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M. Sean Grady, MD

M. Sean Grady, MD Physician

Chairman, Department of Neurosurgery Physician Director, Neuroscience Service Line Professor of Otorhinolaryngology: Head and Neck Surgery Charles Harrison Frazier Professor of Neurosurgery

Dr. Grady is employed by Penn Medicine.

About Dr. M. Sean Grady

Recognized by America's Top Doctors, 2007, 2008, 2010, 2012 - 2018

Recognized by Best Doctors in America 2003 - 2018

Recognized annually in Philadelphia magazine's Top Docs issues from 2004 to 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Clinical Expertise:

  • Abnormal Vertebrae
  • Acoustic Neurofibromatosis
  • Acoustic Neuroma (Vestibular Schwannoma)
  • Acoustic Neuroma Removal
  • Acromegaly
  • Anaplastic Astrocytoma
  • Anaplastic Ependymoma
  • Anaplastic Mixed Glioma
  • Anaplastic Oligoastrocytoma
  • Anterior Temporal Lobectomy
  • Anterior Vertebral Body Tethering
  • Aqueductal Stenosis
  • Arachnoid Cyst
  • Arnold Chiari Malformation
  • Arteriovenous Malformations (AVM)
  • Astrocytic Cancer
  • Astrocytoma Tumors
  • Auditory Brainstem Implant
  • Awake Craniotomy
  • Back Injuries
  • Back Surgery
  • Benign Neoplasm of Brain
  • Biological Enhancement of Spinal Fusion
  • Biopsy of the Brain
  • Biopsy of the Skull
  • Bone Cyst
  • Bone Tumors
  • Brain Cancer Genomics
  • Brain Laceration
  • Brain Metastasis
  • Brain Surgery
  • Brain Tumor Bleeding
  • Brain Tumors
  • Bulging Disc
  • Burr Hole
  • Cauda Equina Syndrome
  • Cavernous Hemangioma
  • Cavernous Sinus Thrombosis
  • Central Nervous System Infection
  • Central Nervous System Tumors
  • Central Venous Stenosis
  • Cerebellar Tumor
  • Cerebral Angiogram
  • Cerebral Cyst
  • Cerebral Decompression
  • Cerebral Edema
  • Cerebral Hernia
  • Cerebrospinal Fluid (CSF) Leak
  • Cerebrovascular Accident
  • Cervical Arthritis
  • Cervical Bone Spur
  • Cervical Compression Fracture
  • Cervical Decompression
  • Cervical Deformity
  • Cervical Disc Degeneration
  • Cervical Disc Disease
  • Cervical Disc Displacement
  • Cervical Disc Herniation
  • Cervical Laminoplasty
  • Cervical Laminotomy
  • Cervical Radiculopathy
  • Cervical Revision Surgery
  • Cervical Spinal Fracture
  • Cervical Spinal Fusion Surgery
  • Cervical Spinal Stenosis
  • Cervical Spine Surgery
  • Cervical Steroid Injection
  • Chiari Decompression
  • Cholesteatoma
  • Chordoma
  • Choroid Plexus Tumor
  • Clivus Chondroma
  • CNS Lymphoma
  • Colloid Cyst
  • Complex Spinal Surgery
  • Compression Fractures
  • Cordotomy
  • Corpus Callosotomy Surgery
  • Cortical Mapping
  • Cranial Nerve Disorders
  • Cranial Nerve Injuries
  • Cranial Nerve Palsy
  • Cranial Nerve Repair
  • Cranial Puncture
  • Craniectomy
  • Craniocele
  • Craniocervical Junction Surgery
  • Craniopharyngioma
  • Craniotomy
  • CSF Shunt Removal
  • Decompression Laminectomy
  • Degenerative Spine Conditions
  • Disc Surgery
  • Diskectomy
  • Dorsal Column Stimulator
  • Dural Arteriovenous Fistula
  • Dural Based Tumor
  • Dural Sinus Thrombosis
  • EGFR Translocation
  • Electrocorticography
  • Embryonal Cell Tumors of the Brain
  • Embryonal Tumors
