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Mark A. Rosen, MD, PhD

Mark A. Rosen, MD, PhD Physician

Division Chief, Abdominal Imaging Associate Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Rosen is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 1999

Clinical Expertise:

  • Anal Cancer
  • Bile Duct Cancer
  • Bladder Cancer
  • Breast Cancer
  • Colon Cancer
  • Ductal Carcinoma in Situ (DCIS)
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrointestinal Carcinoid Tumor
  • Inflammatory Breast Cancer (IBC)
  • Invasive (Infiltrating) Ductal Carcinoma (IDC)
  • Invasive (Infiltrating) Lobular Carcinoma (ILC)
  • Kidney Cancer
  • Liver Cancer
  • Magnetic Resonance Imaging (MRI)
  • Male Breast Cancer
  • Neuroendocrine Tumors
  • Pancreatic Cancer
  • Penile Cancer
  • Prostate Cancer
  • Rectal Cancer
  • Small Intestine Cancer
  • Stomach Cancer (Gastric Cancer)
  • Testicular Cancer
  • Triple-Negative Breast Cancer
  • Urethral Cancer

Description of Clinical Expertise

Radiology, Abdominal Imaigng, MRI & CT

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Columbia University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Residency: Thomas Jefferson University Hospital
Fellowship: Hospital of the University of Pennsylvania


Abdominal Disease Site Committee American College of Radiology Imaging Network, National American College of Radiology, National American Roentgen Ray Society, National American Society of Clinical Oncology, National BMIT-A Study Section Biomedical Imaging Technology A National Institute of Health , National Breast DCE-MRI Working Group National Cancer Institute, National CACTIS, University of Pennsylvania, National CAMRIS, University of Pennsylvania , National Clinical Imaging Core, University of Pennsylvania, National CT/MRI Core Laboratory American College of Radiology Imaging Network , National Early Detection and Diagnosis Committee ECOG-ACRIN, National ECOG ACRIN, National Fluciclatide Renal Cell Carcinoma advisory board General Electric, Inc., International Gadovist Advisory Board, Bayer Pharmaceuticals, Inc., International Hepatobiliary Cancer Task Force National Cancer Institute, National Imaging Core Laboratory ECOG-ACRIN (Eastern College of Oncology Group / American College of Radiology Imaging Network), National International Society of Magnetic Resonance in Medicine, International NRG Radiation Oncology Committee , National Pendergrass Scientific Review Committee University of Pennsylvania , National Perfusion, Diffusion, Flow Committee Quantitative Imaging Biomarkers Alliance Radiologic Society of North America, National QIBA , National Radiological Society of North America, International Society of Computed Tomography & Magnetic Resonance, National Steering Committee American College of Radiology Imaging Network, National Study Section - Biomedical Imaging and Technology - A St. Louis, MO , National Study Section - Biomedical Imaging and Technology - A Washington, DC , National Study Section 2CAI SRCB-4 Early Stage Development of Information Technology National Institute of Health , National Study Section SBIB-J 90 Development of Methods for in vivo Imaging and Bioengineering Research National Institute of Health , National

Hospital Affiliation

Dr. Rosen is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Functional Tumor MR Imaging: DCE-MRI, DWI, MRSI
Morphologic Tumor Response Evaluation

Selected Publications:

Hylton Nola M, Gatsonis Constantine A, Rosen Mark A, Lehman Constance D, Newitt David C, Partridge Savannah C, Bernreuter Wanda K, Pisano Etta D, Morris Elizabeth A, Weatherall Paul T, Polin Sandra M, Newstead Gillian M, Marques Helga S, Esserman Laura J: Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL. Radiology 279 (1): 44-55,2016.

Narayan Vivek, Hwang Wei-Ting, Lal Priti, Rosen Mark A, Gallagher Maryann, O'Dwyer Peter J: Cyclin-Dependent Kinase 4/6 Inhibition for the Treatment of Unresectable Mature Teratoma: Long-Term Follow-Up of a Phase II Study. Clinical genitourinary cancer s1558-7673 (16): 30064-7,2016.

FitzGerald Thomas J, Bishop-Jodoin Maryann, Followill David S, Galvin James, Knopp Michael V, Michalski Jeff M, Rosen Mark A, Bradley Jeffrey D, Shankar Lalitha K, Laurie Fran, Cicchetti M Giulia, Moni Janaki, Coleman C Norman, Deye James A, Capala Jacek: Imaging and Data Acquisition in Clinical Trials for Radiation Therapy. International journal of radiation oncology, biology, physics 94 (2): 404-11,2016.

Flaherty Keith T, Hamilton Betty K, Rosen Mark A, Amaravadi Ravi K, Schuchter Lynn M, Gallagher Maryann, Chen Helen, Sehgal Chandra: Phase I/II Trial of Imatinib and Bevacizumab in Patients With Advanced Melanoma and Other Advanced Cancers. The Oncologist 20 (8): 952-9,2015.

Chung So Hyun, Feldman Michael D, Martinez Daniel, Kim Helen, Putt Mary E, Busch David R, Tchou Julia, Czerniecki Brian J, Schnall Mitchell D, Rosen Mark A, DeMichele Angela, Yodh Arjun G: Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures. Breast Cancer Research : BCR 17 : 72,2015.

Vaughn David J, Hwang Wei-Ting, Lal Priti, Rosen Mark A, Gallagher Maryann: Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors. Cancer 121 (9): 1463-8,2015.

Agner Shannon C, Rosen Mark A, Englander Sarah, Tomaszewski John E, Feldman Michael D, Zhang Paul, Mies Carolyn, Schnall Mitchell D: Computerized image analysis for identifying triple-negative breast cancers and differentiating them from other molecular subtypes of breast cancer on dynamic contrast-enhanced MR images: a feasibility study. Radiology 272 (1): 91-9,2014.

Shlansky-Goldberg Richard D, Rosen Mark A, Mondschein Jeffrey I, Stavropoulos S William, Trerotola Scott O: Comparison of polyvinyl alcohol microspheres and tris-acryl gelatin microspheres for uterine fibroid embolization: results of a single-center randomized study. Journal of vascular and interventional radiology : JVIR 25 (6): 823-32,2014.

Choe Regine, Putt Mary E, Carlile Peter M, Durduran Turgut, Giammarco Joseph M, Busch David R, Jung Ki Won, Czerniecki Brian J, Tchou Julia, Feldman Michael D, Mies Carolyn, Rosen Mark A, Schnall Mitchell D, DeMichele Angela: Optically measured microvascular blood flow contrast of malignant breast tumors. PLoS One 9 (6): e99683,2014.

Ciunci CA, Perini RF, Avadhani AN, Kang HC, Sun W, Redlinger M, Harlacker K, Flaherty KT, Giantonio BJ, Rosen MA, Divgi CR, Song HK, Englander S, Troxel A, Schnall M: Phase 1 and pharmacodynamic trial of everolimus in combination with cetuximab in patients with advanced cancer. Cancer 120 (1): 77-85,2014.

Academic Contact Info

Department of Radiology
Hospital of the University of Pennsylvania
1 Silverstein
3400 Spruce Street

Philadelphia, PA 19104-4283
Phone: (215) 662-3107
Patient appointments: 800-789-7366 (PENN)

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