Penn Medicine Provider
Renal Electrolyte and Hypertension
Lawrence B. Holzman, MD
5.0
(108)
Accepting new patients
Sees patients age 18 and up
Penn Renal Electrolyte and Hypertension Perelman

About me

  • Chief, Renal-Electrolyte and Hypertension
  • C. Mahlon Kline Professor of Medicine
  • Professor of Medicine in Pediatrics

Education and training

  • Medical School: University of Medicine and Dentistry of New Jersey
  • Residency: Medical College of Pennsylvania
  • Fellowship: University of Michigan Medical Center

What my patients think about me

Average Rating
5.0

108 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

April 2025
5.0
5.0
dr holzman is very knowledgeable.
April 2025
5.0
5.0
dr. h is a great doctor!
April 2025
5.0
5.0
dr. holzman is an excellent, knowledgeable and caring doctor
April 2025
5.0
5.0
very knowledgeable about my ckd

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Dr. Holzman is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Spinale Joann M, Mariani Laura H, Kapoor Shiv, Zhang Jidong, Weyant Robert, Song Peter X, Wong Hetty N, Troost Jonathan P, Gadegbeku Crystal A, Gipson Debbie S, Kretzler Matthias, Nihalani Deepak, Holzman Lawrence B A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease. , Kidney international, 87(3): 2015,564-74


Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PXK, Barisoni L, Sampson MG, Kopp JB, Lemley KV, Nelson PJ, Lienczewski CC, Adler SG, Appel GB, Cattran DC, Choi MJ, Contreras G, Dell KM, Fervenza FC, Gibson KL, Greenbaum LA, Hernandez JD, Hewitt SM, Hingorani SR, Hladunewich M, Hogan MC, Hogan SL, Kaskel FJ, Lieske JC, Meyers KEC, Nachman PH, Nast CC, Neu AM, Reich HN, Sedor JR, Sethna CB, Trachtman H, Tuttle KR, Zhdanova O, Zilleruelo GE, Kretzler M Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. , Kidney Int, 83(4): 2013,749-56


George B, Verma R, Soofi AA, Garg P, Zhang J, Park T, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Curran T, Rastaldi MP, and Holzman LB Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mice , J Clin Invest, 122(2): 2012,674-92


Deepak N, Wong H, Verma R, Holzman LB Src Family Kinases Directly Regulate JIP1 Module Dynamics and Activation , Mol Cell Biol, 27(7): 2007,2431-2441


Verma R, Kovari I, Abdul S, Nihalani D, Patrie K, Holzman LB Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization , J Clin Invest, 116(5): 2006,1346-1359


Moeller MJ, Soofi A, Sanden S, Floege J, Kriz W, Holzman LB An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo , Am J Physiol Renal Physiol, 289(2): 2005,F481-F488


Moeller MJ, Soofi A, Watzel C, Kriz W, Holzman LB Protocadherin FAT1 binds Ena/VASP and is necessary for lamellipodial dynamics, cell polarization, and cell migration , EMBO J, 23(19): 2004,3769-3779


Holzman LB, St. John P, Kovari I, Verma R, Holthofer H, Abrahamson D Nephrin is localized to the slit pore of the glomerular epithelial cell , Kidney Intl, 56(4): 1999,1481-1491


Nihalani D, Meyer D, Pajni S, Holzman LB Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components , EMBO J, 20(13): 2001,3447-3458


Holzman LB, Merritt S, Fan G Identification, molecular cloning, and characterization of Dual Leucine Zipper Kinase: a novel serine/threonine kinase that defines a second subfamily of MLK kinases , J Biol Chem, 269(49): 1994,30808-30817