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Matthew G. Denker, MD

Matthew G. Denker, MD Physician

Assistant Professor of Clinical Medicine

Dr. Denker is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Renal Electrolyte and Hypertension

Programs & Centers:

Board Certification:

  • Internal Medicine, 2010
  • Nephrology, 2012

Additional Certification:

  • American Society of Hypertension

Clinical Expertise:

  • Alport Syndrome
  • Berger's Disease (IgA Nephropathy)
  • Cardiorenal Syndrome (CRS)
  • Diabetic Kidney Diseases
  • Dialysis
  • Electrolyte Disorders
  • End-Stage Kidney Disease
  • Focal Segmental Glomerulosclerosis (FSGS)
  • Goodpasture Syndrome
  • Granulomatosis with Polyangiitis
  • Hemodialysis
  • Henoch–Schönlein purpura
  • HIV-Associated Nephropathy
  • Home Dialysis
  • Hypercalcemia
  • Hyperparathyroidism
  • Hypertension
  • Interstitial Cystitis (IC)
  • Kidney Cancer
  • Kidney Cyst (Renal Cyst)
  • Kidney Failure
  • Kidney Polycystic Diseases
  • Kidney Stones (Nephrolithiasis)
  • Kidney Transplant Rejection
  • Kidney Transplantation
  • Leg Swelling (Edema)
  • Living Donor Kidney Transplantation
  • Lupus Nephritis
  • Metabolic Acidosis
  • Nephritis
  • Nephrotic Syndrome
  • Nephrotoxicity
  • Partial Nephrectomy
  • Peritoneal Dialysis
  • Renal Disease and Pregnancy
  • Renal Osteodystrophy
  • Renovascular Hypertension
  • Ultrasound Guided Biopsy
  • Uremia
  • Vasculitis
View More

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Jefferson Medical College
Residency: Tufts - New England Medical Center
Fellowship: Hospital of the University of Pennsylvania


American Society of Hypertension, National American Society of Nephrology, International

Hospital Affiliation

Dr. Denker is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My clinical research focuses on hypertension as well as novel risk factors (e.g. uric acid) for chronic kidney disease progression.

Selected Publications:

Denker M, Boyle S, Anderson AH, Appel LJ, Chen J, Fink JC, Flack J, Go AS, Horwitz E, Hsu CY, Kusek JW, Lash JP, Navaneethan S, Ojo AO, Rahman M, Steigerwalt SP, Townsend RR, Feldman HI; Chronic Renal Insufficiency Cohort Study Investigators.: Chronic Renal Insufficiency Cohort (CRIC): overview and summary of selected findings CJASN 10 : 2015.

Denker MG, Cohen DL, Townsend RR: Catheter-based Renal Artery Denervation for Resistant Hypertension: Promise Unfulfilled or Unsettled? Current Atherosclerosis Reports 17 : 56,2015.

Denker MG, Cohen DL: Resistant Hypertension and Renal Nerve Denervation Methodist Debakey Cardiovascular Journal 11 : 2015.

Denker MG, Cohen DL: Antihypertensive Medications in End-Stage Renal Disease. Seminars in Dialysis 28 : 2015.

Denker MG, Cohen DL: Use of continuous positive airway pressure for sleep apnea in the treatment of hypertension Current Opinion in Nephrology and Hypertension 23 (5): 462-7,2014.

Denker MG, Haddad DB, Townsend RR, Cohen DL: Blood pressure control 1 year after referral to a hypertension specialist Journal of Clinical Hypertension 15 (9): 624-9,2013.

Denker MG, Roy JA, Feldman HI: Uric acid and risk of chronic kidney disease progression (Poster Presentation) American Society of Nephrology Annual Meeting, Atlanta, GA : 2013.

Denker MG, Cohen DL: What is an appropriate blood pressure goal for the elderly: review of recent studies and practical recommendations Journal of Clinical Interventions in Aging 8 : 1505-17,2013.

Academic Contact Info

Renal Office
1 Founders Pavilion
3400 Spruce St.

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)