  • Encephalocele Repair
  • Endodermal Sinus Tumor
  • Endonasal Transsphenoidal Approach
  • Endoscopic Endonasal Approach
  • Endoscopic Fusion
  • Endoscopic Neurosurgery
  • Endoscopic Third Ventriculostomy
  • Ependymoma
  • Epidural Hematoma
  • Epidural Hemorrhage
  • Epidural Injection
  • Epilepsy
  • Epilepsy Surgery
  • Evaluation for Epilepsy Surgery
  • Extradural Abscess
  • Facial Nerve Schwannoma
  • Facial Pain
  • Facial Spasm
  • Fibrillary Astrocytoma
  • Foot Drag
  • Ganglioglioneurocytoma
  • Ganglioma
  • Ganglioneuroblastoma
  • Ganglioneurocytoma
  • Germ Cell Tumors
  • Germinoma
  • Glioblastoma
  • Glioma
  • Gliomatosis Cerebri
  • Gliosarcoma
  • Glomus Jugulare Tumor
  • Glossopharyngeal Neuralgia
  • Head and Neck Osteoma
  • Head Reconstruction
  • Hemangioblastoma
  • Hemangiopericytoma
  • Hemispherectomy
  • Herniated Disc
  • Hydrocephalus
  • Hypothalamic Hamartoma
  • Image Guided Biopsy of the Spine
  • Injury of Optic Chiasm
  • Intracranial Abscess
  • Intracranial Arterial Bypass
  • Intracranial Arterial Occlusion
  • Intracranial Hemangioma
  • Intracranial Hemorrhage
  • Intracranial Hypotension
  • Intracranial Mass
  • Intraoperative MRI
  • Intraspinal Abscess
  • Intraventricular Endoscopy
  • Intraventricular Tumor
  • Juvenile Nasopharyngeal Angiofibroma (JNA)
  • Laminectomy
  • Laminoplasty
  • Leptomeningeal Carcinomatosis
  • Leptomeningeal Disease
  • Lesionectomies
  • Lesionectomy
  • Lhermitte-Duclos Disease
  • Lipomyelomeningocele
  • Lobectomy of Brain
  • Low Back Surgery
  • Lower Back Injuries
  • Lower Back Pain
  • Lumbar Drain
  • Lumbar Scoliosis
  • Lumbar Spinal Fracture
  • Lumbar Spinal Fusion
  • Lumbar Spinal Injury
  • Lumbar Spinal Mass
  • Lumbar Spinal Stenosis
  • Lumbar Spinal Tumor
  • Lumbar Stress Fracture
  • Lumboperitoneal Shunt Placement
  • Lumbosacral Radiculopathy
  • Malignant Neoplasm of the Brain Stem
  • Malignant Neoplasm of the Cerebellum
  • Malignant Neoplasm of the Frontal Lobe
  • Malunion Fracture of the Spine
  • Medulloblastoma
  • Medulloepithelioma
  • Meningioma
  • Meningocele
  • Metastatic Brain Cancer
  • Microdiscectomy
  • Microneurosurgery
  • Microsurgery
  • Microvascular Decompression
  • Microvascular Surgery
  • Minimally Invasive Partial Lumbar Discectomy
  • Minimally Invasive Spinal Fusion
  • Minimally Invasive Spine Surgery
  • Minimally Invasive Surgery
  • Moyamoya
  • Myelopathy
  • Myelopathy Surgery
  • Myxopapillary Ependymoma
  • Neck Injuries
  • Neck Masses and Lumps
  • Neck Tumors
  • Needle Biopsy of Brain
  • Needle Biopsy of Cerebral Meninges
  • Neoplasm of Brain Stem
  • Nerve Sheath Tumor
  • Neuroblastoma
  • Neurocutaneous Disorders
  • Neuroectodermal Tumor
  • Neuroendocrine Tumors
  • Neuroendoscopy
  • Neurofibromatosis
  • Neurofibromatosis Type 1 (NF1)
  • Neurofibromatosis Type 2
  • Neurofibrosarcoma
  • Neurogenic Claudication
  • Neurointerventional Biplane Angiography System
  • Neuromuscular Scoliosis
  • Neuronal Glial Tumors
  • Nonruptured Cerebral Aneurysm
  • Normal Pressure Hydrocephalus
  • Occipito-Cervical Fusion
  • Olfactory Neuroblastoma
  • Oligoastrocytoma
  • Oligodendroglioma
