Penn Medicine Provider
Neurology
Kyra O'Brien, MD, MSHP
4.9
(212)
Accepting new patients
Sees patients age 18 and up
Penn Neuroscience Center - Neurology

About me

  • Assistant Professor of Neurology at the Hospital of the University of Pennsylvania

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Hospital of the University of Pennsylvania
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
4.9

212 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

May 2025
5.0
5.0
excellent doctor
May 2025
5.0
5.0
we trust you.
May 2025
4.0
4.0
was pleased with the visit
April 2025
5.0
5.0
the provider was great, i just didn't like the questions she was asking me.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. O'Brien is a Penn Medicine physician.

Qualifications and experience

My research

O'Brien K, Harkins K, Peifer M, Kleid M, Coykendall C, Shea J, Karlawish J, Burke R Designing an Intervention to Improve Cognitive Evaluations in Primary Care , Implementation Science Communications, 6(9): 2025


Erickson C, Largent EA, O'Brien K Paving the way for Alzheimer’s blood-based biomarkers in primary care , Alzheimer's & Dementia: 2024


O'Brien K, Largent E A., Karlawish J Applying recommendations for diagnostic disclosure of mild cognitive impairment and dementia: Practical guidance for clinicians , Alzheimer's & Dementia: 2024


O’Brien, K.S., Mechanic-Hamilton, D.J., Rascovsky, K., Hamilton, R.H Degenerative Disorders of Cognition , Achieving Equity in Neurological Practice: Principles and Pathways: 2024,71-89


Cousins KAQ, Phillips JS, Das SR, O'Brien K, Tropea TF, Chen-Plotkin A, Shaw LM, Nasrallah IM, Mechanic-Hamilton D, McMillan CT, Irwin DJ, Lee EB, Wolk DA Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease , Alzheimer's & Dementia, 20(6): 2024,3889-3905


Kyra O’Brien MD, Kristin Harkins MPH, MaryAnne Peifer MD MSIS, Melanie Kleid, Cameron Coykendall, Robert Burke MD MS, Judy Shea PhD, Jason Karlawish MD Clinician-reported factors influencing performance of cognitive evaluations in primary care , Poster session presented at the 2024 American Academy of Neurology Annual Meeting, Denver, CO: 2024


O'Brien K, Coykendall C, Kleid M, Harkins K, Chin N, Clapp JT, Karlawish J Determinants of Plasma Alzheimer’s Disease Biomarker Use by Primary Care Providers and Dementia Specialists , Journal of General Internal Medicine, 39(9): 2024,1713-1720


Bennett AV, O'Brien K, Moreno M, Lanigan K, Maslow K, Malone CA, Hanson LC, Zimmerman S, Karlawish J, Largent EA, Aranda MP, Hinton L, Nicholson BP, Phillips L, Fazio S, Epstein-Lubow G. Development of a Lived Experience Panel to inform the design of embedded pragmatic trials of dementia care interventions , Journal of the American Geriatrics Society, 72(1): 2023,139-148


O'Brien K, Feng R, Sieber F, Marcantonio ER, Tierney A, Magaziner J, Carson JL, Dillane D, Sessler DI, Menio D, Ayad S, Stone T, Papp S, Schwenk ES, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Karlawish J, Mehta S, Donegan DJ, Horan A, Ellenberg SS, Neuman MD Outcomes with spinal versus general anesthesia for patients with and without preoperative cognitive impairment: Secondary analysis of a randomized clinical trial , Alzheimer's & Dementia, 19(9): 2023,4008-4019


Kyra O’Brien MD, Justin Clapp PhD MPH, Shana D. Stites PsyD MS MA, Kristin Harkins MPH, Cameron Coykendall, Melanie Kleid, Jason Karlawish MD, Emily Largent JD PhD RN Improving hospitalizations and care transitions for people living with dementia: Lessons from the COVID-19 pandemic , Poster session presented at the 2023 Annual Scientific Meeting of the American Geriatrics Society: 2023