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Dr. Grady was appointed the Charles Harrison Frazier Professor & Chairman of the Department of Neurosurgery at the Perelman School of Medicine, University of Pennsylvania in March 1999. He received his undergraduate degree from the University of California, San Diego and medical degree from Georgetown University School of Medicine. He trained in Neurological Surgery at the University of Virginia from 1981-1987 and was a faculty member at the University of Washington from 1987-1999. He is Board Certified by the American Board of Neurological Surgeons and is a fellow of the American College of Surgeons. Dr. Grady served as the Secretary for American Board of Neurological Surgery from 2004-2008, and was appointed Chairman of the ABNS from 2008-2009. Dr. Grady served as a member of the editorial board for the Journal of Neurosurgery from 2000-2010.

Dr. Grady's clinical focus is in the area of Cranial Base Tumors, Pituitary Tumors, Meningiomas, Schwannomas, Malignant Skull Base Tumors as well as Cerebrovascular Disorders, Aneurysms, AVM's. Dr. Grady and Dr. Bert O’Malley (Chairman, Department of Otorhinolaryngology - Head and Neck Surgery) are co-directors of the Cranial Base Center. In addition, Dr. Grady performs general neurosurgery procedures for herniated discs of the back and neck.

Medical School: Georgetown University School of Medicine
Residency: University of Virginia Health System

American Academy of Neurological Surgery, National American Association for the Advancement of Science, National American Association of Neurological Surgeons, National American Board of Neurological Surgery, National American College of Surgeons, National Cervical Spine Research Society, National College of Physicians of Philadelphia, Local John Morgan Society, Local Joint Section, Neurotrauma & Critical Care (AANS/CNS), National Joint Section, Spine & Peripheral Nerves (AANS/CNS), National Neurosurgical Society of America, National Neurotrauma Society, National Pennsylvania Medical Society, Local Pennsylvania Neurosurgical Society, Local Philadelphia Neurological Society, Local Society of Neurological Surgeons, National Union League of Philadelphia, Local

Hospital Privileges:

• Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
• Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
• Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Description of Research Expertise:

Dr. Grady's research interests include memory dysfunction resulting from traumatic brain injury and minimally invasive neurosurgery.

Selected Publications:

Lee JYK, Cho SS, Zeh R, Pierce JT, Martinez-Lage M, Adappa ND, Palmer JN, Newman JG, Learned KO, White C, Kharlip J, Snyder P, Low PS, Singhal S, Grady MS: Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging. J Neurosurg 129 (2): 390-403,2018.

Piazza M, Sharma N, Osiemo B, McClintock S, Missimer E, Gardiner D, Maloney E, Callahan D, Smith JL, Welch W, Schuster J, Grady MS, Malhotra NR: Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population. Neurosurgery : 2018.

Cho SS, Zeh R, Pierce JT, Jeon J, Nasrallah M, Adappa ND, Palmer JN, Newman JG, White C, Kharlip J, Snyder P, Low P, Singhal S, Grady MS, Lee JYK: Folate Receptor Near-Infrared Optical Imaging Provides Sensitive and Specific Intraoperative Visualization of Nonfunctional Pituitary Adenomas. Oper Neurosurg : 2018.

Swanson RL, Hampton S, Green-McKenzie J, Diaz-Arrastia R, Grady MS, Verma R, Biester R, Duda D, Wolf RL, Smith DH: Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba. JAMA 319 (11): 1125-1133,2018.

Ali ZS, Ma TS, Ozturk AK, Malhotra NR, Schuster JM, Marcotte PJ, Grady MS, Welch WC: Pre-optimization of spinal surgery patients: Development of a neurosurgical enhanced recovery after surgery (ERAS) protocol. Clin Neurol Neurosurg 164 : 142-153,2018.

Morris J, Na YJ, Zhu H, Lee JH, Giang H, Ulyanova AV, Baltuch GH, Brem S, Chen HI, Kung DK, Lucas TH, O'Rourke DM, Wolf JA, Grady MS, Sul JY, Kim J, Eberwine J: Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing. Cell Rep 21 (10): 2706-2713,2017.

Ma TS, Sharma N, Grady MS: A simplified pressure adjustment clinical pathway for programmable valves in NPH patients. Clin Neurol Neurosurg 159 : 83-86,2017.

Piazza M, Nayak N, Ali Z, Heuer G, Sanborn M, Stein S, Schuster J, Grady MS, Malhotra NR: Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms. World Neurosurg 103 : 194-200,2017.

Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK: Concussion Induces Hippocampal Circuitry Disruption in Swine. J Neurotrauma 34 (14): 2303-2314,2017.

Thawani JP, Ramayya AG, Pisapia JM, Abdullah KG, Lee JY, Grady MS: Operative Strategies to Minimize Complications Following Resection of Pituitary Macroadenomas. J Neurol Surg B Skull Base 78 (2): 184-190,2017.

Exploring Pituitary Tumors

Department of Neurosurgery website

Academic Profile

Penn Medicine Neuroscience Center website