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Leslie A. Litzky, MD

Leslie A. Litzky, MD Physician

Director, Section of Medical Pathology Interim Director of Surgical Pathology Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania

Dr. Litzky is employed by Penn Medicine.

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About Dr. Leslie A. Litzky

Recognized by Best Doctors in America 2017 - 2018

Clinical Specialties


  • Pathology and Laboratory Medicine

Programs & Centers:

Board Certification:

  • Pathology - Anatomic and Clinical Pathology, 1992

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: George Washington University
Residency: Hospital of the University of Pennsylvania
Fellowship: George Washington University Medical Center


American Society of Clinical Pathologists, National American Thoracic Society, National International Association for the Study of Lung Cancer, International Pathology Society of Philadelphia, Local Pennsylvania Thoracic Society, Local Pulmonary Pathology Society, National United States/Canadian Academy of Pathology (USCAP), National

Hospital Affiliation

Dr. Litzky is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Sterman DH, Alley E, Stevenson JP, Friedberg J, Metzger S, Recio A, Moon EK, Haas AR, Vachani A, Katz SI, Sun J, Heitjan D, Hwang WT, Litzky L, Yearley JH, Tan KS, Papasavvas E, Kennedy P, Montaner L, Cengel KA, Simone CB, Culligan M, Langer C, Albelda SM: Pilot and feasibility trial of immuno-gene therapy of malignant mesothelioma using intrapleural delivery of adenovirus-interferon-alpha combined with chemotherapy Clin Cancer Res 22 (15): 3791-800,2016.

Kennedy GT, Okusanya OT, Keating JJ, Heitjan DD, Deshpande C, Litzky LA, Albelda SM, Drebin JA, Nie S, Low PS, Singhal S: The optical biopsy: a novel technique for rapid intraoperative diagnosis of primary pulmonary adenocarcinomas Ann Surg : 602-9,2015.

Husain AN, Colby T, Ordonez N, Krausz T, Attanoos R, Beasley MB, Borczuk AC, Butnor K, Cagle PT, Chirieac LR, Churg A, Dacic S, Fraire A, Galateau-Salle F, Gibbs A, Gown A, Hammar S, Litzky L, Marchevsky AM, Nicholson A, Roggli V, Travis WD, Wick M: Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group Arch Pathol Lab Med 137 (5): 647-667,2013.

Zamani P, Kirkpatrick JN, Litzky LA, Verdino RJ: Longevity of implantable devices explanted from patients having autopsy in hospitals Am J Cardiol 110 (11): 1643-1645,2012.

McDonough JE, Yuan R, Suzuki M, Seyednejad N, Elliott WM, Sanchez PG, Wright AC, Gefter WB, Litzky L, Coxson HO, Pare PD, Sin DD, Pierce RA, Woods JC, McWilliams AM, Mayo JR, Lam SC, Cooper JD, Hogg JC: Small-airway obstruction and emphysema in chronic obstructive pulmonary disease N Engl J Med 365 (17): 1567-75,2011.

Litzky, LA: Pulmonary neuroendocrine tumors Surgical Pathology Clinics : 2010.

Litzky LA: Pulmonary sarcomatous tumors. Arch Pathol Lab Med 132 : 1104-1117 ,2008.

Chu AY, Litzky LA, Pasha TL, Acs G, Zhang PJ: Utility of D2-40, a novel mesothelial marker, in the diagnosis of malignant mesothelioma. Mod Pathol 18 : 105-110,2005.

Katzenstein A-LA, Zisman DA, Litzky LA, Nguyen BT, Kotloff RM.: Usual and non-specific interstitial pneumonia. Pathologic appraisal using biopsy and explant specimens. Am J Surg Pathol 12 : 1567-1577,2002.

Amin KM, Litzky LA, Smythe WR, Mooney AM, Morris JM, Mews DJY, Pass HI, Kari C, Rodeck U, Rauscher FJ, Kaiser LR, Albelda SM: The Wilms' Tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma Am J Pathol 146 : 344-356,1995.

Academic Contact Info

Department of Pathology & Laboratory Medicine
6 Founders Building
Hospital of the University of Pennsylvania
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-3215

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