  • Open Biopsy of the Brain
  • Optic Nerve Decompression
  • Optic Nerve Glioma
  • Optic Nerve Sheath Meningioma
  • Optic Nerve Surgery
  • Orbital Nerve Decompression
  • Orbital Tumors
  • Osteoarthritis of the Spine
  • Paraganglioma
  • Parkinson's Disease
  • Parkinson's Surgery
  • Percutaneous Trigeminal Rhizotomy
  • Peripheral Nerve Disorders
  • Peripheral Nerve Surgery
  • Peripheral Nerve Tumors
  • Peripheral Schwannoma
  • Periventricular Lesion
  • Periventricular Mass
  • Petrous Apex Tumor
  • Pilocytic Astrocytoma
  • Pineal Gland Parenchymal Tumor
  • Pineal Tumor
  • Pineoblastoma
  • Pituitary Adenoma
  • Pituitary Surgery
  • Pituitary Tumors
  • Posterior Cervical Laminectomy and Fusion
  • Posterior Lumbar Laminectomy
  • Post-Laminectomy Kyphosis
  • Post-Laminectomy Syndrome
  • Primary Brain Tumor
  • Prolactinoma
  • Radiculopathy
  • Rathke's Cleft Cysts
  • Repair of Brain
  • Retinoblastoma
  • Revision of Spinal Surgery
  • Rhizotomy
  • Robotic Spine Surgery
  • Ruptured Intervertebral Disc
  • Schwannomatosis
  • Sciatica
  • Scoliosis Surgery
  • Selective Dorsal Rhizotomy
  • Sinonasal Undifferentiated Carcinoma
  • Skull Base Approach
  • Skull Base Tumors
  • Skull Fracture
  • Spinal Abscess
  • Spinal Abscess Surgery
  • Spinal Cord Cancer
  • Spinal Cord Compression
  • Spinal Cord Disorder
  • Spinal Cord Stimulator
  • Spinal Cord Surgery
  • Spinal Cord Tumors
  • Spinal Cyst Removal
  • Spinal Dural Graft
  • Spinal Embolization
  • Spinal Fracture
  • Spinal Fusion
  • Spinal Instrumentation
  • Spinal Mass
  • Spinal Meningioma
  • Spinal Microsurgery
  • Spinal Reconstruction
  • Spinal Schwannoma
  • Spinal Stenosis
  • Spinal Tethering for Scoliosis
  • Spinal Tumor
  • Spine Decompression
  • Spine Deformity Correction Surgery
  • Spine Injuries
  • Spine Stapling
  • Spondylectomy
  • Spondyloarthropathy
  • Spondylolisthesis
  • Spondylosis
  • Spondylosis Surgery
  • Spondylosis With Myelopathy
  • Spondylosyndesis
  • Spongioblastoma
  • Standard Transsphenoidal Approach
  • Stereotactic Brain Biopsy
  • Stereotactic EEG
  • Stereotactic Radiosurgery
  • Stereotactic Radiotherapy
  • Subarachnoid Hemorrhage
  • Subdural Hematoma
  • Subdural Hemorrhage
  • Subependymal Giant Cell Astrocytoma
  • Superior Canal Dehiscence
  • Surgery for Sciatica
  • Surgical Treatment of Myelopathy
  • Syringobulbia
  • Syringomyelia
  • Temporal Tumor
  • Tethered Spinal Cord
  • Thoracic Disc Herniation
  • Thoracic Laminectomy
  • Thoracic Spinal Fracture
  • Thoracic Spinal Fusion
  • Thoracic Spinal Injury
  • Thoracic Spinal Mass
  • Thoracic Spinal Stenosis
  • Thoracic Spinal Tumor
  • Transnasal Repair CSF Leak
  • Transpetrosal Approaches
  • Trigeminal Nerve Disorders
  • Ulnar Nerve Decompression
  • Ulnar Nerve Surgery
  • Vagal Nerve Stimulator
  • Vagal Stimulation
  • Vascular Brain Tumors
  • Vein of Galen Malformation
  • Ventricular Shunt
  • Ventriculo Peritoneal Shunt
  • Ventriculocisternostomy
  • Ventriculostomy
  • Vertebrae Surgery
  • Vertebral Fracture
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Georgetown University School of Medicine
Residency: University of Virginia Health System

