Penn Medicine Provider

About me

  • Professor of Orthopaedic Surgery

My Locations

Qualifications and experience

My research

Wang, H., He, X., Ma, M., Dou, T., Wei, Y., Rux, D., Qin, L., Yang, Y., Zhu, Y., and Yao, L. Integrating spatial and single-cell transcriptomics to characterize mouse long bone fracture healing process. , Commun. Biol. , 8: 2025,887


Zhang, J., Acosta, F.M., Wang, X., Zhao, D., Zhang, L., Hua, R., Guo, Q., Zhong, L., Qin, L., Riquelme, M.A., and Jiang, J.X. Osteocyte connexin hemichannels and prostaglandin E2 release dictate bone marrow mesenchymal stromal cell commitment. , Proc Natl Acad Sci USA , 122: 2025,e2412144122


Verginadisa, I.I.#, Velalopouloua, A.#, Kim, M.M., Kim, K., Paraskevaidis, I., Bell, B. Motlagha, S.A.O., Karaj, A., Banerjee, E. Finesso, G., Assenmacher, C., Radaelli, E., Lu, J., Lin, Y., Putt, M.E., Diffenderfer, E.S., Guha, C., Qin, L., Metza, J.M., Maity, A.*, Cengel, K.A*, Koumenis, C.*, and Busch, T.M.* FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone. , Radiother Oncol. , 205: 2025,110744


Lu, J., He, Q., Wang, H., Yao, L., Duffy, M., Guo, H., Braun, C., Zhou, Y., Liang, Q., Lin, Y., Bandyopadhyay, S., Tan, K., Choi, Y., Liu, S., and Qin, L. Bone marrow adipogenic lineage precursors are the major regulator of bone resorption in adult mice. , Bone Res. , 13: 2025,39


Wang, H.#, Yao, L.#, Zhong, L.#, Fang, J.#, He, Q., Busch, T., Cengel, K., and Qin, L. Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy. , Bone, 195: 2025,117446


He, Q.#, Lu, J.#, Liang, Q., Yao, L., Sun, T., Wang, H., Duffy, M., Jiang, X., Lin, Y., Lee, J., Ahn, J., Dyment, N., Mourkioti, F., Boerckel, J., and Qin, L. Prg4+ fibro-adipogenic progenitors in muscle are crucial for bone fracture repair. , Proc Natl Acad Sci USA, 122: 2025,e2417806122


Tang, S. #, Yao, L. #, Ruan, J., Kang, J., Cao, Y., Nie, X., Lan, W., Zhu, Z., Han, W., Liu, Y., Tian, J., Seale, P., Qin, L. *, Ding, C*. #: these authors contributed equally to this work. *: co-corresponding authors. Single-cell atlas of human infrapatellar fat pad and synovium unravels mechanisms of osteoarthritis-induced joint pathology. , Sci Transl Med. , 16: 2024,eadf4590


Collins, J.M., Lang, A., Parisi, C., Moharrer, Y., Nijsure, M.P., Kim, J.H., Szeto, G.L., Qin, L., Gottardi, R.L., Dyment, N.A., Nowlan, N.C., and Boerckel, J.D. YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development. , Dev. Cell. , 59: 2024,211-227


Li, J.#, Gui, T.#, Yao, L., Guo, H., Lin, Y., Lu, J., Fang, J., Duffy, M., Zgonis, M., Mauck, R., Dyment, N., Zhang, Y., Scanzello, C., Seale, P., and Qin, L. #: these authors contributed equally to this work. Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. , J Bone Miner Res. , 39: 2024,161-176


Tian, Z., Shofer F.S., Fan, M., Sandroni, A.Z., Yao, L., Han, L., Qin, L., Enomoto-Iwamoto, M., and Zhang, Y. ADAM8 inactivation retards intervertebral disc degeneration in mice. , Genes Dis. , 11: 2024,101059