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M. Sean Grady, MD

M. Sean Grady, MD Physician

Chairman, Department of Neurosurgery Professor of Otorhinolaryngology: Head and Neck Surgery Charles Harrison Frazier Professor of Neurosurgery Charles Harrison Frazier Professor of Neurosurgery

Dr. Grady is employed by Penn Medicine.

About Dr. M. Sean Grady

Recognized by America's Top Doctors, 2007, 2008, 2010, 2012 - 2018

Recognized by Best Doctors in America 2003 - 2018

Recognized annually in Philadelphia magazine's Top Docs issues from 2004 to 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Clinical Expertise:

  • Abnormal Vertebrae
  • Absent Vertebrae
  • Accessory Nerve Injury
  • Acoustic Neurofibromatosis
  • Acoustic Neuroma (Vestibular Schwannoma)
  • Acoustic Neuroma Removal
  • Acromegaly
  • Anaplastic Astrocytoma
  • Anaplastic Ependymoma
  • Anaplastic Mixed Glioma
  • Anaplastic Oligoastrocytoma
  • Aneurysms
  • Ankylosing Spondylitis
  • Anterior Temporal Lobectomy
  • Anterior Vertebral Body Tethering
  • Aqueductal Stenosis
  • Arachnoid Cyst
  • Arnold Chiari Malformation
  • Arterial Malformation of the Brain
  • Arteriovenous Malformations (AVM)
  • Artificial Disc Replacement Surgery in the Cervical Spine
  • Artificial Disc Replacement Surgery in the Lumbar Spine
  • Astrocytic Cancer
  • Astrocytoma Tumors
  • Auditory Brainstem Implant
  • AVM Embolization
  • Awake Craniotomy
  • Back Injuries
  • Back Surgery
  • Benign Neoplasm of Brain
  • Berry Aneurysm
  • Biological Enhancement of Spinal Fusion
  • Biopsy of the Brain
  • Biopsy of the Skull
  • Bone Cyst
  • Bone Growth Stimulator
  • Bone Tumors
  • Brachial Nerve Tumors
  • Brachial Plexus Injury
  • Brain Cancer Genomics
  • Brain Laceration
  • Brain Metastasis
  • Brain Surgery
  • Brain Tumor Bleeding
  • Brain Tumors
  • Broken Coccyx
  • Bulging Disc
  • Burr Hole
  • Carotid Stenosis
  • Cauda Equina Syndrome
  • Cavernous Hemangioma
  • Cavernous Sinus Thrombosis
  • Central Nervous System Tumors
  • Central Venous Stenosis
  • Cerebellar Tumor
  • Cerebral Aneurysm
  • Cerebral Angiogram
  • Cerebral Angiogram with Aneurysm Embolization
  • Cerebral Angiogram with Coiling
  • Cerebral Angiogram with Stenting
  • Cerebral Artery Bypass Surgery
  • Cerebral Cyst
  • Cerebral Decompression
  • Cerebral Edema
  • Cerebral Hernia
  • Cerebral Revascularization
  • Cerebrospinal Fluid (CSF) Leak
  • Cerebrovascular Accident
  • Cerebrovascular Bypass Surgery
  • Cervical Arthritis
  • Cervical Bone Spur
  • Cervical Compression Fracture
  • Cervical Decompression
  • Cervical Deformity
  • Cervical Disc Degeneration
  • Cervical Disc Disease
  • Cervical Disc Displacement
  • Cervical Disc Herniation
  • Cervical Laminoplasty
  • Cervical Laminotomy
  • Cervical Radiculopathy
  • Cervical Revision Surgery
  • Cervical Spinal Fracture
  • Cervical Spinal Fusion Surgery
  • Cervical Spinal Stenosis
  • Cervical Spine Surgery
