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Mark A. Rosen, MD, PhD

Mark A. Rosen, MD, PhD Physician

Division Chief, Abdominal Imaging
Associate Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Rosen is a Penn Medicine employed physician.

Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 1999

Clinical Expertise:

  • Anal Cancer
  • Bile Duct Cancer
  • Bladder Cancer
  • Breast Cancer
  • Colon Cancer
  • Ductal Carcinoma in Situ (DCIS)
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrointestinal Carcinoid Tumor
  • Inflammatory Breast Cancer (IBC)
  • Invasive (Infiltrating) Ductal Carcinoma (IDC)
  • Invasive (Infiltrating) Lobular Carcinoma (ILC)
  • Kidney Cancer
  • Liver Cancer
  • Magnetic Resonance Imaging (MRI)
  • Male Breast Cancer
  • Neuroendocrine Tumors
  • Other types of Breast Cancer
  • Pancreatic Cancer
  • Penile Cancer
  • Prostate Cancer
  • Rectal Cancer
  • Small Intestine Cancer
  • Stomach Cancer (Gastric Cancer)
  • Testicular Cancer
  • Triple-Negative Breast Cancer
  • Urethral Cancer

Description of Clinical Expertise

Radiology, Abdominal Imaigng, MRI & CT

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Columbia University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Residency: Thomas Jefferson University Hospital
Fellowship: Hospital of the University of Pennsylvania


American College of Radiology, National American Society of Clinical Oncology, National BMIT-A Study Section Biomedical Imaging Technology A National Institute of Health, National CACTIS, University of Pennsylvania, National CAMRIS, University of Pennsylvania, National Clinical Imaging Core, University of Pennsylvania, National Early Detection and Diagnosis Committee ECOG-ACRIN, National ECOG ACRIN, National Hepatobiliary Cancer Task Force National Cancer Institute, National Imaging Core Laboratory ECOG-ACRIN (Eastern College of Oncology Group / American College of Radiology Imaging Network), National International Society of Magnetic Resonance in Medicine, International NRG Radiation Oncology Committee, National Pendergrass Scientific Review Committee University of Pennsylvania, National Perfusion, Diffusion, Flow Committee Quantitative Imaging Biomarkers Alliance Radiologic Society of North America, National QIBA, National Radiological Society of North America, International Study Section - Biomedical Imaging and Technology - A St. Louis, MO, National Study Section - Biomedical Imaging and Technology - A Washington, DC, National

Hospital Affiliation

Dr. Rosen is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Functional Tumor MR Imaging: DCE-MRI, DWI, MRSI
Morphologic Tumor Response Evaluation

Selected Publications:

Ciunci CA, Perini RF, Avadhani AN, Kang HC, Sun W, Redlinger M, Harlacker K, Flaherty KT, Giantonio BJ, Rosen MA, Divgi CR, Song HK, Englander S, Troxel A, Schnall M, O'Dwyer PJ: Phase 1 and pharmacodynamic trial of everolimus in combination with cetuximab in patients with advanced cancer. Cancer 120 (1): 77-85,2014.

Pentlicky S, Rosen M, Coffey PS, Kilbourne-Brook M, Shaunik A, Schreiber CA, Barnhart K: An exploratory, randomized, crossover MRI study of microbicide delivery with the SILCS diaphragm compared to a vaginal applicator Contraception 87 (2): 2013.

Busch DR, Choe R, Rosen MA, Guo W, Durduran T, Feldman MD, Mies C, Czerniecki BJ, Tchou J, Demichele A, Schnall MD, Yodh AG: Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy. Biomed Opt Express 4 (1): 105-21,2013.

Ashraf AB, Gavenonis SC, Daye D, Mies C, Rosen MA, Kontos D: A multichannel Markov random field framework for tumor segmentation with an application to classification of gene expression-based breast cancer recurrence risk IEEE Trans Med Imaging 32 (4): 637-48,2013.

Kang HC, Tan KS, Keefe SM, Heitjan DF, Siegelman ES, Flaherty KT, O'Dwyer PJ, Rosen MA: MRI assessment of early tumor response in metastatic renal cell carcinoma patients treated with sorafenib. AJR Am J Roentgenol 200 (1): 120-6,2013.

Hylton NM, Blume JD, Bernreuter WK, Pisano ED, Rosen MA, Morris EA, Weatherall PT, Lehman CD, Newstead GM, Polin S, Marques HS, Esserman LJ, Schnall MD: Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy - Results from ACRIN 6657/I-SPY TRIAL Radiology 263(3) : 663-672,2012.

Xue Y, Yu J, Kang HS, Englander S, Rosen MA, Song HK: Automatic coil selection for streak artifact reduction in radial MRI Magnetic Resonance in Medicine 67(2) : 470-476,2012.

Guzzo TJ, Resnick MJ, Canter DJ, Bivalacqua TJ, Rosen MA, Bergey MR, Magerfleisch L, Tomazewski JE, Wein AJ, Malkowicz SB: Endorectal T2-weighted MRI does not differentiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance Urologic Oncology: Seminars and Original Investigations 30(3) : 301-305,2012.

Rengan R, Mick R, Pryma D, Rosen MA, Lin LL, Maity AM, Evans TL, Stevenson JP, Langer CJ, Kucharczuk J, Friedberg J, Prendergast S, Sharkoski T, Hahn SM.: A phase I trial of the HIV protease inhibitor nelfinavir with concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small cell lung cancer: a report of toxicities and clinical response Journal Thoracic Oncology 7 (4): 709-15.,2012.

Toth R, Bloch BN, Genega EM, Rofsky NM, Lenkinski RE, Rosen MA, Kalyanpur A, Pungavkar S, Madabhushi A: Accurate prostate volume estimation using multifeature active shape models on T2-weighted MRI Academic Radiology 18(6) : 745-754,2011.

Academic Contact Info

Department of Radiology
Hospital of the University of Pennsylvania
1 Silverstein
3400 Spruce Street

Philadelphia, PA 19104-4283
Phone: (215) 662-3107
Fax: (215) 662-7263
Patient appointments: 800-789-PENN (7366)

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