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Laura M. Dember, MD

Laura M. Dember, MD Physician

Professor of Medicine at the Hospital of the University of Pennsylvania
Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Dember is a Penn Medicine employed physician.

About Dr. Laura M. Dember

Recognized by America's Top Doctors, 2012-14

Clinical Specialties


  • Medicine
    • Renal Electrolyte and Hypertension

Programs & Centers:

Board Certification:

  • Nephrology, 1994

Description of Clinical Expertise

Dr. Dember has more than 20 years of experience as a general nephrologist and has internationally-recognized expertise in the systemic amyloidoses, a group of rare disorders that often affect the kidneys. She is a member of the University of Pennsylvania multidisciplinary amyloidosis program that evaluates and treats patients with all types of amyloidosis.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Yale University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania
Fellowship: Brigham and Women's Hospital


American College of Physicians, National College of Physicians of Philadelphia, Local International Society of Nephrology, International Massachusetts Medical Society, Local National Kidney Foundation, National

Hospital Affiliation

Dr. Dember is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Dember conducts patient-oriented research including mechanistic studies and clinical trials in chronic kidney disease and end-stage renal disease (ESRD). She has particular interests in hemodialysis vascular access and interventions to improve clinical outcomes in end-stage renal disease. Her research is funded by the National Institutes of Health. Dr. Dember is Principal Investigator for the Data Coordinating Center of the NIDDK Hemodialysis Novel Therapies Consortium which is conducting early phase clinical trials targeting ESRD-associated inflammation, and she is the Principal Investigator for the "TiME Trial", a large, pragmatic cluster-randomized clinical trial being conducted through the NIH Health Care Systems Research Collaboratory, The TiME Trial will enroll 6400 participants at 400 dialysis units throughout the United States using a highly centralized and efficient implementation approach leveraging the infrastructure of dialysis provider organizations. Dr. Dember is also a principal investigator for the NIDDK Hemodialysis Fistula Maturation Study -- an observational cohort study designed to elucidate predictors and mechanisms of arteriovenous fistula maturation.

Selected Publications:

Tachibana C, Johnson KE, Coronado GD, Dember LM, Glasgow RE, Huang SS, Martin PJ, Richards J, Rosenthal G, Septimus E, Simon GE, Solberg L, Suls J, Thompson E, Larson EB: A guide to research partnerships for pragmatic clinical trials. BMJ 349 : g6826,2014.

Terry CM, Dember LM: Novel Therapies for Hemodialysis Vascular Access Dysfunction Clin J Am Soc Nephrol 8 : 2202-12,2013.

Peden EK, Leeser DB, Dixon BS, El-Khatib MT, Roy-Chaudhury P, Lawson JH, Menard MT, Dember LM, Glickman MH, Gustafson PN, Blair AT, Magill M, Franano FN, Burke SK.: A multi-center, dose-escalation study of human type 1 pancreatic elastase (PRT-201) administered after arterovenous fistula creation. J Vasc Access 14 (2): 143-51,2013.

Dember LM: Fistulas first - But can they last? Clin J Am Soc Nephrol 6 (13): 463-4,2011.

Cibeira MT, Sanchorawala V, Seldin DC, Quillen K, Berk JL, Dember LM, Segal A, Ruberg F, Meier-Ewert H, Andrea NT, Sloan JM, Finn KT, Doros G, Blade J, Skinner M: Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients Blood : {Epub ahead of print],2011.

Dixon BS, Beck GJ, Vazquez MA, Greenberg A, Delmez JA, Allon M, Dember LM, Himmelfarb J, Gassman JJ, Greene T, Radeva MK, Davidson IJ, Ikizler TA, Braden GL, Fenves AZ, Kaufman JS, Cotton JR, Martin KJ, McNei JW, Rahman A, Lawson JH, Whiting JF, Hu B, Meyers CM, Kusek JW, Feldman HI, Dialysis Access Consortium (DAC) Study Group: Effect of dipyridamole plus aspirin on hemodialysis graft patency N Engl J Med 360 : 2191-2201,2009.

Dember LM, Beck GJ, Allon M, Delmez J, Dixon BS, Greenberg A, Himmelfarb J, Vazquez VA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI. Dialysis Access Consortium (DAC) Study Group: Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized, controlled trial JAMA 299 : 2164-71,2008.

Dember LM, Hawkins PN, Hazenberg BPC, Gorevic PD, Merlini G, Butriemene I, Livneh A, Lesnyak O, puechal X, Lachmann H, Obici L, Balshaw R, Garceau D, Hauck W. Skinner M: Eprodisate for the treatment of renal disease in AA amyloidosis N Engl J Med 356 : 2349-60,2007.

Academic Contact Info

Renal-Electrolyte and Hypertension Division
Perelman School of Medicine, University of Pennsylvania
Blockley Hall, Office 920
423 Guardian Drive

Philadelphia, PA 19104
Phone: (215) 573-5264
Fax: (215) 615-0349
Patient appointments: 800-789-PENN (7366)