  • Cervical Steroid Injection
  • Chiari Decompression
  • Cholesteatoma
  • Chordoma
  • Choroid Plexus Tumor
  • Cingulotomy
  • Clipping of Brain Aneurysm
  • Clivus Chondroma
  • CNS Lymphoma
  • Coccyx Injury
  • Colloid Cyst
  • Common Carotid Artery Embolization
  • Complex Spinal Deformities
  • Complex Spinal Surgery
  • Compression Fractures
  • Congenital Malformation of the Spine
  • Congenital Scoliosis
  • Cordotomy
  • Corpus Callosotomy Surgery
  • Cortical Mapping
  • Cranial Nerve Disorders
  • Cranial Nerve Injuries
  • Cranial Nerve Palsy
  • Cranial Nerve Repair
  • Cranial Puncture
  • Craniectomy
  • Craniocele
  • Craniocervical Junction Surgery
  • Craniopharyngioma
  • Craniotomy
  • CSF Shunt Removal
  • Decompression Laminectomy
  • Decompression Median Nerve At Elbow
  • Deep Brain Stimulation
  • Deep Brain Stimulation for Dystonia
  • Deep Brain Stimulation while Asleep
  • Deep Brain Stimulation while Awake
  • Degenerative Spine Conditions
  • Disc Arthroplasty
  • Disc Replacement
  • Disc Surgery
  • Diskectomy
  • Dorsal Column Stimulator
  • Dural Arteriovenous Fistula
  • Dural Based Tumor
  • Dural Sinus Thrombosis
  • Dystonia
  • EGFR Translocation
  • Electrocorticography
  • Embryonal Cell Tumors of the Brain
  • Embryonal Tumors
  • Encephalocele Repair
  • Endodermal Sinus Tumor
  • Endonasal Transsphenoidal Approach
  • Endoscopic Endonasal Approach
  • Endoscopic Fusion
  • Endoscopic Neurosurgery
  • Endoscopic Third Ventriculostomy
  • Ependymoma
  • Epidural Hematoma
  • Epidural Hemorrhage
  • Epidural Injection
  • Epilepsy
  • Epilepsy Surgery
  • Erdheim-Chester Disease
  • Essential Tremor
  • Evaluation for Epilepsy Surgery
  • Extradural Abscess
  • Extreme Lateral Interbody Fusion
  • Facet Injection
  • Facet Surgery
  • Facial Nerve Schwannoma
  • Facial Pain
  • Facial Spasm
  • Failed Back Surgery Syndrome (FBSS)
  • Fibrillary Astrocytoma
  • Flatback Syndrome Post Harrington Rods
  • Flow Diversion for Cerebral Aneurysms
  • Foot Drag
  • Gamma Knife
  • Gamma Knife Perfexion
  • Ganglioglioneurocytoma
  • Ganglioma
  • Ganglioneuroblastoma
  • Ganglioneurocytoma
  • Germ Cell Tumors
  • Germinoma
  • Glioblastoma
  • Glioma
  • Gliomatosis Cerebri
  • Gliosarcoma
  • Glomus Jugulare Tumor
  • Glossopharyngeal Neuralgia
  • Growing Rods
  • Head and Neck Osteoma
  • Head Reconstruction
  • Hemangioblastoma
  • Hemangiopericytoma
  • Hemispherectomy
  • Herniated Disc
  • Hydrocephalus
  • Hypothalamic Hamartoma
  • Image Guided Biopsy of the Spine
  • Injury of Optic Chiasm
  • Intracranial Abscess
  • Intracranial Arterial Bypass
  • Intracranial Arterial Occlusion
  • Intracranial Hemangioma
  • Intracranial Hemorrhage
  • Intracranial Hypotension
  • Intracranial Mass
  • Intraoperative MRI
  • Intraspinal Abscess
  • Intraventricular Endoscopy
  • Intraventricular Tumor
  • Junctional Kyphosis
  • Juvenile Nasopharyngeal Angiofibroma (JNA)
