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Kenneth D. Rothstein, MD

Kenneth D. Rothstein, MD Physician

Director of Regional Outreach and Regional Hepatology Professor of Clinical Medicine

Dr. Rothstein is employed by Penn Medicine.

In New Jersey, providers are affiliated with Penn Medicine through Clinical Health Care Associates of New Jersey.

About Dr. Kenneth D. Rothstein

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Gastroenterology

Programs & Centers:

Board Certification:

  • Gastroenterology, 1991
  • Internal Medicine, 1989
  • Transplant Hepatology, 2006

Clinical Expertise:

  • Abnormal Liver Function
  • Acholic Stools
  • Alcoholic Cirrhosis
  • Alcoholic Hepatitis
  • Alcoholic Liver Disease
  • Ascites
  • Autoimmune Hepatitis
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Diseases
  • Bile Duct Tumor
  • Biliary Cirrhosis
  • Biliary Tract Disorders
  • Cholangitis
  • Cholestasis
  • Chronic Liver Disease
  • Chronic Liver Inflammation
  • Drug-Induced Liver Injury
  • Esophageal Varices
  • Fatty Liver Diseases
  • Fibrocystic Liver
  • Focal Nodular Hyperplasia
  • Gallbladder Cancer
  • Gallbladder Disorders
  • Hemochromatosis
  • Hepatic Cyst
  • Hepatic Encephalopathy
  • Hepatitis
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis D
  • Hepatitis E
  • Hepatoblastoma
  • Hepatomegaly
  • Hepatorenal Syndrome
  • Hepatosplenomegaly
  • Hyperbilirubinemia
  • Hypoalbuminemia
  • Jaundice
  • Liver Cancer
  • Liver Cirrhosis
  • Liver Diseases
  • Liver Failure
  • Liver Hemangioma
  • Liver Mass
  • Liver Metastases
  • Metabolic Liver Disease
  • Necrosis of Liver
  • Non-Alcoholic Cirrhosis
  • Non-Alcoholic Fatty Liver Disease
  • Obstructive Jaundice
  • Pancreaticobiliary Disease
  • Portal Hypertension
  • Portal Hypertensive Gastropathy
  • Portal Vein Thrombosis
  • Primary Biliary Cholangitis
  • Primary Biliary Cirrhosis
  • Sclerosing Cholangitis
  • Secondary Biliary Cirrhosis
  • Toxic Liver Injury
  • Transaminitis
  • Wilson's Disease
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • DE Medicare
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Emory University
Residency: Emory University
Fellowship: Temple University Hospital


American Association for the Study of Liver Disease, National American College of Physicians, National Hepatitis B Foundation Medical Committee, National

Hospital Affiliation

Dr. Rothstein is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Manickavasagan H, Bianco B, Trebelev A, Rothstein K, and Munoz S.: Correction of coagulopathy prior to paracentesis is associated with excessive albumin administration and no apparent clinical benefit. Digest Diseases Week : 2016.

Amin A, Modi R, Riera A, Patel V, Munoz S, and Rothstein K.: Post-operative mortality in cirrhotics has decreased over the past decade: MELD score as currently used overestimates post operative mortality. Digestive Disease Week : 2016.

Munoz S, Rothstein K, and Gibas A: Hepatitis C Virus Infection: A New Era Contemporary Liver Transplantation : 1-8,2016.

Oustecky D, Riera A, and Rothstein K.: Long-Term Management of the Liver Transplant Recipient: Pearls for the Practicing Gastroenterologist Gastroenterol Clin North America 40(3) : 659-81,2011.

Mehta G, Rothstein K: Health Maintenance Issues in Cirrhosis Care of the Cirrhotic Patient 93 : 901-915,2009.

Bacon BA, Shiffman M, Mendes F, Ghalib R, Hassanein T, Morelli G, Joshi S, Rothstein K.: Retreating Chronic Hepatitis C with daily interferon Alfacon-1/Ribavirin after nonresponse to Pegylated Interferon/Ribavirin: DIRECT results. Hepatology 49 (6): 1838-1846,2009.

Ortiz JA, Manzarbeitia C, Noto KA, Reich D, Rothstein K: Extended survival after urgent liver transplantation from a liver procured from a donor harboring aortic arch sarcoma with metastasis to the liver and spleen, and bilateral renal cell carcinomas . Amer J Transplant 5 : 1559-1569,2005.

Briceno PJ1, Ortiz JA, Manzarbeitia C, Jeon H, Munoz SJ, Rothstein KD, Araya V, Gala I, Reich DJ.: Liver Transplantation using organ donor with HELLP syndrome Transplantation 78 (2): 137-139,2004.

Perrillo R1, Rothstein KD, Rubin R, Alam I, Imperial J, Harb G, Hu S, Klaskala W.: Comparison of quality of life, work productivity, and medical resource utilization of PEG-Interferon alfa 2a versus the combination of interferon alfa b plus ribavirin as initial treatment in patients with Chronic Hepatitis C. J Viral Hepat 11 (8): 157-165,2004.

Maraj S1, Jacobs LE, Maraj R, Contreras R, Rerkpattanapipat P, Malik TA, Manzarbeitia C, Munoz S, Rothstein K, Kotler MN.: Inducible left ventricular outflow tract gradient during dobutamine stress echocardiography: an association with intraoperative hypotension but not a contradiction to liver transplantation. Echocardiography 21 (8): 681-685,2004.

Academic Contact Info

3400 Civic Center Boulevard
7 South Pavilion

Philadelphia, PA 19104
Phone: (215) 349-8222
Patient appointments: 800-789-7366 (PENN)