Penn Medicine Provider
Ling Qin, PhD
About me
- Professor of Orthopaedic Surgery
My Locations
Qualifications and experience
- Abramson Cancer Center of the University of Pennsylvania, Local
- American Society for Bone and Mineral Research, National
- Association of Osteobiology, International
- Bone Marrow Adiposity Society, International
- Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Local
- Center for Advancement of Science in Space, National
- IACUC Committee, Local
- Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Local
- Institute for Regeneration Medicine, University of Pennsylvania, Local
- Institute on Aging, Local
- International Chinese Musculoskeletal Research Society, International
- International Society of Bone Morphometry, International
- National Society for Histotechnology, National
- NIAMS Arthritis and Musculoskeletal and Skin Diseases Study Section (AMS), National
- Orthopaedic Research Club, University of Pennsylvania, Philadelphia, PA, Local
- Orthopaedic Research Society, National
- Penn Center for Musculoskeletal Disorders, Local
- Penn Center for Musculoskeletal Disorders, University of Pennsylvania, Local
My research
Wang, H., He, X., Ma, M., Dou, T., Wei, Y., Rux, D., Qin, L., Yang, Y., Zhu, Y., and Yao, L. Integrating spatial and single-cell transcriptomics to characterize mouse long bone fracture healing process. , Commun. Biol. , 8: 2025,887
Zhang, J., Acosta, F.M., Wang, X., Zhao, D., Zhang, L., Hua, R., Guo, Q., Zhong, L., Qin, L., Riquelme, M.A., and Jiang, J.X. Osteocyte connexin hemichannels and prostaglandin E2 release dictate bone marrow mesenchymal stromal cell commitment. , Proc Natl Acad Sci USA , 122: 2025,e2412144122
Verginadisa, I.I.#, Velalopouloua, A.#, Kim, M.M., Kim, K., Paraskevaidis, I., Bell, B. Motlagha, S.A.O., Karaj, A., Banerjee, E. Finesso, G., Assenmacher, C., Radaelli, E., Lu, J., Lin, Y., Putt, M.E., Diffenderfer, E.S., Guha, C., Qin, L., Metza, J.M., Maity, A.*, Cengel, K.A*, Koumenis, C.*, and Busch, T.M.* FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone. , Radiother Oncol. , 205: 2025,110744
Lu, J., He, Q., Wang, H., Yao, L., Duffy, M., Guo, H., Braun, C., Zhou, Y., Liang, Q., Lin, Y., Bandyopadhyay, S., Tan, K., Choi, Y., Liu, S., and Qin, L. Bone marrow adipogenic lineage precursors are the major regulator of bone resorption in adult mice. , Bone Res. , 13: 2025,39
Wang, H.#, Yao, L.#, Zhong, L.#, Fang, J.#, He, Q., Busch, T., Cengel, K., and Qin, L. Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy. , Bone, 195: 2025,117446
He, Q.#, Lu, J.#, Liang, Q., Yao, L., Sun, T., Wang, H., Duffy, M., Jiang, X., Lin, Y., Lee, J., Ahn, J., Dyment, N., Mourkioti, F., Boerckel, J., and Qin, L. Prg4+ fibro-adipogenic progenitors in muscle are crucial for bone fracture repair. , Proc Natl Acad Sci USA, 122: 2025,e2417806122
Tang, S. #, Yao, L. #, Ruan, J., Kang, J., Cao, Y., Nie, X., Lan, W., Zhu, Z., Han, W., Liu, Y., Tian, J., Seale, P., Qin, L. *, Ding, C*. #: these authors contributed equally to this work. *: co-corresponding authors. Single-cell atlas of human infrapatellar fat pad and synovium unravels mechanisms of osteoarthritis-induced joint pathology. , Sci Transl Med. , 16: 2024,eadf4590
Collins, J.M., Lang, A., Parisi, C., Moharrer, Y., Nijsure, M.P., Kim, J.H., Szeto, G.L., Qin, L., Gottardi, R.L., Dyment, N.A., Nowlan, N.C., and Boerckel, J.D. YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development. , Dev. Cell. , 59: 2024,211-227
Li, J.#, Gui, T.#, Yao, L., Guo, H., Lin, Y., Lu, J., Fang, J., Duffy, M., Zgonis, M., Mauck, R., Dyment, N., Zhang, Y., Scanzello, C., Seale, P., and Qin, L. #: these authors contributed equally to this work. Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. , J Bone Miner Res. , 39: 2024,161-176
Tian, Z., Shofer F.S., Fan, M., Sandroni, A.Z., Yao, L., Han, L., Qin, L., Enomoto-Iwamoto, M., and Zhang, Y. ADAM8 inactivation retards intervertebral disc degeneration in mice. , Genes Dis. , 11: 2024,101059