  • Kyphosis
  • Laminectomy
  • Laminoplasty
  • Lateral Access Spine Surgery
  • Leptomeningeal Carcinomatosis
  • Leptomeningeal Disease
  • Lesion of Median Nerve
  • Lesion of Popliteal Nerve
  • Lesion of Posterior Tibial Nerve
  • Lesion of Sciatic Nerve
  • Lesionectomies
  • Lesionectomy
  • Lhermitte-Duclos Disease
  • Lipomyelomeningocele
  • Lobectomy of Brain
  • Low Back Surgery
  • Lower Back Injuries
  • Lower Back Pain
  • Lumbar Drain
  • Lumbar Scoliosis
  • Lumbar Spinal Fracture
  • Lumbar Spinal Fusion
  • Lumbar Spinal Injury
  • Lumbar Spinal Mass
  • Lumbar Spinal Stenosis
  • Lumbar Spinal Tumor
  • Lumbar Stress Fracture
  • Lumboperitoneal Shunt Placement
  • Lumbosacral Plexus Lesion
  • Lumbosacral Radiculopathy
  • Malignant Neoplasm of the Brain Stem
  • Malignant Neoplasm of the Cerebellum
  • Malignant Neoplasm of the Frontal Lobe
  • Malunion Fracture of the Spine
  • Medulloblastoma
  • Medulloepithelioma
  • Meningioma
  • Meningocele
  • Metastatic Brain Cancer
  • Microdiscectomy
  • Microneurosurgery
  • Microsurgery
  • Microvascular Decompression
  • Microvascular Surgery
  • Minimally Invasive Partial Lumbar Discectomy
  • Minimally Invasive Spinal Fusion
  • Minimally Invasive Spine Surgery
  • Minimally Invasive Surgery
  • Moyamoya
  • Myelopathy
  • Myelopathy Surgery
  • Myxopapillary Ependymoma
  • Neck Masses and Lumps
  • Neck Tumors
  • Needle Biopsy of Brain
  • Needle Biopsy of Cerebral Meninges
  • Neoplasm of Brain Stem
  • Nerve Sheath Tumor
  • Neuroblastoma
  • Neurocutaneous Disorders
  • Neuroectodermal Tumor
  • Neuroendocrine Tumors
  • Neuroendoscopy
  • Neurofibromatosis
  • Neurofibromatosis Type 1 (NF1)
  • Neurofibromatosis Type 2
  • Neurofibrosarcoma
  • Neurogenic Claudication
  • Neurointerventional Biplane Angiography System
  • Neuromuscular Scoliosis
  • Neuronal Glial Tumors
  • Nonruptured Cerebral Aneurysm
  • Normal Pressure Hydrocephalus
  • Occipito-Cervical Fusion
  • Olfactory Neuroblastoma
  • Oligoastrocytoma
  • Oligodendroglioma
  • Open Biopsy of the Brain
  • Optic Nerve Decompression
  • Optic Nerve Glioma
  • Optic Nerve Sheath Meningioma
  • Optic Nerve Surgery
  • Orbital Nerve Decompression
  • Orbital Tumors
  • Osteoarthritis of the Spine
  • Paraganglioma
  • Parkinson's Disease
  • Parkinson's Surgery
  • Percutaneous Trigeminal Rhizotomy
  • Peripheral Nerve Disorders
  • Peripheral Nerve Surgery
  • Peripheral Nerve Tumors
  • Peripheral Schwannoma
  • Periventricular Lesion
  • Periventricular Mass
  • Personal History of Malignant Neoplasm of Brain
  • Petrous Apex Tumor
  • Pilocytic Astrocytoma
  • Pineal Gland Parenchymal Tumor
  • Pineal Tumor
  • Pineoblastoma
  • Pituitary Adenoma
  • Pituitary Surgery
  • Pituitary Tumors
  • Posterior Cervical Laminectomy and Fusion
  • Posterior Lumbar Laminectomy
  • Post-Laminectomy Kyphosis
  • Post-Laminectomy Syndrome
  • Primary Brain Tumor
  • Prolactinoma
  • Radiculopathy
