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Laura M. Dember, MD

Laura M. Dember, MD Physician

Professor of Medicine at the Hospital of the University of Pennsylvania
Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Dember is a Penn Medicine employed physician.

About Dr. Laura M. Dember

Recognized by America's Top Doctors, 2012-14

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties

Specialty:

  • Renal Electrolyte and Hypertension

Programs & Centers:

Board Certification:

  • Nephrology, 1994

Description of Clinical Expertise

Dr. Dember has more than 20 years of experience as a general nephrologist and has internationally-recognized expertise in the systemic amyloidoses, a group of rare disorders that often affect the kidneys. She is a member of the University of Pennsylvania multidisciplinary amyloidosis program that evaluates and treats patients with all types of amyloidosis.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Yale University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania
Fellowship: Brigham and Women's Hospital

Memberships

American College of Physicians, National American Society of Nephrology, National College of Physicians of Philadelphia, Local Duke NIDDK O'Brien Kidney Center, Member, External Advisory Committee, National FDA-ASN Kidney Health Initiative, Core Committee Member, Clinical Trial Endpoints in Dialysis Vascular Access, National FDA-ASN Kidney Health Initiative, Workgroup Chair, Pragmatic Trials in Nephrology: Challenges and Opportunities, National International Society of Nephrology, International Kidney Disease: Improving Global Outcomes, Invited Member, Controversies Conference: "Challenges in the Conduct of Clinical Trials in Nephrology Controversies"; Paris, France, International Massachusetts Medical Society, Local National Institutes of Diabetes and Digestive and Kidney Diseases, Chair, Forms Committee, Hemodialysis Novel Therapies Consortium, National National Institutes of Diabetes and Digestive and Kidney Diseases, Chair, Steering Committee, Time to Reduce Mortality in End-Stage Renal Disease Trial, National National Institutes of Diabetes and Digestive and Kidney Diseases, Member, Executive Committee, Hemodialysis Novel Therapies Consortium, National National Institutes of Diabetes and Digestive and Kidney Diseases, Member, Publications and Ancillary Studies Committee, Hemodialysis Fistula Maturation Consortium, National National Institutes of Diabetes and Digestive and Kidney Diseases, Member, Safety Committee, Hemodialysis Novel Therapies Consortium, National National Institutes of Diabetes and Digestive and Kidney Diseases, Member, Steering Committee, Hemodialysis Fistula Maturation Consortium, National National Kidney Foundation, National NIH Health Care Systems Research Collaboratory, Member, Health Care Systems Interactions Working Group, National

Hospital Affiliation

Dr. Dember is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Dr. Dember conducts patient-oriented research including mechanistic studies and clinical trials in chronic kidney disease and end-stage renal disease (ESRD). She has particular interests in hemodialysis vascular access and interventions to improve clinical outcomes in end-stage renal disease. Her research is funded by the National Institutes of Health. Dr. Dember is Principal Investigator for the Data Coordinating Center of the NIDDK Hemodialysis Novel Therapies Consortium which is conducting early phase clinical trials targeting ESRD-associated inflammation and cardiovascular disease, and she is the Principal Investigator for the "TiME Trial", a large, pragmatic cluster-randomized clinical trial being conducted through the NIH Health Care Systems Research Collaboratory. The TiME Trial has enrolled 6800 participants at more than 250 dialysis units throughout the United States and uses highly centralized implementation and data collection approaches that leverage the infrastructure and clinical care delivery systems of dialysis provider organizations. Dr. Dember is also a principal investigator for the NIDDK Hemodialysis Fistula Maturation Study -- an observational cohort study designed to elucidate predictors and mechanisms of arteriovenous fistula maturation, and she is a member of the Scientific and Data Coordinating Center for the NIDDK Chronic Renal Insufficiency Cohort Study.

Selected Publications:

Dember LM, Archdeacon P, Krishnan M, Lacson E, Ling SM, Roy-Chaudhury P, Smith KA, Flessner MF: Pragmatic Trials in Maintenance Dialysis: Perspectives from the Kidney Health Initiative. J Am Soc Nephrol : 2016.

Allon M, Greene T, Dember LM, Vita JA, Cheung AK, Hamburg NM, Imrey PB, Kaufman JS, Robbin ML, Shiu Y-T, Terry CM, Umphrey HR, Feldman HI: Association between Preoperative Vascular Function and Postoperative Arteriovenous Fistula Development. J Amer Soc Nephrol : 2016.

Tachibana C, Johnson KE, Coronado GD, Dember LM, Glasgow RE, Huang SS, Martin PJ, Richards J, Rosenthal G, Septimus E, Simon GE, Solberg L, Suls J, Thompson E, Larson EB: A guide to research partnerships for pragmatic clinical trials. BMJ 349 : g6826,2014.

Terry CM, Dember LM: Novel Therapies for Hemodialysis Vascular Access Dysfunction Clin J Am Soc Nephrol 8 : 2202-12,2013.

Peden EK, Leeser DB, Dixon BS, El-Khatib MT, Roy-Chaudhury P, Lawson JH, Menard MT, Dember LM, Glickman MH, Gustafson PN, Blair AT, Magill M, Franano FN, Burke SK.: A multi-center, dose-escalation study of human type 1 pancreatic elastase (PRT-201) administered after arterovenous fistula creation. J Vasc Access 14 (2): 143-51,2013.

Dember LM: Fistulas first - But can they last? Clin J Am Soc Nephrol 6 (13): 463-4,2011.

Cibeira MT, Sanchorawala V, Seldin DC, Quillen K, Berk JL, Dember LM, Segal A, Ruberg F, Meier-Ewert H, Andrea NT, Sloan JM, Finn KT, Doros G, Blade J, Skinner M: Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients Blood : {Epub ahead of print],2011.

Dixon BS, Beck GJ, Vazquez MA, Greenberg A, Delmez JA, Allon M, Dember LM, Himmelfarb J, Gassman JJ, Greene T, Radeva MK, Davidson IJ, Ikizler TA, Braden GL, Fenves AZ, Kaufman JS, Cotton JR, Martin KJ, McNei JW, Rahman A, Lawson JH, Whiting JF, Hu B, Meyers CM, Kusek JW, Feldman HI, Dialysis Access Consortium (DAC) Study Group: Effect of dipyridamole plus aspirin on hemodialysis graft patency N Engl J Med 360 : 2191-2201,2009.

Dember LM, Beck GJ, Allon M, Delmez J, Dixon BS, Greenberg A, Himmelfarb J, Vazquez VA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI. Dialysis Access Consortium (DAC) Study Group: Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized, controlled trial JAMA 299 : 2164-71,2008.

Dember LM, Hawkins PN, Hazenberg BPC, Gorevic PD, Merlini G, Butriemene I, Livneh A, Lesnyak O, puechal X, Lachmann H, Obici L, Balshaw R, Garceau D, Hauck W. Skinner M: Eprodisate for the treatment of renal disease in AA amyloidosis N Engl J Med 356 : 2349-60,2007.

Academic Contact Info

Renal-Electrolyte and Hypertension Division
University of Pennsylvania Perelman School of Medicine
Center for Clinical Epidemiology and Biostatistics
Blockley Hall, Office 920
423 Guardian Drive

Philadelphia, PA 19104
Phone: (215) 573-5264
Fax: (215) 615-0349
Patient appointments: 800-789-PENN (7366)