Dr. Jacobs is the founding Director of the Cancer Survivorship Center of Excellence at Penn, founded in 2001. The Survivorship Program at the Abramson Cancer Center is a multidisciplinary initiative incorporating clinical, research, and education areas. She develops and oversees all of the survivorship clinical programs. As a researcher, she examines the co-morbidities experienced by survivors as a result of a cancer diagnosis and treatment. Dr. Jacobs' research interests focus on cardiovascular, reproductive, endocrine, quality of life, and other long-term and late effects of cancer treatment, clinical and genetic risk assessment, treatment summaries and survivorship care plans, and health behavior modification.