  • Rathke's Cleft Cysts
  • Repair of Brain
  • Resection of Cerebral Arteriovenous Malformation
  • Retinoblastoma
  • Revision of Spinal Surgery
  • Rhizotomy
  • Robotic Spine Surgery
  • Ruptured Brain Aneurysm
  • Ruptured Intervertebral Disc
  • Sacral Nerve Stimulation
  • Sacroiliac Joint Block
  • Sacroiliac Joint Fusion
  • Sacroiliac Joint Surgery
  • Scheuermann Disease
  • Scheuermann's Kyphosis
  • Schwannomatosis
  • Sciatica
  • Scoliosis Surgery
  • Selective Dorsal Rhizotomy
  • Sinonasal Undifferentiated Carcinoma
  • Skull Base Approach
  • Skull Base Tumors
  • Skull Fracture
  • Spina Bifida
  • Spinal Abscess
  • Spinal Abscess Surgery
  • Spinal Cord Cancer
  • Spinal Cord Compression
  • Spinal Cord Disorder
  • Spinal Cord Stimulator
  • Spinal Cord Surgery
  • Spinal Cord Tumors
  • Spinal Cyst Removal
  • Spinal Deformity
  • Spinal Dural Graft
  • Spinal Embolization
  • Spinal Fracture
  • Spinal Fusion
  • Spinal Mass
  • Spinal Meningioma
  • Spinal Microsurgery
  • Spinal Reconstruction
  • Spinal Schwannoma
  • Spinal Stenosis
  • Spinal Tethering for Scoliosis
  • Spinal Tumor
  • Spine Decompression
  • Spine Deformity
  • Spine Deformity Correction Surgery
  • Spine Injuries
  • Spine Stapling
  • Spondylectomy
  • Spondyloarthropathy
  • Spondylolisthesis
  • Spondylosis
  • Spondylosis Surgery
  • Spondylosis With Myelopathy
  • Spondylosyndesis
  • Spongioblastoma
  • Standard Transsphenoidal Approach
  • Stereotactic Brain Biopsy
  • Stereotactic EEG
  • Stereotactic Radiosurgery
  • Stereotactic Radiotherapy
  • Subarachnoid Hemorrhage
  • Subcaudate Tractotomy
  • Subdural Hematoma
  • Subdural Hemorrhage
  • Subependymal Giant Cell Astrocytoma
  • Subpial Transection
  • Superior Canal Dehiscence
  • Surgery for Sciatica
  • Surgery for Spasticity
  • Surgical Treatment of Myelopathy
  • Sympathectomy
  • Syringobulbia
  • Syringomyelia
  • Tarlov Cysts
  • Temporal Tumor
  • Tethered Spinal Cord
  • Thoracic Disc Herniation
  • Thoracic Laminectomy
  • Thoracic Spinal Fracture
  • Thoracic Spinal Fusion
  • Thoracic Spinal Injury
  • Thoracic Spinal Mass
  • Thoracic Spinal Stenosis
  • Thoracic Spinal Tumor
  • Topectomy
  • Transnasal Repair CSF Leak
  • Transpetrosal Approaches
  • Trigeminal Nerve Disorders
  • Ulnar Nerve Decompression
  • Ulnar Nerve Surgery
  • Vagal Nerve Stimulator
  • Vagal Stimulation
  • Vascular Brain Tumors
  • Vascular Malformations of the Brain
  • Vascular Malformations of the Spine
  • Vein of Galen Malformation
  • Venous Malformation Brain
  • Ventricular Shunt
  • Ventriculo Peritoneal Shunt
  • Ventriculocisternostomy
  • Ventriculostomy
  • Vertebrae Surgery
  • Vertebral Epiphysitis
  • Vertebral Fracture
  • Vertebral Stapling
  • Visualase MRI-Guided Laser Ablation
  • X-Stop Surgery
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Georgetown University School of Medicine
Residency: University of Virginia Health System

