin Xiangfan, Liu Qin, Wu Te-Lang, Podsakoff Gregory M, High Katherine A, Levine Matthew H, Ertl Hildegund C J: Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humans. Human gene therapy 24 (4): 431-42,2013.

Wang Y, Bhatti T, Han R, Hancock W, Levine M: Pan-Histone Protein Deacetylase (HDAC) Inhibition Improves Renal Ischemia Reperfusion Injury Tolerance In A Non-Class-Specific Fashion American Transplant Congress, Boston, MA : 2012 .

Bahirwani R, Forde K, Mu Y, Lin F, Reese P, Abt P, Reddy R, Levine M: End Stage Renal Disease after Liver Transplantation in Patients with Pre-Transplant Chronic Kidney Disease American Transplant Congress, Boston, MA : 2012 .

Academic Contact Info

Division of Transplant Surgery
University of Pennsylvania Medical Center
3400 Spruce Street, 1 Founders Pavilion

Philadelphia, PA 19104
Phone: 215-662-7367
Patient appointments: 800-789-7366 (PENN)