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Mark Osterman, MD, MSCE

Mark Osterman, MD, MSCE Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia

Languages spoken:

  • Croatian

Dr. Osterman is a Penn Medicine employed physician.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Gastroenterology

Programs & Centers:

Board Certification:

  • Gastroenterology, 2005

Clinical Expertise:

  • Anal Cancer
  • Bile Duct Cancer
  • Colon Cancer
  • Crohn's Disease
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrointestinal Carcinoid Tumor
  • Inflammatory Bowel Disease (IBD)
  • Liver Cancer
  • Neuroendocrine Tumors
  • Pancreatic Cancer
  • Rectal Cancer
  • Small Intestine Cancer
  • Stomach Cancer (Gastric Cancer)

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Harvard Medical School
Residency: Brigham and Women's Hospital
Fellowship: Hospital of the University of Pennsylvania


Abbvie, International American Gastroenterological Association, National American Gastroenterological Association, National Crohn's and Colitis Foundation of America, National Elan Pharmaceuticals, National Janssen Pharmaceuticals, International Lycera, International Pfizer, National Takeda Pharmaceuticals, International UCB Worldwide, National

Hospital Affiliation

Dr. Osterman is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Lewis JD, Scott F, Brensinger CM, Roy JA, Osterman MT, Mamtani R, Chen L, Yun Huifeng, Xie F, Curtis JR: Reduced Mortality Rates with Anti-tumor Necrosis Factor Alpha Directed Therapy When Compared to Prolonged Corticosteroid Therapy for Inflammatory Bowel Disease Gastroenterology : 2017.

Herfarth HH, Jackson S, Schliebe B, Martin C, Ivanova A, Anton K, Sandler RS, Long MD, Isaacs KL, Osterman MT, Sands BE, Higgins PD, Lewis JD: Investigator initiated IBD trials in the US: Facts, obstacles and answers Inflammatory Bowel Diseases 23 (1): 14-22,2017.

Chachu KA, Osterman MT: How to diagnose and treat IBD mimics in the refractory IBD patient who does not have IBD Inflammatory Bowel Diseases 22 (5): 1262-74,2016.

Osterman MT, Lichtenstein GR: Chapter 116: Ulcerative Colitis Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 10th Edition : 2023-61,2016.

Osterman MT, Sandborn WJ, Colombel J-F, Peyrin-Biroulet L, Robinson AM, Zhou Q, Lewis JD: Crohn’s disease activity and concomitant immunosuppressants affect the risk of serious and opportunistic infections in patients treated with adalimumab American Journal of Gastroenterology 111 (12): 1806-15,2016.

Osterman MT, Roblin X, Glover S, Navaneethan U, Popa MA, Wyant T, James A, Lasch K, Rosario M: The relationship between vedolizumab drug concentrations at or before week 6 and remission at week 14 in ulcerative colitis patients from GEMINI 1 Gastroenterology 150 : S-105,2016.

Osterman MT, Lichtenstein GR: Medical treatment of perianal Crohn’s fistulae Pediatric Inflammatory Bowel Disease: Third Edition : 2016.

Zhang J, Xie F, Yun H, Chen L, Muntner P, Levitan EB, Safford MM, Kent ST, Osterman MT, Lewis JD, Saag K, Singh JA, Curtis JR: Comparative effects of biologics on coronary cardiovascular risk among older patients with rheumatoid arthritis Annals of the Rheumatic Diseases 75 (10): 1813-8,2016.

Mamtani R, Clark AS, Scott FI, Brensinger CM, Boursi B, Chen L, Xie F, Yun H, Osterman MT, Curtis JR, Lewis JD: Association between breast cancer recurrence with immunosuppression in rheumatoid arthritis and inflammatory bowel disease: a cohort study Arthritis and Rheumatology 68 (10): 2403-11,2016.

Vajravelu RK, Osterman MT, Aberra FN, Roy JA, Lichtenstein GR, Mamtani R, Goldberg DS, Lewis JD, Scott FI: Predictors and Clinical Impact of Indeterminate QuantiFERON-TB Gold Testing in Inflammatory Bowel Disease Pharmacoepidemiology and Drug Safety : 2016.

View all publications

Academic Contact Info

Penn Presbyterian Medical Center
Division of Gastroenterology
218 Wright-Saunders Building
51 North 39th Street

Philadelphia, PA 19104
Phone: (215) 662-8900
Fax: (215) 662-0950
Patient appointments: 800-789-PENN (7366)

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