Memberships

American Academy of Neurological Surgery, National American Association for the Advancement of Science, National American Association of Neurological Surgeons, National American Board of Neurological Surgery, National American College of Surgeons, National Cervical Spine Research Society, National College of Physicians of Philadelphia, Local John Morgan Society, Local Joint Section, Neurotrauma & Critical Care (AANS/CNS), National Joint Section, Spine & Peripheral Nerves (AANS/CNS), National Neurosurgical Society of America, National Neurotrauma Society, National Pennsylvania Medical Society, Local Pennsylvania Neurosurgical Society, Local Philadelphia Neurological Society, Local Society of Neurological Surgeons, National Union League of Philadelphia, Local

Hospital Affiliation

Dr. Grady is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Dr. Grady's research interests include memory dysfunction resulting from traumatic brain injury and minimally invasive neurosurgery.

Selected Publications:

Lee JYK, Cho SS, Zeh R, Pierce JT, Martinez-Lage M, Adappa ND, Palmer JN, Newman JG, Learned KO, White C, Kharlip J, Snyder P, Low PS, Singhal S, Grady MS: Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging. J Neurosurg 129 (2): 390-403,2018.

Piazza M, Sharma N, Osiemo B, McClintock S, Missimer E, Gardiner D, Maloney E, Callahan D, Smith JL, Welch W, Schuster J, Grady MS, Malhotra NR: Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population. Neurosurgery : 2018.

Cho SS, Zeh R, Pierce JT, Jeon J, Nasrallah M, Adappa ND, Palmer JN, Newman JG, White C, Kharlip J, Snyder P, Low P, Singhal S, Grady MS, Lee JYK: Folate Receptor Near-Infrared Optical Imaging Provides Sensitive and Specific Intraoperative Visualization of Nonfunctional Pituitary Adenomas. Oper Neurosurg : 2018.

Swanson RL, Hampton S, Green-McKenzie J, Diaz-Arrastia R, Grady MS, Verma R, Biester R, Duda D, Wolf RL, Smith DH: Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba. JAMA 319 (11): 1125-1133,2018.

Ali ZS, Ma TS, Ozturk AK, Malhotra NR, Schuster JM, Marcotte PJ, Grady MS, Welch WC: Pre-optimization of spinal surgery patients: Development of a neurosurgical enhanced recovery after surgery (ERAS) protocol. Clin Neurol Neurosurg 164 : 142-153,2018.

Morris J, Na YJ, Zhu H, Lee JH, Giang H, Ulyanova AV, Baltuch GH, Brem S, Chen HI, Kung DK, Lucas TH, O'Rourke DM, Wolf JA, Grady MS, Sul JY, Kim J, Eberwine J: Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing. Cell Rep 21 (10): 2706-2713,2017.

Ma TS, Sharma N, Grady MS: A simplified pressure adjustment clinical pathway for programmable valves in NPH patients. Clin Neurol Neurosurg 159 : 83-86,2017.

Piazza M, Nayak N, Ali Z, Heuer G, Sanborn M, Stein S, Schuster J, Grady MS, Malhotra NR: Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms. World Neurosurg 103 : 194-200,2017.

Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK: Concussion Induces Hippocampal Circuitry Disruption in Swine. J Neurotrauma 34 (14): 2303-2314,2017.

Thawani JP, Ramayya AG, Pisapia JM, Abdullah KG, Lee JY, Grady MS: Operative Strategies to Minimize Complications Following Resection of Pituitary Macroadenomas. J Neurol Surg B Skull Base 78 (2): 184-190,2017.

Academic Contact Info

HUP - 3 Silverstein
3400 Spruce Street
clinical: 215.662.3483
administrative: 215.349.8325

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)

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