Memberships

American Academy of Neurological Surgery, National American Association for the Advancement of Science, National American Association of Neurological Surgeons, National American Board of Neurological Surgery, National American College of Surgeons, National Cervical Spine Research Society, National College of Physicians of Philadelphia, Local John Morgan Society, Local Joint Section, Neurotrauma & Critical Care (AANS/CNS), National Joint Section, Spine & Peripheral Nerves (AANS/CNS), National Neurosurgical Society of America, National Neurotrauma Society, National Pennsylvania Medical Society, Local Pennsylvania Neurosurgical Society, Local Philadelphia Neurological Society, Local Society of Neurological Surgeons, National Union League of Philadelphia, Local

Hospital Affiliation

Dr. Grady is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Dr. Grady's research interests include memory dysfunction resulting from traumatic brain injury and minimally invasive neurosurgery.

Selected Publications:

Lee JYK, Cho SS, Zeh R, Pierce JT, Martinez-Lage M, Adappa ND, Palmer JN, Newman JG, Learned KO, White C, Kharlip J, Snyder P, Low PS, Singhal S, Grady MS: Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging. J Neurosurg 129 (2): 390-403,2018.

Piazza M, Sharma N, Osiemo B, McClintock S, Missimer E, Gardiner D, Maloney E, Callahan D, Smith JL, Welch W, Schuster J, Grady MS, Malhotra NR: Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population. Neurosurgery : 2018.

Cho SS, Zeh R, Pierce JT, Jeon J, Nasrallah M, Adappa ND, Palmer JN, Newman JG, White C, Kharlip J, Snyder P, Low P, Singhal S, Grady MS, Lee JYK: Folate Receptor Near-Infrared Optical Imaging Provides Sensitive and Specific Intraoperative Visualization of Nonfunctional Pituitary Adenomas. Oper Neurosurg : 2018.

Swanson RL, Hampton S, Green-McKenzie J, Diaz-Arrastia R, Grady MS, Verma R, Biester R, Duda D, Wolf RL, Smith DH: Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba. JAMA 319 (11): 1125-1133,2018.

Ali ZS, Ma TS, Ozturk AK, Malhotra NR, Schuster JM, Marcotte PJ, Grady MS, Welch WC: Pre-optimization of spinal surgery patients: Development of a neurosurgical enhanced recovery after surgery (ERAS) protocol. Clin Neurol Neurosurg 164 : 142-153,2018.

Morris J, Na YJ, Zhu H, Lee JH, Giang H, Ulyanova AV, Baltuch GH, Brem S, Chen HI, Kung DK, Lucas TH, O'Rourke DM, Wolf JA, Grady MS, Sul JY, Kim J, Eberwine J: Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing. Cell Rep 21 (10): 2706-2713,2017.

Ma TS, Sharma N, Grady MS: A simplified pressure adjustment clinical pathway for programmable valves in NPH patients. Clin Neurol Neurosurg 159 : 83-86,2017.

Piazza M, Nayak N, Ali Z, Heuer G, Sanborn M, Stein S, Schuster J, Grady MS, Malhotra NR: Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms. World Neurosurg 103 : 194-200,2017.

Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK: Concussion Induces Hippocampal Circuitry Disruption in Swine. J Neurotrauma 34 (14): 2303-2314,2017.

Thawani JP, Ramayya AG, Pisapia JM, Abdullah KG, Lee JY, Grady MS: Operative Strategies to Minimize Complications Following Resection of Pituitary Macroadenomas. J Neurol Surg B Skull Base 78 (2): 184-190,2017.

Academic Contact Info

HUP - 3 Silverstein
3400 Spruce Street
clinical: 215.662.3483
administrative: 215.349.8325

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)

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