Kenneth S. Shindler, MD, PhD
Ophthalmology
Accepting new patients
Sees patients age 18 and up
Scheie Eye Institute Penn Presbyterian
Make an appointmentCall 215-662-8100
Penn Medicine Provider

About me

  • F.M. Kirby Professor of Ophthalmology

Education and training

  • Medical School: Washington University School of Medicine
  • Residency: Penn Presbyterian Medical Center
  • Residency: Scheie Eye Institute
  • Fellowship: Scheie Eye Institute

What my patients think about me

Average Rating

126 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

October 2025
the provider dismissed symptoms, was reductive.
October 2025
very professional
September 2025
doctor's expertise and providing the right diagnosis
September 2025
highly recommended, exceeded expectations

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Shindler is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

McDougald DS, Dine KE, Zezulin AU, Bennett J, Shindler KS SIRT1 and NRF2 Gene Transfer Mediate Distinct Neuroprotective Effects Upon Retinal Ganglion Cell Survival and Function in Experimental Optic Neuritis , Invest. Ophthalmol. Vis. Sci., 59: 2018,1212-1220

Grinblat GA, Khan RS, Dine K, Wessel H, Brown L, Shindler KS RGC Neuroprotection Following Optic Nerve Trauma Mediated By Intranasal Delivery of Amnion Cell Secretome , Invest. Ophthalmol. Vis. Sci. , 59: 2018,2470-2477

Khan RS, Dine K, Bauman B, Lorentsen M, Lin L, Brown H, Hanson LR, Svitak AL, Wessel H, Brown L, Shindler KS Intranasal Delivery of A Novel Amnion Cell Secretome Prevents Neuronal Damage and Preserves Function In A Mouse Multiple Sclerosis Model , Sci. Rep., 7: 2017,41768

Khan RS, Dine K, Das Sarma J, Shindler KS SIRT1 activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease , Acta Neuropathol. Commun., 2(1): 2014,3

Zuo L, Khan RS, Lee V, Dine K, Wu W, Shindler KS SIRT1 promotes RGC survival and delays loss of function following optic nerve crush , Invest. Ophthalmol. Vis. Sci., 54(7): 2013,5097-102

Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity , J. Neurosci., 33(8): 2013,3582-7

Fonseca-Kelly Z, Nassrallah M, Uribe J, Khan RS, Dine K, Dutt M, Shindler KS Resveratrol neuroprotection in a chronic mouse model of multiple sclerosis , Front. Neurol., 3: 2012,84

Shindler KS, Chatterjee D, Biswas K, Goyal A, Dutt M, Nassrallah M, Khan RS, Das Sarma J Macrophage-mediated optic neuritis induced by retrograde axonal transport of spike gene recombinant mouse hepatitis virus , J. Neuropathol. Exp. Neurol., 70(6): 2011,470-80

Shindler KS, Ventura E, Dutt M, Elliott P, Fitzgerald DC, Rostami A Oral resveratrol reduces neuronal damage in a model of multiple sclerosis , J. of Neuro-Ophthalmol., 30(4): 2010,328-39

Das Sarma J, Kenyon LC, Hingley ST, Shindler KS Mechanisms of primary axonal damage in a viral model of multiple sclerosis , J. Neurosci., 29(33): 2009,10272-10280

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