Ling Qin, PhD
Penn Medicine Provider

About me

  • Professor of Orthopaedic Surgery

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My research

Wang, H.#, Yao, L.#, Zhong, L.#, Fang, J.#, He, Q., Busch, T., Cengel, K., and Qin, L. Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy. , Bone, 195: 2025,117446


He, Q.#, Lu, J.#, Liang, Q., Yao, L., Sun, T., Wang, H., Duffy, M., Jiang, X., Lin, Y., Lee, J., Ahn, J., Dyment, N., Mourkioti, F., Boerckel, J., and Qin, L. Prg4+ fibro-adipogenic progenitors in muscle are crucial for bone fracture repair. , Proc Natl Acad Sci USA, 122: 2025,e2417806122


Wang, H., He, X., Ma, M., Dou, T., Wei, Y., Rux, D., Qin, L., Yang, Y., Zhu, Y., and Yao, L. Integrating spatial and single-cell transcriptomics to characterize mouse long bone fracture healing process. , Commun. Biol. , 8: 2025,887


Zhang, J., Acosta, F.M., Wang, X., Zhao, D., Zhang, L., Hua, R., Guo, Q., Zhong, L., Qin, L., Riquelme, M.A., and Jiang, J.X. Osteocyte connexin hemichannels and prostaglandin E2 release dictate bone marrow mesenchymal stromal cell commitment. , Proc Natl Acad Sci USA , 122: 2025,e2412144122


Verginadisa, I.I.#, Velalopouloua, A.#, Kim, M.M., Kim, K., Paraskevaidis, I., Bell, B. Motlagha, S.A.O., Karaj, A., Banerjee, E. Finesso, G., Assenmacher, C., Radaelli, E., Lu, J., Lin, Y., Putt, M.E., Diffenderfer, E.S., Guha, C., Qin, L., Metza, J.M., Maity, A.*, Cengel, K.A*, Koumenis, C.*, and Busch, T.M.* FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone. , Radiother Oncol. , 205: 2025,110744


Lu, J., He, Q., Wang, H., Yao, L., Duffy, M., Guo, H., Braun, C., Zhou, Y., Liang, Q., Lin, Y., Bandyopadhyay, S., Tan, K., Choi, Y., Liu, S., and Qin, L. Bone marrow adipogenic lineage precursors are the major regulator of bone resorption in adult mice. , Bone Res. , 13: 2025,39


Chen, K., Tian, Z., Wang, H., Qin, L., Enomoto-Iwamoto, M., and Zhang, Y. Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. , Am. J. Phys. Med. , 104: 2024,45-50


Tang, S. #, Yao, L. #, Ruan, J., Kang, J., Cao, Y., Nie, X., Lan, W., Zhu, Z., Han, W., Liu, Y., Tian, J., Seale, P., Qin, L. *, Ding, C*. #: these authors contributed equally to this work. *: co-corresponding authors. Single-cell atlas of human infrapatellar fat pad and synovium unravels mechanisms of osteoarthritis-induced joint pathology. , Sci Transl Med. , 16: 2024,eadf4590


Chowdhury, P., Velalopoulou A., Verginadis, I., Morcos, G., Loo, P., Kim, M., Motlagh, S.Z.O., Shoniyozov, Kl, Diffenderfer, E., Ocampo, E., Putt, M., Assenmacher, C., Radaellli, E., Lu, J., Qin, L., Liu, H., Leli, N.M., Girdhani, S., Denef, N., Sappen, F., Cengel, K., Busch, T., Metz, J., Dong, L., Lin, A., and Koumenis, C. Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer. , Mol. Cancer Ther., 23: 2024,877-889


Bandyopadhyay, S., Duffy, M., Ahn, K.J., Pang, M., Smith, D., Duncan, G., Sussman, J., Zhang, I., Huang, J., Lin, Y., Xiong, B., Imtiaz, T., Chen, C., Thadi, A., Chen, C., Xu, J., Reichart, M., Pillai, V., Snaith, O., Oldridge, D., Bhattacharyya, S., Maillard, I., Carroll, M., Nelson, C., Qin, L.*, and Tan, K*. *: co-corresponding authors. Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic Imaging. , Cell, 187: 2024,3120-3140